Roy, Jérôme Baranek, Elodie Marandel, Lucie
Published in
BMC Genomics
Since 20 years of research, free fatty acids receptors (FFARs) have received considerable attention in mammals. To date, four FFARs (FFAR1, FFAR2, FFAR3 and FFAR4) are especially studied owing to their physiological importance in various biological processes. This ubiquitist group of G protein-coupled receptors (GPCRs) are majors reports in the key...
Wei, Yu-Miao Li, Xiang Xu, Ming Abais, Justine M. Chen, Yang Riebling, Christopher R. Boini, Krishna M. Li, Pin-Lan Zhang, Yang
Published in
Cellular Physiology and Biochemistry
Background/Aims: In addition to their action of lowering blood cholesterol levels, statins modulate biological characteristics and functions of arterial myocytes such as viability, proliferation, apoptosis, survival and contraction. The present study tested whether simvastatin, as a prototype statin, enhances autophagy in coronary arterial myocytes...
Boutet, Isabelle Jollivet, Didier Shillito, Bruce Moraga, Dario Tanguy, Arnaud
Published in
BMC Genomics
BackgroundHydrothermal vents and cold seeps represent oases of life in the deep-sea environment, but are also characterized by challenging physical and chemical conditions. The effect of temperature fluctuations on vent organisms in their habitat has not been well explored, in particular at a molecular level, most gene expression studies being cond...
Titus-McQuillan, James E Nanni, Adalena V McIntyre, Lauren M Rogers, Rebekah L
Published in
BMC genomics
Genomic complexity is a growing field of evolution, with case studies for comparative evolutionary analyses in model and emerging non-model systems. Understanding complexity and the functional components of the genome is an untapped wealth of knowledge ripe for exploration. With the "remarkable lack of correspondence" between genome size and comple...
Stefan, Kurtis Barski, Artem
Published in
BMC genomics
Cis-regulatory elements (CRE) are critical for coordinating gene expression programs that dictate cell-specific differentiation and homeostasis. Recently developed self-transcribing active regulatory region sequencing (STARR-Seq) has allowed for genome-wide annotation of functional CREs. Despite this, STARR-Seq assays are only employed in cell line...
Banouh, Meriem Armisen, David Bouguennec, Annaig Huneau, Cécile Sow, Mamadou Dia Pont, Caroline Salse, Jérôme Civáň, Peter
Published in
BMC genomics
Bread wheat is a recent allohexaploid (genomic constitution AABBDD) that emerged through a hybridization between tetraploid Triticum turgidum (AABB) and diploid Aegilops tauschii (DD) less than 10,000 years ago. The hexaploidization can be re-created artificially, producing synthetic wheat that has been used to study immediate genomic responses to ...
Yu, Dongliang Wu, Yuqing Zhu, Leilei Wang, Yuying Sheng, Donglai Zhao, Xiaofeng Liang, Guoqing Gan, Lin
Published in
BMC Genomics
Background The long non-coding RNAs (lncRNAs) are critical regulators of diverse biological processes. Nevertheless, a global view of its expression and function in the mouse retina, a crucial model for neurogenesis study, still needs to be made available. Results Herein, by integrating the established gene models and the result from ab initio pred...
Zhao, Ruzhou Wang, Xiaobo Zhou, Xiang Jiang, Shuai Zhang, Lin Yu, Zhibin
Published in
BMC Genomics
With the rising demand for entry to extremely high altitudes (HAs), rapid adaptability to extremely hypoxic environments is a challenge that we need to explore. Fasting was used to evaluate acute hypoxia tolerance at HA and was proven to be an effective method for improving the survival rate at extreme HA. Our experiments also showed that fasting p...
Ma, Qiang Niu, Chenxu Wang, Chao Chen, Chunhua Li, Yan Wei, Min
Published in
BMC Genomics
Background Rootstocks can improve the chilling tolerance of grafted cucumbers, but their effectiveness varies. Rootstocks with strong de-blooming capacity may result in lower chilling tolerance of grafted cucumbers compared to those with weak de-blooming capacity, while also reducing the silicon absorption. However, it remains unclear whether this ...
Sobol, Morgan S. Hoshino, Tatsuhiko Delgado, Victor Futagami, Taiki Kadooka, Chihiro Inagaki, Fumio Kiel Reese, Brandi
Published in
BMC Genomics
Background Marine deep subsurface sediments were once thought to be devoid of eukaryotic life, but advances in molecular technology have unlocked the presence and activity of well-known closely related terrestrial and marine fungi. Commonly detected fungi in deep marine sediment environments includes Penicillium , Aspergillus , Cladosporium , Fusar...
