Wang, Fei Yang, Jun He, Ruyi Yu, Xiao Chen, Shuliang Liu, Yang Wang, Longyu Li, Aitao Liu, Linlin Zhai, Chao
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Biosensors & bioelectronics
In the present study, we upgraded Pyrococcus furiosus Argonaute (PfAgo) mediated nucleic acid detection method and established a highly sensitive and accurate molecular diagnosis platform for the large-scale screening of COVID-19 infection. Briefly, RT-PCR was performed with the viral RNA extracted from nasopharyngeal or oropharyngeal swabs as temp...
Ahmadivand, Arash Gerislioglu, Burak Ramezani, Zeinab Kaushik, Ajeet Manickam, Pandiaraj Ghoreishi, S Amir
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Biosensors & bioelectronics
Effective and efficient management of human betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 virus infection i.e., COVID-19 pandemic, required sensitive and selective sensors with short sample-to-result durations for performing desired diagnostics. In this direction, one appropriate alternative approach to detect SARS-CoV-2 virus prot...
Ghodake, Gajanan Sampatrao Shinde, Surendra Krushna Kadam, Avinash Ashok Saratale, Rijuta Ganesh Saratale, Ganesh Dattatraya Syed, Asad Elgorban, Abdallah M Marraiki, Najat Kim, Dae-Young
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Biosensors & bioelectronics
Existing coronavirus named as a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has speeded its spread across the globe immediately after emergence in China, Wuhan region, at the end of the year 2019. Different techniques, including genome sequencing, structural feature classification by electron microscopy, and chest imaging using com...
Chang, Yaran Chen, Yongjia Shao, Yunlong Li, Boye Wu, Yuanyuan Zhang, Wenmei Zhou, Yingyan Yu, Zhihui Lu, Liping Wang, Xiayan
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Biosensors & bioelectronics
Dopamine participates in many physiological and pathological processes. Dynamic monitoring of dopamine levels in the cytoplasm of a single living cell reflects not only the functional state of dopamine synthesis factors but also the processes of related neurodegenerative diseases. Due to the low content of cytoplasmic dopamine and the difficulty to...
Jiang, Lei Wang, Lu Zhan, De-Sheng Jiang, Wen-Rong Fodjo, Essy Kouadio Hafez, Mahmoud Elsayed Zhang, Yan-Mei Zhao, Hu Qian, Ruo-Can Li, Da-Wei
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Biosensors & bioelectronics
The accurate detection of hydrogen peroxide (H2O2)-involved metabolites plays a significant role in the early diagnosis of metabolism-associated diseases, whereas most of current metabolite-sensing systems are often hindered by low sensitivity, interference of coexisting species, or tedious preparation. Herein, an electrochemistry-regenerated surfa...
Zhou, Lanlan Zhang, Linling Yang, Liu Ni, Wei Li, Yong Wu, Yunhua
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Biosensors & bioelectronics
Detection of dysregulated circulating microRNAs (miRNAs) in human biofluids is a fundamental ability to determine tumor occurrence and metastasis in a minimally invasive fashion. However, the requirements for sophisticated instruments and professional personnel impede the translation of miRNA tests into routine clinical diagnostics, especially for ...
Li, Lang Wang, Zhuyuan Lu, Yang Zhu, Kai Zong, Shenfei Cui, Yiping
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Biosensors & bioelectronics
Nanostructure with precisely controllable narrow gap width remains a great challenge, especially at the sub-nanoscale level. Here, a versatile strategy named as DNA-assisted synthesis of ortho-nanodimer (DaSON) is proposed to fabricate Ag (Au) nanodimers with a uniform gap width from nanometers to angstroms. In such a strategy, two nanoparticles ar...
Shumeiko, Vlad Paltiel, Yossi Bisker, Gili Hayouka, Zvi Shoseyov, Oded
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Biosensors & bioelectronics
Electronic noses (e-nose) and optical noses (o-nose) are two emerging approaches for the development of artificial olfactory systems for flavor and smell evaluation. The current work leverages the unique optical properties of semiconducting single-wall carbon nanotubes (SWCNTs) to develop a prototype of a novel paper-based near-infrared optical nos...
Rebelo, Patrícia Costa-Rama, Estefanía Seguro, Isabel Pacheco, João G Nouws, Henri P A Cordeiro, M Natália D S Delerue-Matos, Cristina
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Biosensors & bioelectronics
The ever-increasing presence of contaminants in environmental waters is an alarming issue, not only because of their harmful effects in the environment but also because of their risk to human health. Pharmaceuticals and pesticides, among other compounds of daily use, such as personal care products or plasticisers, are being released into water bodi...
Baradoke, Ausra Santos, Adriano Bueno, Paulo R Davis, Jason J
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Biosensors & bioelectronics
In this work we demonstrate that an impedance derived capacitance method is able to cleanly resolve the resonant conductance characteristics of an electrode-confined polymer film. In decorating the film with receptors, this conductance is thereafter modulated by the capturing of specific targets, demonstrated herein with C-reactive protein. This en...