Saito, Makoto Carrara, Verena I. Gilder, Mary Ellen Min, Aung Myat Tun, Nay Win Pimanpanarak, Mupawjay Viladpai-nguen, Jacher Paw, Moo Kho Haohankhunnatham, Warat Konghahong, Kamonchanok
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Published in
BMC Medicine
BackgroundArtemisinin and artemisinin-based combination therapy (ACT) partner drug resistance in Plasmodium falciparum have spread across the Greater Mekong Subregion compromising antimalarial treatment. The current 3-day artemether-lumefantrine regimen has been associated with high treatment failure rates in pregnant women. Although ACTs are recom...
Hiwasa, Takaki Wang, Hao Goto, Ken-ichiro Mine, Seiichiro Machida, Toshio Kobayashi, Eiichi Yoshida, Yoichi Adachi, Akihiko Matsutani, Tomoo Sata, Mizuki
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Published in
BMC Medicine
BackgroundAcute ischemic stroke (AIS) is a serious cause of mortality and disability. AIS is a serious cause of mortality and disability. Early diagnosis of atherosclerosis, which is the major cause of AIS, allows therapeutic intervention before the onset, leading to prevention of AIS.MethodsSerological identification by cDNA expression cDNA librar...
Jones, Christine Elizabeth Calvert, Anna Southern, Jo Matheson, Mary Andrews, Nick Khalil, Asma Cuthbertson, Hannah Hallis, Bassam England, Anna Heath, Paul T.
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Published in
BMC Medicine
BackgroundPertussis vaccines containing three or five pertussis antigens are recommended in pregnancy in many countries, but no studies have compared the effect on infants’ antigen-specific immunoglobulin G (IgG) concentrations. The aim of this study was to compare anti-pertussis IgG responses following primary immunization in infants of mothers va...
Southall, Emma Holmes, Alex Hill, Edward M. Atkins, Benjamin D. Leng, Trystan Thompson, Robin N. Dyson, Louise Keeling, Matt J. Tildesley, Michael J.
Published in
BMC Medicine
BackgroundThe introduction of SARS-CoV-2, the virus that causes COVID-19 infection, in the UK in early 2020, resulted in the introduction of several control policies to reduce disease spread. As part of these restrictions, schools were closed to all pupils in March (except for vulnerable and key worker children), before re-opening to certain year g...
Obiero, Christina W. Mturi, Neema Mwarumba, Salim Ngari, Moses Newton, Charles R. van Hensbroek, Michaël Boele Berkley, James A.
Published in
BMC Medicine
BackgroundDiagnosing bacterial meningitis is essential to optimise the type and duration of antimicrobial therapy to limit mortality and sequelae. In sub-Saharan Africa, many public hospitals lack laboratory capacity, relying on clinical features to empirically treat or not treat meningitis. We investigated whether clinical features of bacterial me...
Vidal-Petiot, Emmanuelle Gault, Nathalie
Published in
BMC Medicine
Owens, Sarah A. Eisenlohr-Moul, Tory A.
Published in
BMC Medicine
Khunti, Kamlesh Griffin, Simon Brennan, Alan Dallosso, Helen Davies, Melanie J. Eborall, Helen C. Edwardson, Charlotte L. Gray, Laura J. Hardeman, Wendy Heathcote, Laura
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Published in
BMC Medicine
BackgroundPhysical activity is associated with a reduced risk of type 2 diabetes and cardiovascular disease but limited evidence exists for the sustained promotion of increased physical activity within diabetes prevention trials. The aim of the study was to investigate the long-term effectiveness of the Walking Away programme, an established group-...
Louise, Jennie Poprzeczny, Amanda J. Deussen, Andrea R. Vinter, Christina Tanvig, Mette Jensen, Dorte Moller Bogaerts, Annick Devlieger, Roland McAuliffe, Fionnuala M. Renault, Kristina M.
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Published in
BMC Medicine
BackgroundThe impact of maternal obesity extends beyond birth, being independently associated with an increased risk of child obesity. Current evidence demonstrates that women provided with a dietary intervention during pregnancy improve their dietary quality and have a modest reduction in gestational weight gain. However, the effect of this on lon...
Rasella, Davide Alves, Flávia Jôse Oliveira Rebouças, Poliana de Jesus, Gabriela Santos Barreto, Maurício L. Campello, Tereza Paixao, Enny S.
Published in
BMC Medicine
BackgroundReducing poverty and improving access to health care are two of the most effective actions to decrease maternal mortality, and conditional cash transfer (CCT) programmes act on both. The aim of this study was to evaluate the effects of one of the world’s largest CCT (the Brazilian Bolsa Familia Programme (BFP)) on maternal mortality durin...
