Cheng, Chibin Seen, Daniel Zheng, Chunwen Zeng, Ruijie Li, Enmin
Published in
Biomolecules
Accumulating evidence has suggested a role of the small GTPase Ras homolog gene family member A (RhoA) in DNA damage response (DDR) in addition to its traditional function of regulating cell morphology. In DDR, 2 key components of DNA repair, ataxia telangiectasia-mutated (ATM) and flap structure-specific endonuclease 1 (FEN1), along with intracell...
Noh, YuJin Lee, Hwanhui Kim, Myeongsun Hong, Seong-Joo Lee, Hookeun Kim, Dong-Myung Cho, Byung-Kwan Lee, Choul-Gyun Choi, Hyung-Kyoon
Published in
Biomolecules
Synechocystis strains are cyanobacteria that can produce useful biomaterials for biofuel and pharmaceutical resources. In this study, the effects of exogenous glucose (5-mM) on cell growth, photosynthetic pigments, metabolites, and lipids in Synechocystis sp. PCC 7338 (referred to as Synechocystis 7338) were investigated. Exogenous glucose increase...
Kowalska, Małgorzata Turek, Paweł Żbikowska, Anna Babut, Monika Szakiel, Jerzy
Published in
Biomolecules
The study investigated the quality of emulsions containing rabbit fat modified with vegetable oil. The modification of the fat and introducing it as a fatty base into the emulsion was dictated by consumer preferences. Emulsion systems containing various fatty bases and viscosity modifier contents were evaluated in the terms of their stability (by m...
Féral, Kelly Jaud, Manon Philippe, Céline Di Bella, Doriana Pyronnet, Stéphane Rouault-Pierre, Kevin Mazzolini, Laurent Touriol, Christian
Published in
Biomolecules
The unfolded protein response (UPR) is an evolutionarily conserved adaptive signaling pathway triggered by a stress of the endoplasmic reticulum (ER) lumen compartment, which is initiated by the accumulation of unfolded proteins. This response, mediated by three sensors-Inositol Requiring Enzyme 1 (IRE1), Activating Transcription Factor 6 (ATF6), a...
Wang, Li Eom, Kilho Kwon, Taeyun
Published in
Biomolecules
Self-aggregation of amyloid-β (Aβ) peptides has been known to play a vital role in the onset stage of neurodegenerative diseases, indicating the necessity of understanding the aggregation process of Aβ peptides. Despite previous studies on the aggregation process of Aβ peptides, the aggregation pathways of Aβ isoforms (i.e., Aβ40 and Aβ42) and thei...
Perveen, Kahkashan Husain, Fohad Mabood Qais, Faizan Abul Khan, Altaf Razak, Suhail Afsar, Tayyaba Alam, Pravej Almajwal, Ali M Abulmeaty, Mahmoud M A
Published in
Biomolecules
Green synthesis of metal nanoparticles using plant extracts as capping and reducing agents for the biomedical applications has received considerable attention. Moreover, emergence and spread of multidrug resistance among bacterial pathogens has become a major health concern and lookout for novel alternative effective drugs has gained momentum. In c...
Sun, Hao Su, Xiaojuan Huang, Lingyi Mu, Dezhi Qu, Yi
Published in
Biomolecules
The epidemic due to the novel coronavirus (SARS-CoV-2) is now a global concern, posing a severe threat to the health of populations. At present, all countries in the world are stepping up the development of vaccines and antiviral agents to prevent the infection and further transmission of SARS-CoV-2. An in-depth investigation of the target organs a...
Biello, Federica Platini, Francesca D’Avanzo, Francesca Cattrini, Carlo Mennitto, Alessia Genestroni, Silvia Martini, Veronica Marzullo, Paolo Aimaretti, Gianluca Gennari, Alessandra
...
Published in
Biomolecules
Background: Breast cancer (BC) is the most common neoplasm in women. Many clinical and preclinical studies investigated the possible relationship between host metabolism and BC. Significant differences among BC subtypes have been reported for glucose metabolism. Insulin can promote tumorigenesis through a direct effect on epithelial tissues or indi...
Oksenych, Valentyn Kainov, Denis E.
Published in
Biomolecules
Braga, Susana Santos
Published in
Biomolecules