Zhang, Kai Fan, Zhenqiang Ding, Yuedi Li, Jinlong Li, Hao
Published in
Biosensors & bioelectronics
The poor situational awareness about the spreading of the virus especially in the underdeveloped regions calls for novel virus assays of low cost and simple operation. Currently, such assays are exclusively restricted to nucleic acid detection. In this investigation, a virus protein serum assay has been proposed in a one-step and reagent-less route...
Ding, Shichao Lyu, Zhaoyuan Li, Suiqiong Ruan, Xiaofan Fei, Mingen Zhou, Yang Niu, Xiangheng Zhu, Wenlei Du, Dan Lin, Yuehe
...
Published in
Biosensors & bioelectronics
An electrochemical sensor based on molecularly imprinted polypyrrole nanotubes (MIPNs) has been developed for the detection of glyphosate (Gly) with high sensitivity and specificity. Herein, the MIPNs are prepared by imprinting Gly sites on the surface of polypyrrole (PPy) nanotubes. The synthesized MIPNs have high electrical conductivity and exhib...
Ju, Yong Kim, Jaemin Park, Yeonkyung Lee, Chang Yeol Kim, Kyungnam Hong, Ki Ho Lee, Hyukmin Yong, Dongeun Park, Hyun Gyu
Published in
Biosensors & bioelectronics
We herein describe rapid and accurate clinical testing for COVID-19 by nicking and extension chain reaction system-based amplification (NESBA), an ultrasensitive version of NASBA. The primers to identify SARS-CoV-2 viral RNA were designed to additionally contain the nicking recognition sequence at the 5'-end of conventional NASBA primers, which wou...
Zhou, Shirong Li, Xuejin Zhang, Jinghan Yuan, Hao Hong, Xueming Chen, Yuzhi
Published in
Biosensors & bioelectronics
The rapid and accurate detection of triglyceride (TG) plays a valuable role in the prevention and control of dyslipidemia. In this paper, a novel method for TG detection using a dual-fiber optic bioprobe system, which can accurately detect different levels of TG concentration in serum, is proposed. The system employs disposable microprobe-type fibe...
Qian, Jingjing Zhang, Qinming Liu, Mingdian Wang, Yixuan Lu, Meng
Published in
Biosensors & bioelectronics
Exosomal microRNAs (miRNAs) play a key role in cell-cell communication to regulate gene expression in target cells and have great potential as biomarkers for disease diagnosis. This paper reports an on-chip exosomal miRNA amplification and detection system for rapid analysis of exosomal miRNAs. The compact system consists of two connected flow cell...
Viehauser, Marie-Christin Breslmayr, Erik Scheiblbrandner, Stefan Schachinger, Franziska Ma, Su Ludwig, Roland
Published in
Biosensors & bioelectronics
The development of third generation biosensors depends on the availability of direct electron transfer (DET) capable enzymes. A successful strategy is to fuse a cytochrome domain to an enzyme to fulfil the function of a built-in redox mediator between the catalytic center and the electrode. In this study, we fused the cytochrome domain of Neurospor...
Ferrara, Francesco Zoupanou, Sofia Primiceri, Elisabetta Ali, Zulfiqur Chiriacò, Maria Serena
Published in
Biosensors & bioelectronics
Liquid biopsy technologies have seen a significant improvement in the last decade, offering the possibility of reliable analysis and diagnosis from several biological fluids. The use of these technologies can overcome the limits of standard clinical methods, related to invasiveness and poor patient compliance. Along with this there are now mature e...
Wang, Qiuping Chen, Min Xiong, Can Zhu, Xiaofei Chen, Cai Zhou, Fangyao Dong, Yun Wang, Yu Xu, Jie Li, Yimin
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Published in
Biosensors & bioelectronics
The intrinsically fragile nature and leakage of the enzymes is a major obstacle for the commercial sensor of a continuous glucose monitoring system. Herein, a dual confinement effect is developed in a three dimensional (3D) nanocage-based zeolite imidazole framework (NC-ZIF), during which the high-loading enzymes can be well encapsulated with unusu...
Loyez, Médéric DeRosa, Maria C Caucheteur, Christophe Wattiez, Ruddy
Published in
Biosensors & bioelectronics
Optical fiber biosensors have attracted growing interest over the last decade and quickly became a key enabling technology, especially for the detection of biomarkers at extremely low concentrations and in small volumes. Among the many and recent fiber-optic sensing amenities, aptamers-based sensors have shown unequalled performances in terms of ea...
Zhu, Yongfeng Tong, Xia Wei, Qisheng Cai, Guihan Cao, Yuanxin Tong, Chaoying Shi, Shuyun Wang, Fang
Published in
Biosensors & bioelectronics
On-site multiplex enzyme detection is crucial for diagnosis, therapeutics and prognostic. To date, it is still a daunting challenge to develop portable, low-cost, and efficient multi-enzyme detection methods. Herein, a novel sample-in-result-out platform integrating ratiometric fluorescent assays with 3D origami microfluidic paper-based device (μPA...
