Mumtaz, Muhammad Zahid Kausar, Fareeda Hassan, Mubashir Javaid, Shaista Malik, Arif
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundMoringa oleifera is a common vegetable in many countries since ancient times, possesses numerous phenolic compounds having a wide array of biological activities. It possesses anticancer activity that can be used to develop new drugs for treatment of various types of cancers. The current study was conducted to evaluate the composition of p...
Omotoso, Olabode E. Babalola, Ayoade D. Matareek, Amira
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundSince outbreak in December 2019, the highly infectious and pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over a million deaths globally. With increasing burden, the novel coronavirus has posed a dire threat to public health, social interaction, and global economy. Mutations in the SARS-CoV-2 genome are...
AbdelMassih, Antoine Fakhry Ashraf, Ahmed Ismail, Habiba-Allah AbdelAzeim, Bassant Barsoum, Ihab Hany Girgis, Shady Afdal, George AbdelAzeim, Nesrine Afdal, Peter Menshawey, Esraa
...
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundPioglitazone’s role in the induction of atheroma regression in diabetics was suggested by several RCT. The aim of our study was to evaluate this role through a systematic review of all RCT conducted on this subject.MethodsLiterature was searched for relevant studies. We included all RCT that compared pioglitazone versus other antidiabetic...
Kothandan, Ram Rajan, Cashlin Anna Suveetha Gnana Arjun, Janamitra Raj, Rejoe Raymond Michael Syed, Sowfia
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundThe present pandemic situation due to coronavirus has led to the search for newer prevention, diagnostic, and treatment methods. The onset of the corona infection in a human results in acute respiratory illness followed by death if not diagnosed and treated with suitable antiretroviral drugs. With the unavailability of the targeted drug t...
Dwivedi, Manish Kumar Mishra, Shringika Sonter, Shruti Singh, Prashant Kumar
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundThe objectives of the current study are to evaluate the traditionally used medicinal plants Andrographis paniculata for in vitro anti-malarial activity against human malarial parasite Plasmodium falciparum and to further characterize the anti-malarial active extract of A. paniculata using spectroscopic and chromatographic methods.ResultsT...
Sebak, Mohamed Saafan, Amal E. Abdelghani, Sameh Bakeer, Walid Moawad, Abeer S. El-Gendy, Ahmed O.
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundThe rapid spread of antibiotic resistance has increased research interest in the discovery of natural products, mainly from actinomycetes, which have been the primary source of antimicrobial compounds. This study aimed to isolate, characterize, and optimize the production of some of the bioactive compounds from bioactive soil actinomycete...
Kalariya, Kuldeepsingh A. Meena, Ram Prasnna Poojara, Lipi Shahi, Deepa Patel, Sandip
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundSqualene synthase (SQS) is a rate-limiting enzyme necessary to produce pentacyclic triterpenes in plants. It is an important enzyme producing squalene molecules required to run steroidal and triterpenoid biosynthesis pathways working in competitive inhibition mode. Reports are available on information pertaining to SQS gene in several pla...
Chikopela, Theresa Heimburger, Douglas C. Kaluba, Longa Hamambulu, Pharaoh Simfukwe, Newton Mutale, Wilbroad Koethe, John R. Goma, Fastone
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundEndothelial function is dependent on the balance between vasoconstrictive and vasodilatory substances. The endothelium ability to produce nitric oxide is one of the most crucial mechanisms in regulating vascular tone. An increase in inducible nitric oxide synthase contributes to endothelial dysfunction in overweight persons, while oxidati...
Azmi, Sarfuddin Hussain, Mohd Kamil
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundAntimicrobial peptides are very primitive innate defense molecules of almost all organisms, from microbes to mammalians and vascular seed-bearing plants. Antimicrobial peptides of plants categorized into cysteine-rich peptides (CRPs) and others and most of the antimicrobial peptides belong to CRPs group. These peptides reported showing th...
Mohamed, Mohamed A. Awad, Hassan M.
Published in
Beni-Suef University Journal of Basic and Applied Sciences
BackgroundBioprospecting lipase producers in non-conventional habitats are the way to find special enzymes of diverse applications. Halo-alkaline marshes in Wadi El Natrun in Egypt are some of the most stable ecological systems in the world, and because of the double extremities of alkalinity and salinity, they harbor individual microbes capable of...