Lv, Yunfeng He, Jingyun Liu, Rongzhi Gao, Yu Xu, Chao Hu, Peng Zheng, Shengwei Fang, Li Li, Ran Han, Congyin
...
Published in
Bioanalysis
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 antibody testing an important supplement to nucleic acid testing. In the process of emergency approval, the Center for Medical Device Evaluation of the China National Medical Products Administration released The Key Po...
Sen, Arundhuti Gilllett, Molly Weaver, Lucy Barfield, Matthew Singh, Pawanbir Lapierre, Florian Spooner, Neil
Published in
Bioanalysis
Background: The hemaPEN is a liquid microsampling device for the reproducible collection and storage of blood samples as dried blood spots, for subsequent quantitative analysis. Materials & methods: We examined the device's ability to collect accurate and precise blood volumes, at different hematocrit levels, via in vitro studies using acetaminophe...
Eangoor, Padmanabhan Das, Sharmistha Pucci, Vincenzo
Published in
Bioanalysis
Drug discovery is moving at a rapid pace and a fast turnaround of bioanalytical data is needed to sustain this pace. This article focuses on the evaluation of time-saving homogeneous proximity immunoassays such as Amplified Luminescent Proximity Homogeneous Assay, Time-Resolved Fluorescence Resonance Energy Transfer and Spatial Proximity Analyte Re...
Li, Hongran He, Jingyun Bao, Wen Wang, Peirong Lv, Yunfeng Xu, Chao Hu, Peng Gao, Yu Zheng, Shengwei An, Juanjuan
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Published in
Bioanalysis
Coronavirus disease-2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally since its first report and become a worldwide pandemic. In response to the outbreak of COVID-19, Center for Medical Device Evaluation, NMPA (CMDE) initiated emergency review and approval procedures to accelerate...
Sun, Yuchen Nitta, Shin-Ichiro Saito, Kosuke Hosogai, Ryuta Nakai, Keiko Goda, Ryoya Kakehi, Masaaki Murata, Kazuyuki Yamaguchi, Takeru Okuzono, Takeshi
...
Published in
Bioanalysis
Background: Ion-pairing reverse-phase LC coupled with high-resolution mass spectrometry (IP-LC/HRMS) has gained attention in oligonucleotide therapeutic bioanalyses owing to its high sensitivity and selectivity. However, optimization and validation of IP-LC/HRMS-based methods are rare. The objective of this study is the development of a sensitive a...
Zava, Theodore T Zava, David T
Published in
Bioanalysis
Aim: Coronavirus disease 2019 antibody testing often relies on venous blood collection, which is labor-intensive, inconvenient and expensive compared with finger-stick capillary dried blood spot (DBS) collection. The purpose of our work was to determine if two commercially available anti-severe acute respiratory syndrome coronavirus 2 enzyme-linked...
Heinig, Katja Zwanziger, Elke Potter, Julian Fraier, Daniela
Published in
Bioanalysis
Wang, Weiping Li, Pengyan Fang, Mengna Li, Xiaoting Zhang, Yu Zhang, Tianhong
Published in
Bioanalysis
Aim: Nimodipine and 3-n-butylphthalide are co-administered to treat vascular dementia, but the pharmacokinetic interaction between the two drugs is still unknown. Therefore, a robust, high-throughput and economical supercritical fluid chromatography-ESI-MS/MS method has been initially developed to simultaneously determine nimodipine and 3-n-butylph...
Simão, Ana Y Antunes, Mónica Marques, Hernâni Rosado, Tiago Soares, Sofia Gonçalves, Joana Barroso, Mário Andraus, Maristela Gallardo, Eugenia
Published in
Bioanalysis
One of the problems associated with the consumption of new psychoactive substances is that in most scenarios of acute toxicity the possibility of quick clinical action may be impaired because many screening methods are not responsive to them, and laboratories are not able to keep pace with the appearance of new substances. For these reasons, develo...
Ramos Santos, Wilson José Jr De Martinis, Bruno Spinosa
Published in
Bioanalysis
WHO recommends breastfeeding for the first 6 months of newborn's life. Due to its physicochemical properties, breast milk may contain undesirable components originated from mother's feeding, medication and illicit drugs consumption. Some of these substances transferred from bloodstream to milk and delivered to the infant can cause harmful effects. ...
