Rate of re-positive RT-PCR test among patients recovered from COVID-19.
Published in Biochemia medica
SARS-CoV-2 - a new challenge for laboratory medicine.
Published in Biochemia medica
The new corona virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) causes a disease called COVID-19 (coronavirus disease 2019), that develops mostly in subjects with already impaired immune system function, primarily in the elderly and in individuals with some chronic disease or condition. The reasons for this should be sought in th...
Urine neutrophil gelatinase-associated lipocalin concentration in healthy newborns during the first three postnatal days...
Published in Biochemia Medica
Introduction Urine neutrophil gelatinase-associated lipocalin (uNGAL) is a biochemical marker significant for early prediction of acute kidney injury in adults. However, it has not been examined sufficiently among the infant population, particularly newborns in terms of reference values. The aim of our study was to determine the concentration of uN...
Comparison of a rapid immunochromatographic test with a chemiluminescence immunoassay for detection of anti-SARS-CoV-2 I...
Published in Biochemia Medica
Introduction The 2019 Coronavirus disease (COVID-19) has been characterized as a pandemic, representing a serious global public health emergency. Serological tests have been proposed as reliable tools for detecting Coronavirus SARS-CoV-2 antibodies in infected patients, especially for surveillance or epidemiological purposes. The aim of this study ...
Verification of automated latex-enhanced particle immunoturbidimetric D-Dimer assays on different analytical platforms a...
Published in Biochemia Medica
Introduction The aim of the study was the analytical verification of automated latex-enhanced particle immunoturbidimetric (LPIA) D-Dimer assay INNOVANCE D-dimer on Sysmex CS-5100 and Atellica COAG 360 analysers, and HemosIL D-dimer HS500 on ACL TOP 550, as well as the comparison with the enzyme-linked immunofluorescent assay (ELFA) on the miniVida...
Inflammatory and angiogenic biomarkers in diabetic retinopathy.
Published in Biochemia medica
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus (DM) and a leading cause of blindness in working-age adults in developed countries. Numerous investigations have recognised inflammation and angiogenesis as important factors in the development of this complication of diabetes. Current methods of DR...
A method comparison study of a point-of-care blood gas analyser with a laboratory auto-analyser for the determination of...
Published in Biochemia medica
Hyperkalaemia is a common electrolyte disorder that may cause life-threatening cardiac arrythmias. We aimed to determine the agreement of potassium concentrations between GEM premier 3500 point-of-care blood gas analyser (POC-BGA) and Roche Cobas 6000 c501 auto-analyser in patients with hyperkalaemia. A prospective, cross-sectional study of all con...
Potential of modern circulating cell-free DNA diagnostic tools for detection of specific tumour cells in clinical practi...
Published in Biochemia medica
Personalized medicine is a developing field of medicine that has gained in importance in recent decades. New diagnostic tests based on the analysis of circulating cell-free DNA (cfDNA) were developed as a tool of diagnosing different cancer types. By detecting the subpopulation of mutated DNA from cancer cells, it is possible to detect the presence...
Analysis of serum homocysteine in the laboratory practice - comparison of the direct chemiluminescence immunoassay and h...
Published in Biochemia medica
Effective diagnosis of cardiovascular diseases requires the right tools to be used enabling selective and sensitive analysis of their biomarkers. One of them is homocysteine (Hcy), nowadays determined by immunoassays and chromatographic methods. This study aims to compare the results obtained by direct chemiluminescence immunoassay (CLIA) and high ...
Test results comparison and sample stability study: is the BD Barricor tube a suitable replacement for the BD RST tube?
Published in Biochemia Medica
Introduction The aim was to evaluate the BD Barricor tubes by comparison with the BD Rapid Serum Tubes (RST) through measuring 25 analytes and monitoring sample stability after 24 hours and 7 days. Materials and methods Samples of 52 patients from different hospital departments were examined. Blood was collected in BD RST and BD Barricor tubes (Bec...
