Shi, Lei Wang, Jinjia Wang, Xiaolong Zhang, Yuanxing Song, Zhiwei Cai, Menghao Zhou, Xiangshan
Published in
Bioresources and Bioprocessing
To explore the differences in the intracellular transcriptional mechanism in carbon-derepressed and wild-type Pichia pastoris strains fed with three different carbon sources. RNA in carbon-derepressed (Δmig1Δmig2Δnrg1-Mit1; Mut) and wild-type (WT) P. pastoris fed with three different carbon sources (dextrose, glycerol, and methanol) were sequenced....
Manan, Musaalbakri Abdul Webb, Colin
Published in
Bioresources and Bioprocessing
BackgroundThe growth of Aspergillus awamori and Aspergillus oryzae in a self-designed, multi-stacked circular tray solid-state bioreactor (SSB), operating in solid-state fermentation (SSF) conditions at a laboratory scale, was studied. The bioreactor was divided into six layers by six circular perforated trays. Wheat bran was used as both a carrier...
Xu, Jianlin Rehmann, Matthew S. Xu, Mengmeng Zheng, Shun Hill, Charles He, Qin Borys, Michael C. Li, Zheng Jian
Published in
Bioresources and Bioprocessing
The goal of cell culture process intensification is to increase volumetric productivity, generally by increasing viable cell density (VCD), cell specific productivity or production bioreactor utilization in manufacturing. In our previous study, process intensification in fed-batch production with higher titer or shorter duration was demonstrated by...
Wang, Jianfei Huang, Jiaqi Laffend, Hannah Jiang, Shaoming Zhang, Jing Ning, Yuchen Fang, Mudannan Liu, Shijie
Published in
Bioresources and Bioprocessing
Parametric optimization is an effective way in fermentation process to improve product yield and productivity in order to save time, space and financial resources. In this study, Box–Behnken design was applied to optimize the conditions for lactic acid production by immobilized Lactobacillus pentosus ATCC 8041 cell fermentation. Two quadratic model...
Sahu, Mahendra Kumar Kaushik, Komal Das, Amitava Jha, Harit
Published in
Bioresources and Bioprocessing
The present study evaluated the potential biological activities of rhizospheric fungi isolated from the Achanakmar Biosphere Reserve, India. Fungus, Talaromyces purpureogenus isolate-ABRF2 from the soil of the Achanakmar biosphere was characterized by using morphological, biochemical and molecular techniques. Fungus was screened for the production ...
Santos, Marcela Colombo dos Mendonça, Mayra de Lima Bicas, Juliano Lemos
Published in
Bioresources and Bioprocessing
Bikaverin is a fungal red pigment that presents antimicrobial and antitumor activities. Therefore, this substance could be used as an alternative additive in the food and pharmaceutical industries. The aim of this work was to use response surface methodology to optimize the fermentation conditions and maximize the production of bikaverin in shake f...
Qiao, Lijia Li, Xiaobo Ke, Xiang Chu, Ju
Published in
Bioresources and Bioprocessing
BackgroundSaccharopolyspora erythraea (S. erythraea) is a Gram-positive bacterium widely used for the production of erythromycin, a potent macrolide antibiotic. However, the mechanism behind erythromycin production is poorly understood. In the high erythromycin-producer strain S. erythraea HL3168 E3, the level of copper ions positively correlates w...
Zhou, Xiaoli Zhu, Honghui
Published in
Bioresources and Bioprocessing
Renewable biomass such as cellulose and chitin are the most abundant sustainable sources of energy and materials. However, due to the low degradation efficiency of these recalcitrant substrates by conventional hydrolases, these biomass resources cannot be utilized efficiently. In 2010, the discovery of lytic polysaccharide monooxygenases (LPMOs) le...
Jaisi, Amit Panichayupakaranant, Pharkphoom
Published in
Bioresources and Bioprocessing
The simultaneous and sequential dual elicitation effect on plumbagin production in Plumbago indica L. root cultures, revealed that combination of chitosan (150 mg L−1) with ʟ-alanine (5 mM) or methyl-β-cyclodextrin (MCD; 2 mM) significantly increased plumbagin production, but in the different treatment manners. The simultaneous treatment using chit...
Chopra, Sunil Kumar, Dharmender
Published in
Bioresources and Bioprocessing
BackgroundIn this study, the biodegradation of N-acetyl-para-aminophenol also known as acetaminophen (APAP, paracetamol) was studied by bacterial strain Bacillus drentensis strain S1 (accession no. KY623719) isolated from sewage sample.ResultsThe Bacillus drentensis strain S1 was isolated from the sewage sample using the enrichment culture method. ...
