Gonzalez-Escamilla, Gabriel Miederer, Isabelle Grothe, Michel J Schreckenberger, Mathias Muthuraman, Muthuraman Groppa, Sergiu
Published in
Brain imaging and behavior
Alzheimer's disease (AD) is a neurodegenerative disorder, considered a disconnection syndrome with regional molecular pattern abnormalities quantifiable by the aid of PET imaging. Solutions for accurate quantification of network dysfunction are scarce. We evaluate the extent to which PET molecular markers reflect quantifiable network metrics derive...
Zhang, Tuo Li, Xiao Jiang, Xi Ge, Fangfei Zhang, Shu Zhao, Lin Liu, Huan Huang, Ying Wang, Xianqiao Yang, Jian
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Published in
Brain imaging and behavior
Mapping the relation between cortical convolution and structural/functional brain architectures could provide deep insights into the mechanisms of brain development, evolution and diseases. In our previous studies, we found a unique gyral folding pattern, termed a 3-hinge, which was defined as the conjunction of three gyral crests. The uniqueness o...
Yu, Junhong Lee, Tatia M C
Published in
Brain imaging and behavior
While strong cross-sectional evidence supported the use of fornix microstructure as a marker for detecting Alzheimer's disease (AD), longitudinal data remains inconclusive on the sequential nature of fornix microstructure abnormalities and AD progression. An unequivocal longitudinal relationship between fornix microstructure and markers of AD progr...
De Baene, Wouter Jansma, Martijn J Schouwenaars, Irena T Rutten, Geert-Jan M Sitskoorn, Margriet M
Published in
Brain imaging and behavior
In healthy participants, the strength of task-evoked network reconfigurations is associated with cognitive performance across several cognitive domains. It is, however, unclear whether the capacity for network reconfiguration also plays a role in cognitive deficits in brain tumor patients. In the current study, we examined whether the level of reco...
Fernandes, Orlando Jr Portugal, Liana Catrina Lima Alves, Rita de Cássia S. Arruda-Sanchez, Tiago Volchan, Eliane Pereira, Mirtes Garcia Mourão-Miranda, Janaina Oliveira, Letícia
Published in
Brain Imaging and Behavior
Whether subtle differences in the emotional context during threat perception can be detected by multi-voxel pattern analysis (MVPA) remains a topic of debate. To investigate this question, we compared the ability of pattern recognition analysis to discriminate between patterns of brain activity to a threatening versus a physically paired neutral st...
Zhuo, Chuanjun Ji, Feng Lin, Xiaodong Tian, Hongjun Wang, Lina Liu, Sha Sang, Hong Wang, Wenqiang Chen, Chunmian
Published in
Brain imaging and behavior
Few studies have reported on brain functional differences between healthy individuals with auditory verbal hallucinations (Hi-AVH) with and without insight, so we designed a study to address this knowledge gap. We enrolled 12 Hi-AVH with insight, 15 Hi-AVH without insight, and 15 AVH-free controls (Healthy controls). Global functional connectivity ...
van Zutphen, Linda Siep, Nicolette Jacob, Gitta A Domes, Gregor Sprenger, Andreas Willenborg, Bastian Goebel, Rainer Tüscher, Oliver Arntz, Arnoud
Published in
Brain imaging and behavior
Impulsivity is a characteristic syndromal and neurobehavioral feature of borderline personality disorder (BPD). Research suggests an important interaction between high negative emotions and low behavioral inhibition in BPD. However, knowledge about the generalizability across stimulus categories and diagnosis specificity is limited. We investigated...
Fathy, Yasmine Y Hoogers, Susanne E Berendse, Henk W van der Werf, Ysbrand D Visser, Pieter J de Jong, Frank J van de Berg, Wilma D J
Published in
Brain imaging and behavior
The insular cortex is proposed to function as a central brain hub characterized by wide-spread connections and diverse functional roles. As a result, its centrality in the brain confers high metabolic demands predisposing it to dysfunction in disease. However, the functional profile and vulnerability to degeneration varies across the insular sub-re...
Michielse, Stijn Lange, Iris Bakker, Jindra Goossens, Liesbet Verhagen, Simone Wichers, Marieke Lieverse, Ritsaert Schruers, Koen van Amelsvoort, Therese van Os, Jim
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Published in
Brain imaging and behavior
Group comparisons of individuals with psychotic disorder and controls have shown alterations in white matter microstructure. Whether white matter microstructure and network connectivity is altered in adolescents with subclinical psychotic experiences (PE) at the lowest end of the psychosis severity spectrum is less clear. DWI scan were acquired in ...
Brugulat-Serrat, Anna Salvadó, Gemma Sudre, Carole H Grau-Rivera, Oriol Suárez-Calvet, Marc Falcon, Carles Sánchez-Benavides, Gonzalo Gramunt, Nina Fauria, Karine Cardoso, M Jorge
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Published in
Brain imaging and behavior
White matter hyperintensities (WMH) are commonly detected in the brain of elderly individuals and have been associated with a negative impact on multiple cognitive domains. We aim to investigate the impact of global and regional distribution of WMH on episodic memory and executive function in middle-aged cognitively unimpaired participants [N = 561...
