Boutzen, Jocelyn Valet, Manon Alviset, Agathe Fradot, Valérie Rousseau, Lionel Français, Olivier Picaud, Serge Lissorgues, Gaëlle
Published in
Biosensors & bioelectronics
In age-related macular degeneration, the retinal pigment epithelium can be damaged by light acting on photosensitizers like N-retinylidene-N-retinylethanolamine (A2E). In this paper, the underlying cellular mechanism of lesion at the cell layer scale is analyzed by impedance spectroscopy. Retinal pigment epithelium (RPE) cells are cultured on top o...
Huang, Chi-Hsien Huang, Tzu-Ting Chiang, Chia-Heng Huang, Wei-Ting Lin, Yi-Ting
Published in
Biosensors & bioelectronics
In this study we developed a uniform, large-area, layered graphene composite of graphene oxide/graphene (GO/G) for the detection of circulating miRNA-21, a reliable biomarker for early cancer diagnosis. We prepared this layered composite of GO/G through low-damage plasma treatment of bilayer G. The top layer of G was oxidized (i.e., atomic layer ox...
Kim, Hyunsoo Park, Jong Woo Hyeon, Jae Sang Sim, Hyeon Jun Jang, Yongwoo Shim, Yujin Huynh, Chi Baughman, Ray H Kim, Seon Jeong
Published in
Biosensors & bioelectronics
Various studies about harvesting energy for future energy production have been conducted. In particular, replacing batteries in implantable medical devices with electrical harvesting is a great challenge. Here, we have improved the electrical harvesting performance of twisted carbon nanotube yarn, which was previously reported to be an electrical e...
Han, Rui Wang, Guixiang Xu, Zhenying Zhang, Leyao Li, Qun Han, Yinfeng Luo, Xiliang
Published in
Biosensors & bioelectronics
An antifouling electrochemical biosensing platform was constructed based on conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) planted with designed peptides. The designed peptides containing doping and antifouling sequences were anchored to an electrode surface, followed by the electrochemical polymerization of PEDOT. The negatively charg...
Li, Nan-Si Chen, Ying-Tzu Hsu, Ying-Pei Pang, Hao-Han Huang, Chiung-Yin Shiue, Yow-Ling Wei, Kuo-Chen Yang, Hung-Wei
Published in
Biosensors & bioelectronics
Excessive production of uric acid (UA) in blood may lead to gout, hyperuricaemia and kidney disorder; thus, a fast, simple and reliable biosensor is needed to routinely determine the UA concentration in blood without pretreatment. The purpose of this study was to develop a mobile healthcare (mHealth) system using a drop of blood, which comprised a ...
Huang, Jiayu Meng, Jian Chen, Shaohua Zhang, Siyi Liu, Tao Li, Chao Wang, Feng
Published in
Biosensors & bioelectronics
Herein, we have proposed a soft metal-phenolic capsule (sMPC)-based electrochemical immunoassay for ultrasensitive detection of Epstein-Barr virus capsid antigen IgA (EBVCA-IgA), a biomarker of nasopharyngeal carcinoma. Metal probes with large size contain a number of metal ions, which are very beneficial to signal amplification for anodic strippin...
Guo, Shuang Xu, Jie Estell, Alexander Pettit Ivory, Cornelius F Du, Dan Lin, Yuehe Dong, Wen-Ji
Published in
Biosensors & bioelectronics
Exosomes derived from cancer cells/tissues have great potential for early cancer diagnostic use, but their clinical potential has not been fully explored because of a lack of cost-effective multiplex approaches capable of effectively isolating and identifying specific exosome populations and analyzing their content biomarkers. This study was aimed ...
Golabchi, Asiyeh Woeppel, Kevin M Li, Xia Lagenaur, Carl F Cui, X Tracy
Published in
Biosensors & bioelectronics
Intracortical microelectrodes are being developed to both record and stimulate neurons to understand brain circuitry or restore lost functions. However, the success of these probes is hampered partly due to the inflammatory host tissue responses to implants. To minimize the foreign body reactions, L1, a brain derived neuronal specific cell adhesion...
Stoian, Ioan-Adrian Iacob, Bogdan-Cezar Dudaș, Cosmina-Larisa Barbu-Tudoran, Lucian Bogdan, Diana Marian, Iuliu Ovidiu Bodoki, Ede Oprean, Radu
Published in
Biosensors & bioelectronics
A highly selective and sensitive molecularly imprinted polymer (MIP)-based electrochemical sensor was fabricated for the determination of azithromycin, a broad-spectrum macrolide antibiotic, from various biological samples (urine, tears, plasma). The reversible boronate ester bond-mediated, thin (~75 nm) MIP-based biomimetic recognition layer was e...
Yu, Ziqing Lyu, Weiyuan Yu, Mengchao Wang, Qian Qu, Haijun Ismagilov, Rustem F Han, Xu Lai, Dongmei Shen, Feng
Published in
Biosensors & bioelectronics
Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide, and persistent HPV infection can cause warts and even cancer. Nucleic acid analysis of HPV viral DNA can be very informative for the diagnosis and monitoring of HPV. Digital nucleic acid analysis, such as digital PCR and digital isothermal amplification,...
