Ghadiri, Mohammad Mahdi Hosseini, Seied Ali Sadatsakkak, Seyed abbas Rajabpour, Ali
Published in
Biomedical Microdevices
Despite great developments in inertial microfluidics, there is still a lack of knowledge to precisely define the particles’ behavior in the microchannels. In the present study, as a prerequisite to experimental studies, numerical simulations have been used to study the capture efficiency of target particles in the contraction–expansion microchannel...
Duraiswamy, Suhanya Yung, Lin Yue Lanry
Published in
Biomedical Microdevices
We present an analysis of the microfluidic Dean migration of 2.5 µm particles, which do not meet focus criterion, in tall and low aspect ratio microchannels. We demonstrate the use of such low aspect ratio and tall spirals (h > 50 µm) for isolating high concentration (> 106 particles or cells/mL) micron sized particles without an initial off-chip d...
Liang, Dong-yu Liang, Peng-chen Yi, Qing-qing Sha, Shuang Shi, Jun-feng Chang, Qing
Published in
Biomedical Microdevices
Micro-arc oxidation (MAO) was used to improve the resistance of pure magnesium (Mg). Copper (Cu), a good antibacterial, angiogenic, and osteogenic element, was added by reaction in a Cu-containing electrolyte to improve the osteogenic and pro-angiogenic activities of Mg. The surface microstructures of the resulting MAO were evaluated by a scanning ...
Mizuno, Yuki Takasawa, Kanae Hanada, Taichi Nakamura, Kyou Yamada, Kazuya Tsubaki, Hirotada Hara, Masaya Tashiro, Yasunori Matsuo, Masaaki Ito, Takahiro
...
Published in
Biomedical Microdevices
In this study, we fabricated two different microneedles (MNs) — semi-hollow and bird-bill — to overcome the limitations of solid and coated MNs, respectively. The two MN arrays were developed using a general injection molding process to obtain high-quality MNs with uniform shape. The semi-hollow and bird-bill MNs could penetrate the micropores of s...
Abid, Zarmeena Andreoli, Francesca Kristensen, Maja N. Petersen, Ritika S. Müllertz, Anette Boisen, Anja Keller, Stephan S.
Published in
Biomedical Microdevices
Micro-reservoir based drug delivery systems have the potential to provide targeted drug release locally in the intestine, i.e. at the inflamed areas of the intestine of patients with inflammatory bowel disease (IBD). In this study, microcontainers with a diameter of 300 µm and a height of 100 µm, asymmetrical geometry and the possibility to provide...
Dhiman, Tarun Kumar Poddar, Mrinal Lakshmi, G. B. V. S. Kumar, Rahul Solanki, Pratima R.
Published in
Biomedical Microdevices
Glucose measurement is one of the essential health monitoring practices for maintaining blood sugar levels. Here, we have fabricated a highly specific capacitive nano-sensor for non-enzymatic glucose detection. Capacitance measurements were carried out on polyvinyl alcohol capped copper oxide (PVA-CuO) thin films on indium tin oxide (ITO) coated gl...
Farooq, Amina Butt, Nauman Zafar Hassan, Umer
Published in
Biomedical Microdevices
The impedimetric sensing techniques for single cell characterization have witnessed growing interest due to their high sensitivity and widespread applications. However, adapting the method to different biological measurements in microfluidic environments under various input conditions can result in feeble signal detection leading to a drastic decre...
Ebrahimi Fana, Saeed Paknejad, Maliheh Aminian, Mahdi
Published in
Biomedical Microdevices
The clinical importance of blood group (BG) antigens is related to their ability to induce immune antibodies that can cause hemolysis. Yet, ABO and D (Rh) are still considered to be the key antigens for healthy blood transfusion and secondary antigens are the next priority. Serological typing is the most widely used typing method. Rapid and accurat...
Rahman, Mohammad Rizwen Ur Kwak, Tae Joon Woehl, Jörg C. Chang, Woo-Jin
Published in
Biomedical Microdevices
Dielectrophoresis, an electrokinetic technique, can be used for contactless manipulation of micro- and nano-size particles suspended in a fluid. We present a 3-D microfluidic DEP device with an orthogonal electrode configuration that uses negative dielectrophoresis to trap spherical polystyrene micro-particles. Traps with three different basic geom...
Waghchaure, Mansi Govardhane, Sharayu Shende, Pravin
Published in
Biomedical Microdevices
The main objective of the present study was to prepare and evaluate dissolvable microneedle patch containing nanoparticles of tetanus toxoid without the use of any adjuvant and its immunopotentiation activity. Immunization with microneedles is a novel approach in vaccines delivery with advantages such as convenience, simple, and non-invasive therap...
