Vrieler, Nora Loyola, Sebastian Yarden-Rabinowitz, Yasmin Hoogendorp, Jesse Medvedev, Nikolay Hoogland, Tycho M. De Zeeuw, Chris I. De Schutter, Erik Yarom, Yosef Negrello, Mario
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Published in
Brain Structure and Function
The inferior olive (IO) is an evolutionarily conserved brain stem structure and its output activity plays a major role in the cerebellar computation necessary for controlling the temporal accuracy of motor behavior. The precise timing and synchronization of IO network activity has been attributed to the dendro-dendritic gap junctions mediating elec...
Klein, Marie Muguet Cholvin, Thibault Cosquer, Brigitte Salvadori, Aurélie Le Mero, Julia Kourouma, Lola Boutillier, Anne-Laurence Pereira De Vasconcelos, Anne Cassel, Jean-Christophe
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Martínez-Rodríguez, Elena Martín-Sánchez, Ana Coviello, Simona Foiani, Cristina Kul, Emre Stork, Oliver Martínez-García, Fernando Nacher, Juan Lanuza, Enrique Santos, Mónica
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Published in
Brain Structure and Function
The protein doublecortin is mainly expressed in migrating neuroblasts and immature neurons. The X-linked gene MECP2, associated to several neurodevelopmental disorders such as Rett syndrome, encodes the protein methyl-CpG-binding protein 2 (MeCP2), a regulatory protein that has been implicated in neuronal maturation and refinement of olfactory circ...
Casas-Torremocha, Diana Porrero, César Rodriguez-Moreno, Javier García-Amado, María Lübke, Joachim H. R. Núñez, Ángel Clascá, Francisco
Published in
Brain Structure and Function
Rodents extract information about nearby objects from the movement of their whiskers through dynamic computations that are carried out by a network of forebrain structures that includes the thalamus and the primary sensory (S1BF) and motor (M1wk) whisker cortices. The posterior nucleus (Po), a higher order thalamic nucleus, is a key hub of this net...
Watanabe, Takashi Tan, Zhengguo Wang, Xiaoqing Martinez-Hernandez, Ana Frahm, Jens
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Brain Structure and Function
Noradrenaline is a neurotransmitter involved in general arousal, selective attention, memory, inflammation, and neurodegeneration. The purpose of this work was to delineate noradrenergic neurons in vivo by T1-weighted MRI with magnetization transfer (MT). In the brainstem of human and mice, MRI identified the locus coeruleus, dorsal motor vagus nuc...
Witt, Juri-Alexander Coras, Roland Becker, Albert J. Elger, Christian E. Blümcke, Ingmar Helmstaedter, Christoph
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Brain Structure and Function
Supraspan list learning tests are sensitive measures used to assess temporal lobe dysfunction. Most frequently employed is the Rey Auditory Verbal Learning and Memory Test (RAVLT). The test’s structure is determined by a short- and long-term memory component. During the first of five learning trials, the short-term memory component is the highest a...
Hauser, M. F. A. Wiescholleck, V. Colitti-Klausnitzer, J. Bellebaum, C. Manahan-Vaughan, Denise
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Brain Structure and Function
In the human cortex, event-related potentials (ERPs) are triggered in response to sensory, cognitive or motor stimuli. Due to the inherent difficulties of conducting invasive mechanistic studies in human subjects, little is known as to the precise neurophysiological mechanisms that lead to their manifestation. By contrast, although much is known ab...
Tissieres, Isabel Crottaz-Herbette, Sonia Clarke, Stephanie
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Brain Structure and Function
Spatial cues contribute to the ability to segregate sound sources and thus facilitate their detection and recognition. This implicit use of spatial cues can be preserved in cases of cortical spatial deafness, suggesting that partially distinct neural networks underlie the explicit sound localization and the implicit use of spatial cues. We addresse...
Sarubbo, Silvio Petit, Laurent De Benedictis, Alessandro Chioffi, Franco Ptito, Maurice Dyrby, Tim
Whether brain networks underlying the multimodal processing of language in humans are present in non-human primates is an unresolved question in primate evolution. Conceptual awareness in humans, which is the backbone of verbal and non-verbal semantic elaboration, involves intracerebral connectivity via the inferior fronto-occipital fascicle (IFOF)...
de Andrade Rufino, Rodrigo Mota-Ortiz, Sandra Regina De Lima, Miguel Antonio Xavier Baldo, Marcus Vinicius C. Canteras, Newton Sabino
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Brain Structure and Function
A few studies have evaluated the behavioral roles of the periaqueductal gray (PAG) in animals facing ethologically relevant threats. Exposure to a live cat induces striking activation in the rostrodorsal and caudal ventral PAG. In the present investigation, we first showed that cytotoxic lesions of the rostrodorsal and caudal ventral PAG had simila...
