Scott, Ian C. Mount, Julie Barry, Jane Kirkham, Bruce
Published in
BMC Rheumatology
Background Many patients with rheumatoid arthritis (RA) do not attain remission/low disease activity, remaining in a moderate disease activity state (MDAS) with ongoing disability and impaired quality of life (QoL). If patients in persistent MDAS with poor future outcomes could be prospectively identified, they could arguably be treated more intens...
Kumar, Kanta Arya, Suvrat Nightingale, Peter Sheeran, Tom Aggarwal, Amita
Published in
BMC Rheumatology
Background South Asians have a higher risk of cardiovascular disease (CVD). Rheumatoid arthritis (RA) increases the risk of premature atherosclerosis. We investigated whether there was a substantial difference in the level of CVD risk knowledge among patients of South Asian origin with RA in India and in the UK. Methods In this cross-sectional surv...
Razmjou, Amir A. Brook, Jenny Elashoff, David Kaeley, Gurjit Choi, Soo Kermani, Tanaz Ranganath, Veena K.
Published in
BMC Rheumatology
BackgroundMusculoskeletal ultrasound (MSUS) and the multi-biomarker disease activity (MBDA) score are outcome measures that may aid in the management of rheumatoid arthritis (RA) patients. This study evaluated tofacitinib response by MSUS/MBDA scores and assessed whether baseline MSUS/MBDA scores or their early changes predict later clinical respon...
Patel, Veena Stewart, Diana Horstman, Molly J.
Published in
BMC Rheumatology
BackgroundTo evaluate the effect of E-consults on wait times and resource utilization for positive antinuclear antibody (ANA) referrals in outpatient rheumatology.MethodsWe conducted a pre-post study of E-consult implementation for positive ANA referrals. We retrospectively reviewed “positive ANA” referrals from 1/2015–3/2017. A statistical process...
Bremander, Ann Malm, Karina Andersson, Maria L.
Published in
BMC Rheumatology
BackgroundA large number of patients with RA do not adhere to the recommended levels of physical activity to enhance health. According to EULAR recommendations, physical activity should be part of standard care in people with rheumatic diseases. There have been few larger studies on maintenance of physical activity over longer periods of time. The ...
Tawalbeh, Shefa M. Marin, Wilfredo Morgan, Gabrielle A. Dang, Utkarsh J. Hathout, Yetrib Pachman, Lauren M.
Published in
BMC Rheumatology
BackgroundBlood accessible biomarkers to assess disease activity and their response to therapies in Juvenile Dermatomyositis (JDM) are urgently needed. This pilot study aims to identify serum protein biomarkers associated with clinical disease activity in untreated JDM and their response to medical therapy.MethodsSomaScan® technology screened JDM p...
Masoumi, Maryam Tabaraii, Reihane Shakiba, Saeed Shakeri, Mansoureh Smiley, Abbas
Published in
BMC Rheumatology
BackgroundAssessment of the association of various lifestyle factors and wellness and health status in patients with Behcet’s disease was the main goal of this study.MethodsDemographic information, body mass index, smoking habit, mood status, sleep quality, physical activity levels, nutritional data, symptoms, signs, laboratory findings and patient...
Di Bartolomeo, Salvatore Carubbi, Francesco Cipriani, Paola
Published in
BMC Rheumatology
BackgroundHepatitis E virus (HEV) represents the most common cause of acute hepatitis and jaundice in the world. About 2 million of infection cases occur each year in Europe, mainly as autochthonous anthropozoonosis, and HEV can be transmitted through undercooked pork meat. This infection has been linked to various extra-hepatic manifestations, whi...
Oldroyd, Alexander Dixon, William Chinoy, Hector Howells, Kelly
Published in
BMC Rheumatology
BackgroundThe idiopathic inflammatory myopathies (IIMs) are chronic autoimmune conditions, typically resulting in proximal muscle weakness and impacting upon quality of life. Accurate measurement of IIM disease activity is imperative for appropriate medical management and carrying out valid clinical trials. The International Myositis Assessment and...
Rahman, Proton Baer, Philip Keystone, Ed Choquette, Denis Thorne, Carter Haraoui, Boulos Chow, Andrew Faraawi, Rafat Olszynski, Wojciech Kelsall, John
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Published in
BMC Rheumatology
BackgroundLong-term clinical registries are essential tools to evaluate new therapies in a patient population that differs from those in randomized clinical trials. The objectives are to describe the profile of rheumatoid arthritis (RA) patients treated with anti-TNF agents in Canadian routine care.MethodsRA patients eligible for treatment with Inf...
