Chen, Jiang Li, Hongyu Xu, Wenda Guo, Xiaozhong
Published in
BMC Gastroenterology
BackgroundPancreatic cancer (PC) is a devastating disease that has a poor prognosis and a total 5-year survival rate of around 5%. The poor prognosis of PC is due in part to a lack of suitable biomarkers that can allow early diagnosis. The lysophospholipase autotaxin (ATX) and its product lysophosphatidic acid (LPA) play an essential role in diseas...
Hizuka, Keinosuke Hagiwara, Shin-ichiro Maeyama, Takatoshi Honma, Hitoshi Kawai, Masanobu Akagi, Kiwamu Yasuhara, Michiko Tomita, Naohiro Etani, Yuri
Published in
BMC Gastroenterology
BackgroundConstitutional mismatch repair deficiency (CMMRD) is caused by biallelic pathogenic variants in one of the mismatch repair genes, and results in early onset colorectal cancer, leukemia, brain tumors and other childhood malignancies. Here we report a case of CMMRD with compound heterozygous variants in the MSH6 gene, including a de novo va...
Wu, Lei-Lei Ma, Qi-Long Huang, Wei Liu, Xuan Qiu, Li-Hong Lin, Peng Long, Hao Zhang, Lan-Jun Ma, Guo-Wei
Published in
BMC Gastroenterology
BackgroundTo explore the postoperative prognosis of esophageal squamous cell carcinoma (ESCC) patients with stage IB/IIA, using a prognostic score (PS).MethodsStage IB/IIA ESCC patients who underwent esophagectomy from 1999 to 2010 were included. We retrospectively recruited 153 patients and extracted their medical records. Moreover, we analyzed th...
Xie, Tong-Hui Su, Peng Hong, Jian-Guo Zhang, Hui
Published in
BMC Gastroenterology
BackgroundColorectal cancer is a very common malignant tumor worldwide. The clinical manifestations of advanced colorectal cancer include the changes in bowel habits, hematochezia, diarrhea, local abdominal pain and other symptoms. However, the colorectal cancer with an initial symptom of cervical lymph node enlargement is extremely rare. In this a...
Flores, Virginia Martínez-Lozano, Helena Bighelli, Federico Orcajo, Javier García-Lledó, Javier Alonso-Farto, Juan Carlos Menchén, Luis
Published in
BMC Gastroenterology
BackgroundBile acid malabsorption occurs in up to one third of patients with chronic diarrhoea of functional characteristics. The gold standard test for its diagnosis is the 75Selenium homocholic acid taurine (75SeHCAT) test. The aim of this work is to confirm previous data suggesting that bile acid malabsorption, diagnosed by 75Se-HCAT test, is th...
Osawa, Yosuke Yoshio, Sachiyo Aoki, Yoshihiko Korenaga, Masaaki Imamura, Masatoshi Oide, Takashi Okawara, Miku Kawai, Hironari Tsutsui, Yuriko Yoshida, Yuichi
...
Published in
BMC Gastroenterology
BackgroundPathological angiogenesis is involved in the development of hepatocellular carcinoma. In patients with chronic hepatitis C (CHC), the level of angiogenic factor angiopoietin (ANGP)-2 is reported to be increased in the blood, correlating with fibrosis. In this study, we aimed to clarify whether blood ANGP-2 is useful as a biomarker for liv...
Xu, Fenghua Li, Ning Wang, Chun Xing, Hanyang Chen, Dongfeng Wei, Yanling
Published in
BMC Gastroenterology
BackgroundSmall intestinal bacterial overgrowth (SIBO) is characterized by the condition that bacteria overgrowth in the small intestine. Fecal microbiota transplantation (FMT) has been applied as an effective tool for reestablishing the structure of gut microbiota. However, whether FMT could be applied as a routine SIBO treatment has not been inve...
Ledergerber, Martina Lang, Brian M. Heinrich, Henriette Biedermann, Luc Begré, Stefan Zeitz, Jonas Krupka, Niklas Rickenbacher, Andreas Turina, Matthias Greuter, Thomas
...
Published in
BMC Gastroenterology
BackgroundAbdominal pain is a frequent symptom in patients with inflammatory bowel disease (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC). Pain can result from ongoing inflammation or functional disorders imitating irritable bowel syndrome (IBS). Several single-nucleotide polymorphisms (SNPs) have been associated with IBS. However...
Liu, Chang Yang, Fang Zhang, Wenming Ao, Weiqun An, Yongyu Zhang, Cui Dai, Bailing Pu, Cailing Wang, Jian
Published in
BMC Gastroenterology
BackgroundGastric ectopic pancreas (GEPs) is a rare developmental anomaly which is difficult to differentiate it from submucosal tumor such as gastric stromal tumor (GST) by imaging methods. Since the treatments of the GEPs and GST are totally different, a correct diagnosis is essential. Therefore, we retrospectively investigated the CT features of...
Lucatelli, Pierleone De Rubeis, Gianluca Rocco, Bianca Basilico, Fabrizio Cannavale, Alessandro Abbatecola, Aurelio Nardis, Pier Giorgio Corona, Mario Brozetti, Stefania Catalano, Carlo
...
Published in
BMC Gastroenterology
BackgroundTo compare oncological results and safety profile of balloon micro-catheter trans-arterial chemoembolization (b-TACE) and drug-eluting-microsphere (DEM-TACE) in patients with hepatocellular-carcinoma (HCC).MethodsThis is a case–control, retrospective, single-center study. Between January-2015/March-2019, 149 patients (131 males [87.9%]) w...