A 22-Year Old Woman with Right Eyelid Swelling.
Published in Brain pathology (Zurich, Switzerland)
47-year-old man with left leg numbness.
Published in Brain pathology (Zurich, Switzerland)
A 47-year-old white male with a history of uveitis, hypercalcemia and nephrolithiasis presented with acute onset partial seizure. On exam he had decreased sensation to light touch on his left lower extremity. A Brain MRI revealed a right frontal mass, which was initially thought to be a metastatic lesion or a primary brain tumor. However, biopsy of...
Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of h...
Published in Brain pathology (Zurich, Switzerland)
Familial Danish dementia (FDD) is an autosomal dominant neurodegenerative disease clinically characterized by the presence of cataracts, hearing impairment, cerebellar ataxia and dementia. Neuropathologically, FDD is characterized by the presence of widespread cerebral amyloid angiopathy (CAA), parenchymal amyloid deposition and neurofibrillary tan...
71-year-old female with right eye proptosis.
Published in Brain Pathology
Meningiomas that arise outside the cranial vault without a dural connection comprise about 1–2% of all meningiomas and are referred to as primary extradural meningiomas (PEMs), intraosseous type 1. When these tumors occur within bone, they may be initially misinterpreted radiologically as a primary bone lesion.We report the case of a 71-year-old wo...
78 year old male with dysphagia and dysarthria.
Published in Brain Pathology
Genomic landscape of meningiomas.
...Published in Brain Pathology
Meningiomas are one of the most common adult brain tumors. For most patients, surgical excision is curative. However, up to 20% recur. Currently, the molecular determinants predicting recurrence and malignant transformation are lacking. We performed retrospective global genetic and genomic analysis of 85 meningioma samples of various grades. Copy n...
55-year-old female with low back pain.
Published in Brain Pathology
