Galera, Cédric Barbosa, Susana Collet, Ophélie Khalfallah, Olfa Aouizerate, Bruno Sutter-Dalley, Anne-Laure Koehl, Muriel Capuron, Lucile Van der Waerden, Judith Melchior, Maria
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Published in
Biological psychiatry
Recent research suggests that immune dysregulation in pregnancy could be a risk factor for anxiety and depression symptoms in offspring. Whereas animal studies have demonstrated the importance of the link between perinatal cytokines and abnormal behaviors in offspring, human epidemiological studies in this area remain limited. The objectives of the...
Linke, Julia O Abend, Rany Kircanski, Katharina Clayton, Michal Stavish, Caitlin Benson, Brenda E Brotman, Melissa A Renaud, Olivier Smith, Stephen M Nichols, Thomas E
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Published in
Biological psychiatry
Imaging research has not yet delivered reliable psychiatric biomarkers. One challenge, particularly among youth, is high comorbidity. This challenge might be met through canonical correlation analysis designed to model mutual dependencies between symptom dimensions and neural measures. We mapped the multivariate associations that intrinsic function...
Polanska, Kinga Kaluzny, Pawel Aubert, Adrien M Bernard, Jonathan Y Duijts, Liesbeth El Marroun, Hanan Hanke, Wojciech Hébert, James R Heude, Barbara Jankowska, Agnieszka
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Published in
Biological psychiatry
The impact of maternal diet during pregnancy on child neurodevelopment is of public health and clinical relevance. We evaluated the associations of dietary quality based on the Dietary Approaches to Stop Hypertension (DASH) score and dietary inflammatory potential based on the energy-adjusted Dietary Inflammatory Index (E-DII) score during pregnanc...
Smeland, Olav B Shadrin, Alexey Bahrami, Shahram Broce, Iris Tesli, Martin Frei, Oleksandr Wirgenes, Katrine V O'Connell, Kevin S Krull, Florian Bettella, Francesco
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Published in
Biological psychiatry
Parkinson's disease (PD) and schizophrenia (SCZ) are heritable brain disorders that involve dysregulation of the dopaminergic system. Epidemiological studies have reported potential comorbidity between the disorders, and movement disturbances are common in patients with SCZ before treatment with antipsychotic drugs. Despite this, little is known ab...
Ambar Akkaoui, Marine Lejoyeux, Michel Geoffroy, Pierre A
Published in
Biological psychiatry
Chang, Hong Cai, Xin Li, Hui-Juan Liu, Wei-Peng Zhao, Li-Juan Zhang, Chu-Yi Wang, Jun-Yang Liu, Jie-Wei Ma, Xiao-Lei Wang, Lu
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Published in
Biological psychiatry
Genome-wide association studies (GWASs) have reported hundreds of genomic loci associated with schizophrenia, yet identifying the functional risk variations is a key step in elucidating the underlying mechanisms. We applied multiple bioinformatics and molecular approaches, including expression quantitative trait loci analyses, epigenome signature i...
Cisler, Josh M Herringa, Ryan J
Published in
Biological psychiatry
Posttraumatic stress disorder (PTSD) in adolescents is common and debilitating. In contrast to adult PTSD, relatively little is known about the neurobiology of adolescent PTSD, nor about how current treatments may alter adolescent neurodevelopment to allow recovery from PTSD. Improving our understanding of biological mechanisms of adolescent PTSD, ...
Andrews, Jack L Ahmed, Saz P Blakemore, Sarah-Jayne
Published in
Biological psychiatry
Successful navigation of the social environment is dependent on a number of social cognitive processes, including mentalizing and resistance to peer influence. These processes continue to develop during adolescence, a time of significant social change, and are underpinned by regions of the social brain that continue to mature structurally and funct...
Luna, Beatriz Tervo-Clemmens, Brenden Calabro, Finnegan J
Published in
Biological psychiatry
Martin, Joanna Khramtsova, Ekaterina A Goleva, Slavina B Blokland, Gabriëlla A M Traglia, Michela Walters, Raymond K Hübel, Christopher Coleman, Jonathan R I Breen, Gerome Børglum, Anders D
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Published in
Biological psychiatry
The origin of sex differences in prevalence and presentation of neuropsychiatric and behavioral traits is largely unknown. Given established genetic contributions and correlations, we tested for a sex-differentiated genetic architecture within and between traits. Using European ancestry genome-wide association summary statistics for 20 neuropsychia...
