Bilgic, S Armagan, I
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated the potential nephroprotective effects of misoprostol (MP) on doxorubicin (DOX) induced renal injury using histologic and biochemical assessment of rat kidneys. We used 21 male rats divided into three groups: group 1, control; group 2, DOX; group 3, DOX + MP. The control group was given 0.5 ml 0.9% NaCl and 1 ml 0.9% NaCl orally for...
Sağır, D Kuruoğlu, E Onger, M E Yarar, E
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Peripheral nerve injury creates unusual sensitivity and pathological spontaneous activity in neurons that are described as ectopic discharge. Voltage dependent Na channels are responsible for ectopic discharge. Topiramate (TOP) inhibits voltage-gated sodium channels by blocking both the amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)/kai...
Cortés-Gutiérrez, E I García-Vielma, C Dávila-Rodríguez, M I Sánchez-Dávila, H Fernández, J L Gosálvez, J
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated the association between progressive stages of cervical neoplasia and DNA damage in 1p36 DNA sequences of chromosome 1 in cervical epithelium using DNA breakage detection/fluorescence in situ hybridization (DBD-FISH). We used a hospital based unmatched case control study of 29 women that were grouped according to disease stage and se...
Ozer, M K Bilgic, S Armagan, I Savran, M
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated whether thymoquinone (TQ) exerts a beneficial effect on renal injury due to amikacin (AK) administration in rats. To generate kidney damage with AK, a single 1.2 g/kg dose of AK was administered intraperitoneally. TQ was administered orally to the AK treated group at a dose of 40 mg/kg for five days. At the end of the experiment, ra...
Aydin, S Kuloglu, T Aydin, Y Yalcin, M H Ugur, K Albayrak, S Aksoy, A Sahin, I Dagli, A F Akkoc, R F
...
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Despite significant advances in medicine, mortality due to cardiovascular disease is not yet preventable. We investigated the amounts of elabela (ELA) and apelin, synthesized by cardiomyocytes, and changes of these compounds in cardiac tissue and circulation after administration of iloprost (ILO) and sildenafil (SIL) in rats with induced myocardial...
Bonacho, T Rodrigues, F Liberal, J
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Breast cancer is the most prevalent malignant tumor and main oncologic cause of mortality in women. Although most diagnosis of breast pathology is accomplished using hematoxylin and eosin stained sections, some cases require immunohistochemistry for proper evaluation. We investigated the latter cases including distinctions between ductal and lobula...
Ünsal, Ülkün Ünlü Mete, Mesut Aydemir, Işil Duransoy, Yusuf Kurtuluş Umur, Ahmet Şükrü Tuglu, Mehmet Ibrahim
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated the potential anticancer effects of oleocanthal (OC) on neuroblastoma cells. Cells were divided into four groups: group 1, neuroblastoma cells were treated with OC; group 2, neurons that differentiated from neuroblastoma cells were treated with phosphate-buffered saline(PBS); group 3, bone marrow derived neuronal (BMDN) cells that w...
Gruber, H E Marrero, E Cox, M Hanley, Edward Jr
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Interleukin-23 (IL-23, IL-23p19) is a proinflammatory cytokine in the IL-12-related family. Although inflammatory cells in herniated discs have been shown to contain IL-23, little is known about the presence and role of IL-23 in human disc cells. We analyzed disc specimens for IL-23 localization using immunohistochemistry in control, herniated and ...
Schurink, B Cleypool, C G J Bleys, R L A W
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Milky spots are unique lymphoid structures in the greater omentum that participate in both immune homeostasis of the peritoneal cavity and formation of omental metastases. We developed a rapid and simple staining method to enable macro- or stereomicroscopic identification of these miniscule structures in large samples of fixed human greater omentum...
Redman, R S Bayley, N C Nylén, E S
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
A peripheral (gingival) fibroma, a gingival cyst and hyperplastic gingivitis occurred simultaneously in a man with metastatic medullary thyroid carcinoma (MCT). The gingival growths and hyperplasia appeared to be related to poor oral hygiene rather than to the MTC. Despite the patient's improved oral hygiene, the hyperplastic gingivitis and periphe...
