Chen, Xinling Xu, Zhenhua Li, Ting Wang, Li Li, Peiyi Xu, Han Feng, Chunliang Liu, Chao
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Brain imaging and behavior
Need for closure (NFC) reflects stable individual differences in the desire for a quick, definite, and stable answer to a question. A large body of research has documented the association between NFC and various cognitive, emotional and social processes. Despite considerable interest in psychology, little effort has been made to uncover the neural ...
Meier, Erin L Kelly, Catherine R Goldberg, Emily B Hillis, Argye E
Published in
Brain imaging and behavior
In contrast to the traditional definition of the disorder, many individuals with aphasia exhibit non-linguistic cognitive impairments, including executive control deficits. Classic lesion studies cite frontal lobe damage in executive dysfunction, but more recent lesion symptom-mapping studies in chronic aphasia present mixed results. In this study,...
Grohs, Melody N Lebel, Catherine Carlson, Helen L Craig, Brandon T Dewey, Deborah
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Brain imaging and behavior
Developmental coordination disorder (DCD) is a neurodevelopmental disorder occurring in 5-6% of school-aged children. Converging evidence suggests that dysfunction within cortico-striatal and cortico-cerebellar networks may contribute to motor deficits in DCD, yet limited research has examined the brain morphology of these regions. Using T1-weighte...
Bangen, Katherine J Delano-Wood, Lisa Deoni, Sean C L Clark, Alexandra L Evangelista, Nicole D Hoffman, Samantha N Sorg, Scott F Holmqvist, Sophia Osuna, Jessica Weigand, Alexandra J
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Brain imaging and behavior
Alterations to cerebral white matter tracts have been associated with cognitive decline in aging and Alzheimer's disease (AD). In particular, the fornix has been implicated as especially vulnerable given that it represents the primary outflow tract of the hippocampus. Despite this, little work has focused on the fornix using a potential early marke...
Doorenweerd, Nathalie de Rover, Mischa Marini-Bettolo, Chiara Hollingsworth, Kieren G Niks, Erik H Hendriksen, Jos G M Kan, Hermien E Straub, Volker
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Brain imaging and behavior
Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder caused by absence of dystrophin protein. Dystrophin is expressed in muscle, but also in the brain. Difficulties with attention/inhibition, working memory and information processing are well described in DMD patients but their origin is poorly understood. The default m...
Dutt, Shubir Li, Yanrong Mather, Mara Nation, Daniel A
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Brain imaging and behavior
Neuropathological research suggests the tau pathology of Alzheimer's disease may originate in brainstem nuclei, yet it remains unknown whether tau-mediated degeneration of brainstem nuclei influences cognitive impairment in prodromal Alzheimer's disease. The present study examined cognitive domains impacted in prodromal Alzheimer's disease and brai...
Nicastro, Nicolas Mak, Elijah Surendranathan, Ajenthan Rittman, Timothy Rowe, James B O'Brien, John T
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Brain imaging and behavior
The impairment of large-scale brain networks has been observed in dementia with Lewy bodies (DLB) using functional connectivity, but the potential for an analogous effect on structural covariance patterns has not been determined. Twenty-four probable DLB subjects (mean age 74.3 ± 6.7 years, 16.7% female) and 23 similarly aged Controls were included...
Rutten, Geert-Jan M Landers, Maud J F De Baene, Wouter Meijerink, Tessa van der Hek, Stephanie Verheul, Jeroen H B
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Brain imaging and behavior
Direct electrical stimulation mapping was used to map executive functions during awake surgery of a patient with a right frontal low-grade glioma. We specifically targeted the frontal aslant tract, as this pathway had been infiltrated by the tumor. The right frontal aslant tract has been implicated in executive functions in the neuroscientific lite...
Schienle, Anne Wabnegger, Albert
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Brain imaging and behavior
An extremely bitter taste can signal food spoilage, and therefore typically elicits disgust. The present cross-modal functional magnetic resonance imaging experiment investigated whether the personality trait 'disgust propensity' (DP; temporally stable tendency to experience disgust across different situations) has an influence on the processing of...
Naef, Nadja Schlosser, Ladina Brugger, Peter Greutmann, Matthias Oxenius, Angela Wehrle, Flavia Kottke, Raimund Latal, Beatrice O'Gorman, Ruth Tuura
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Brain imaging and behavior
Congenital heart disease is the most common birth defect, and patients are at risk for neurodevelopmental impairment and brain abnormalities. Yet, little is known about the link between brain volumes and cognitive function in adults with congenital heart disease. Forty-four patients and 53 controls between 18 and 32 years underwent brain magnetic r...