Cavdar, Zahide Oktan, Mehmet Asi Ural, Cemre Kocak, Ayse Calisir, Meryem Heybeli, Cihan Yildiz, Serkan Ozbal, Seda Arslan, Sevki Ergur, Bekir Ugur
...
Published in
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Iron has been implicated in oxidative tissue injury owing to its ability to generate reactive oxygen species (ROS). We investigated the reno-protective effects of alpha lipoic acid (ALA) by investigating its effects on the kidney isoform of NADPH oxidase (Nox4) and the specific signaling pathways, p38 MAPK and PI3K/Akt, which participate in apoptos...
Sözmen, M Devrim, A K Sudağıdan, M Kabak, Y B Yıldırım, F
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Skin and subcutaneous tissue tumors are the most common neoplasms in dogs. The most common sites of origin in dogs include digits, skin and the oral cavity including cheek and retromandibular area. We investigated canine squamous cell carcinoma (SCC) samples from 15 dogs and classified them histopathologically according to the degree of differentia...
Ünver Saraydin, Serpil Özdenoglu Kutlu, Berna Saraydın, Dursun
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Diabetes contributes to neurological dysfunction including peripheral nerve diseases, stroke and dementia. We investigated the effects of diabetes on apoptosis and mitosis in the hippocampal CA1 region. Rats were given diabetes by injection of streptozotocin (STZ). The mass and blood glucose levels of the rats were measured until day 7 of the exper...
Korkmaz Ağaoğlu, Özgecan Ağaoğlu, Ali Reha Özmen, Özlem Saatci, Mustafa Schäfer-Somi, Sabine Aslan, Selim
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Members of the IGF gene family participate in cell differentiation and proliferation during pregnancy. We used 35 cats assigned to experimental groups (G) based on pregnancy stages: G1, pre-implantation; G2, implantation; G3, early pregnancy; G4, mid-pregnancy; G5, nonpregnant. Quantitative polymerase chain reaction (qPCR) and immunohistochemistry ...
Abdel Halim, Alyaa S Ahmed, Hanaa H Aglan, Hadeer A Abdel Hamid, Fatma F Mohamed, Mohamed R
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
The therapeutic role of mesenchymal stem cells (MSCs) in cases of amiodarone (AD) induced pulmonary fibrosis (PF) has not been well studied. Also, the period required by MSCs to attain full therapeutic effectiveness has not yet been assessed. We investigated the potential curative effect of bone marrow-derived MSCs (BM-MSCs) and conditioned media (...
Santos, Laís Caroline da Silva Lapa Neto, Clovis José Cavalcanti Santos, Anthony Marcos Gomes Dos Marinho, Ketsia Sabrina do Nascimento Nascimento, Bruno José do Alves, Erique Ricardo Teixeir, Álvaro Aguiar Coelho Wanderley-Teixeira, Valéria
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated possible changes in morphology and immunohistochemistry of the uterus and ovaries of rats caused by nandrolone (ND); we also investigated effects on fertility. We used 30 rats divided into three experimental groups: control (C), control vehicle (CV) and 5 mg/kg ND. Rats treated with ND exhibited loss of estrous cyclicity with predom...
Vurmaz, A Ertekin, A Sabaner, M Cem Atay, E Bozkurt, E Bilir, A
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
We investigated the antioxidant effects of vitamin E on a glucocorticoid (GC) induced model of cataracts in chick embryos. We used 70 fertilized eggs divided into seven groups as follows: phosphate-buffered saline (PBS) group, olive oil treatment (OO) group, hydrocortisone treatment (HC) group, olive oil and hydrocortisone treatment (OO + HC) group...
Karabulut, Derya Sonmez, Mehmet Fatih
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Diabetes mellitus (DM) is a common metabolic disorder with complications including nephropathy, cardiomyopathy, neuropathy and infertility. We investigated nitric oxide synthase (NOS) expression in uterine tissue of diabetic rats. The rats were assigned randomly to four groups of ten: group C, control; group 1, diabetic for 1 month; group 2, diabet...
Uppada, Srijayaprakash B Madduri, Lepakshi S V Singu, Sravani Lawson, Brooke Bauer, Linda Freifeld, Alison Bhatt, Vijaya R Byrareddy, Siddappa N
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Pathologists collect swab samples for Papanicolaou (Pap) staining to diagnose various diseases including cancer and HIV. Time constraints and limited resources, may preclude staining a sample immediately. To re-confirm results, samples must be frozen for later analysis. We present a method for Pap staining cells that have been stored long term. An ...
Koc Yildirim, Ece Balkaya, Muharrem
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Biotechnic & histochemistry : official publication of the Biological Stain Commission
Reports of the effects of calorie restriction on tumors after the tumor has developed are uncommon and limited to a few tumor types. We investigated the effects of calorie restriction on tumor growth in breast cancer after tumor growth had progressed. We used the N-nitroso-N-methylurea (NMU) induced breast cancer model in rats. In addition to a hea...
