Published in BMJ Open
Objectives To estimate age-specific and sex-specific mortality risk among all SARS-CoV-2 infections in four settings in India, a major lower-middle-income country and to compare age trends in mortality with similar estimates in high-income countries. Design Cross-sectional study. Setting India, multiple regions representing combined population >150...
Published in BMJ open
This study explores the hospital journey of patients with intellectual disabilities (IDs) compared with the general population after admission for COVID-19 during the first wave of the pandemic (when demand on inpatient resources was high) to identify disparities in treatment and outcomes. Matched cohort study; an ID cohort of 506 patients were mat...
Published in BMJ open
To analyse preferences around promotion of COVID-19 vaccination among workers in the healthcare and welfare sector in Fance at the start of the vaccination campaign. Single-profile discrete-choice experiment. Respondents in three random blocks chose between accepting or rejecting eight hypothetical COVID-19 vaccination scenarios. 4346 healthcare an...
Published in BMJ open
Early in the COVID-19 pandemic, US Veterans Health Administration (VHA) employee occupational health (EOH) providers were tasked with assuming a central role in coordinating employee COVID-19 screening and clearance for duty, representing entirely novel EOH responsibilities. In a rapid qualitative needs assessment, we aimed to identify learnings fr...
Published in BMJ open
To evaluate the spatiotemporal distribution of the incidence of COVID-19 hospitalisations in Birmingham, UK during the first wave of the pandemic to support the design of public health disease control policies. A geospatial statistical model was estimated as part of a real-time disease surveillance system to predict local daily incidence of COVID-1...
Published in BMJ open
Large data on the clinical characteristics and outcome of COVID-19 in the Indian population are scarce. We analysed the factors associated with mortality in a cohort of moderately and severely ill patients with COVID-19 enrolled in a randomised trial on convalescent plasma. Secondary analysis of data from a Phase II, Open Label, Randomized Controll...
Published in BMJ open
During the first COVID-19 wave in Switzerland, relative mortality was at least eight times higher compared with the uninfected general population. We aimed to assess sex-specific and age-specific relative mortality associated with a SARS-CoV-2 diagnosis during the second wave. Prospective population-based study. Individuals testing positive for SAR...
Published in BMJ Open
Objectives As early prediction of severe illness and death for patients with coronavirus disease 2019 (COVID-19) is important, we aim to explore the clinical value of laboratory indicators in evaluating the progression and prognosis of patients with COVID-19. Design Retrospective cohort study. Setting Hospital-based study in China. Participants Adu...
Published in BMJ Open
Objectives The COVID-19 pandemic instigated multiple societal and healthcare interventions with potential to affect perinatal practice. We evaluated population-level changes in preterm and full-term admissions to neonatal units, care processes and outcomes. Design Observational cohort study using the UK National Neonatal Research Database. Setting ...
Published in BMJ Open
Objectives To identify factors associated with COVID-19 test positivity and assess viral and antibody test concordance. Design Observational retrospective cohort study. Setting Optum de-identified electronic health records including over 700 hospitals and 7000 clinics in the USA. Participants There were 891 754 patients who had a COVID-19 test iden...
