Li, Xiang Shahid, Muhammad Qasim Xia, Juan Lu, Zijun Fang, Na Wang, Lan Wu, Jinwen Chen, Zhixiong Liu, Xiangdong
Published in
BMC Genomics
The above results not only provide the small RNAs changes during four landmark stages of pollen and embryo sac development in autotetraploid rice but also have identified specifically expressed miRNAs, especially meiosis-related miRNAs, pollen-specific-24 nt-phasiRNAs and TEs-siRNAs in autotetraploid rice. Together, these findings provide a foundat...
Riccardo Baroncelli Daniel Buchvaldt Amby Antonio Zapparata Sabrina Sarrocco Giovanni Vannacci Gaétan Le Floch Richard J. Harrison Eric Holub Serenella A. Sukno Surapareddy Sreenivasaprasad
...
Published in
BMC Genomics
pires pacheco, maria
Published in
BMC Genomics
Background: The reconstruction of context-specific metabolic models from easily and reliably measurable features such as transcriptomics data will be increasingly important in research and medicine. Current reconstruction methods suffer from high computational effort and arbitrary threshold setting. Moreover, understanding the underlying epigenetic...
Zhou, Shiguo Wei, Fusheng Nguyen, John Bechner, Mike Potamousis, Konstantinos Goldstein, Steve Pape, Louise Mehan, Michael R Churas, Chris Pasternak, Shiran
...
Published in
PLoS genetics
About 85% of the maize genome consists of highly repetitive sequences that are interspersed by low-copy, gene-coding sequences. The maize community has dealt with this genomic complexity by the construction of an integrated genetic and physical map (iMap), but this resource alone was not sufficient for ensuring the quality of the current sequence b...
Halper-Stromberg, Eitan Steranka, Jared Giraldo-Castillo, Nicolas Fuller, Timothy Desiderio, Stephen Burns, Kathleen H
Published in
BMC genomics
Our results demonstrate the ability of next generation sequencing to describe human V(D)J recombinase activity and provide a scalable means to chronicle off-target, unexpressed, and non-amplifiable recombinations occurring in the development of lymphoid cancers.
Smagulova, Fatima Brick, Kevin Pu, Yongmei Sengupta, Uttara Camerini-Otero, R Daniel Petukhova, Galina V
Published in
BMC genomics
Our data suggest that specific, yet-unidentified factors influence the initiation of meiotic recombination at subtelomeric chromosomal regions.
Kowalczuk, Maria K Nanda, Shreeya Moylan, Elizabeth C
Published in
BMC genomics
After publication of this article (Fernandez et al., BMC Genomics 2011, 12:604) it was brought to the Editors' attention that the data generated by the first author, Ariel Fernandez, seemed anomalous. One of the author's institutions found that the data were not reproducible from the described methods, but an investigation by the author's other ins...
Bell, Oliver Conrad, Thomas Kind, Jop Wirbelauer, Christiane Akhtar, Asifa Schübeler, Dirk
Published in
Molecular and cellular biology
In Drosophila melanogaster, dosage compensation relies on the targeting of the male-specific lethal (MSL) complex to hundreds of sites along the male X chromosome. Transcription-coupled methylation of histone H3 lysine 36 is enriched toward the 3' end of active genes, similar to the MSL proteins. Here, we have studied the link between histone H3 me...
Published in
BMC Genomics
Background Histone acetylation has been implicated in learning and memory in the brain, however, its function at the level of the genome and at individual genetic loci remains poorly investigated. This study examines a key acetylation mark, histone H4 lysine 5 acetylation (H4K5ac), genome-wide and its role in activity-dependent gene transcription i...
Published in
BMC Genomics
Background As the error rate is high and the distribution of errors across sites is non-uniform in next generation sequencing (NGS) data, it has been a challenge to estimate DNA polymorphism (θ) accurately from NGS data. Results By computer simulations, we compare the two methods of data acquisition - sequencing each diploid individual separately a...
