Unni, Sruthi Aouti, Snehal Thiyagarajan, Saravanamuthu Padmanabhan, Balasundaram
Published in
Journal of Biosciences
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is an emerging new viral pathogen that causes severe respiratory disease. SARS-CoV-2 is responsible for the outbreak of COVID-19 pandemic worldwide. As there are no confirmed antiviral drugs or vaccines currently available for the treatment of COVID-19, discovering potent inhibitors or vacc...
Yathavan, Bhuvanesh Chhibber, Tanya Steinhauff, Douglas Pulsipher, Abigail Alt, Jeremiah A Ghandehari, Hamidreza Jafari, Paris
Published in
Pharmaceutics
Chronic rhinosinusitis (CRS) is a chronic health condition affecting the sinonasal cavity. CRS-associated mucosal inflammation leads to sinonasal epithelial cell death and epithelial cell barrier disruption, which may result in recurrent bacterial infections and biofilm formation. For patients who fail medical management and elect endoscopic sinus ...
Mutreja, Isha Lan, Caixia Li, Qishun Aparicio, Conrado
Published in
Pharmaceutics
Dental implant-associated infection is a clinical challenge which poses a significant healthcare and socio-economic burden. To overcome this issue, developing antimicrobial surfaces, including antimicrobial peptide coatings, has gained great attention. Different physical and chemical routes have been used to obtain these biofunctional coatings, whi...
Ferraz-Amaro, Iván Corrales, Alfonso Atienza-Mateo, Belén Vegas-Revenga, Nuria Prieto-Peña, Diana Sánchez-Martín, Julio Almeida, Cristina Quevedo-Abeledo, Juan Carlos Blanco, Ricardo González-Gay, Miguel Á
...
Published in
Diagnostics (Basel, Switzerland)
Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD). Risk chart algorithms, such as the Systematic Coronary Risk Assessment (SCORE), often underestimate the risk of CVD in patients with RA. In this sense, the use of noninvasive tools, such as the carotid ultrasound, has made it possible to identify RA pati...
DiBlasi, Robert M Crandall, Coral N Engberg, Rebecca J Bijlani, Kunal Ledee, Dolena Kajimoto, Masaki Walther, Frans J
Published in
Pharmaceutics
Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor nebulizer efficiency and low pulmonary deposition. The study objective was to evaluate particle size, operational compatibility, and drug delivery efficiency with various nasal CPAP interfac...
Lin, Yaoyao Heidari, Ali Asghar Wang, Shuihua Chen, Huiling Zhang, Yudong
Published in
Biomimetics (Basel, Switzerland)
The Hunger Games Search (HGS) is an innovative optimizer that operates without relying on gradients and utilizes a population-based approach. It draws inspiration from the collaborative foraging activities observed in social animals in their natural habitats. However, despite its notable strengths, HGS is subject to limitations, including inadequat...
Bowker, Julie C Gurbacki, Jessica N Richard, Chloe L Rubin, Kenneth H
Published in
Behavioral sciences (Basel, Switzerland)
Anxious-withdrawal is a well-established individual risk factor for psychosocial difficulties during adolescence. It is unknown, however, whether it also places youth at increased risk for physical health problems, such as sleep difficulties. This study examines the concurrent and prospective associations between anxious-withdrawal and six types of...
Fleurence, Nolwenn Demeyer, Séverine Allard, Alexandre Douri, Sarah Hay, Bruno
Published in
Nanomaterials (Basel, Switzerland)
Thermal management is a key issue for the downsizing of electronic components in order to optimise their performance. These devices incorporate more and more nanostructured materials, such as thin films or nanowires, requiring measurement techniques suitable to characterise thermal properties at the nanoscale, such as Scanning Thermal Microscopy (S...
Lietuvninkas, Lina Baccouche, Basma Kazlauskas, Andrius
Published in
Biomedicines
The therapeutic benefit provided by anti-vascular endothelial growth factor (VEGF) for patients with vision-threatening conditions such as diabetic retinopathy (DR) demonstrates the important role of VEGF in this affliction. Cytokines, which can be elevated in the vitreous of patients with DR, promote leakage of retinal blood vessels, and may also ...
Kim, Jongkyu Lee, Namju Chun, Yoon-Seok Lee, Sang-Hoon Ku, Sae-Kwang
Published in
Marine drugs
Krill oil (KO) shows promise as a natural marine-derived ingredient for improving skin health. This study investigated its antioxidant, anti-inflammatory, anti-wrinkle, and moisturizing effects on skin cells and UVB-induced skin photoaging in hairless mice. In vitro assays on HDF, HaCaT, and B16/F10 cells, as well as in vivo experiments on 60 hairl...
