Pingali, Usharani Nutalapati, Chandrasekhar Koilagundla, Niranjan Taduri, Gangadhar
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BMC Complementary Medicine and Therapies
BackgroundHyperuricemia is an independent risk factor in chronic kidney disease (CKD). Allopurinol and febuxostat are prescription medicines used to treat hyperuricemia but suffer side-effects. Earlier clinical study has shown that an aqueous extract of Terminalia bellerica (TBE), significantly reduced uric acid levels with no serious adverse effec...
Zhang, Changrong Huang, Yongquan Li, Peiwu Chen, Xinlin Liu, Fengbin Hou, Qiuke
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BMC Complementary Medicine and Therapies
BackgroundGinger or ginger extracts have been used in traditional medicine relieve pain caused by diarrhea predominant irritable bowel syndrome (IBS-D), but few data exists about its effectiveness. This present study was to validate the effect of ginger on visceral pain, and to further explore the possible underlying mechanism by which ginger is us...
Xu, Min Hu, Tian-Yong Li, Dong-Cai Ma, Li Zhang, Hua Fan, Jun-Ting Fan, Xiao-Mei Zeng, Xian-Hai Qiu, Shu-Qi Liu, Zhi-Qiang
...
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BMC Complementary Medicine and Therapies
BackgroundYan Hou Qing (YHQ) is a Chinese medicinal formula designed to alleviate sore throat symptoms, but underlying mechanism of YHQ treatment for pharyngitis is poorly defined up to now.MethodsIn this study, the modulation of YHQ on pharyngitis is investigated in ammonia-induced acute pharyngitis rat models. After treatment with YHQ or dexameth...
Matowa, Patrick Rutendo Gundidza, Mazuru Gwanzura, Lovemore Nhachi, Charles F. B.
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BMC Complementary Medicine and Therapies
BackgroundTraditional medicine plays an important role in health care provision in the developing world. A number of cancer patients have been found to be using traditional medicine as primary therapy and/or as complementary medicine. Cancer is one of the leading causes of morbidity and mortality globally among the non-communicable diseases. The ai...
Mvondo, Marie Alfrede Mzemdem Tsoplfack, Flavie Ingrid Awounfack, Charline Florence Njamen, Dieudonné
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BMC Complementary Medicine and Therapies
BackgroundMyrianthus arboreus P. Beauv. (Cecropiaceae) is a medicinal plant used to treat female infertility. The aqueous extract of M. arboreus leaves was found to improve the fertility of healthy female Wistar rats. In the present study, we proposed evaluating the effects of such an extract on an animal model of infertility caused by polycystic o...
Siddiqui, Sahabjada Mahdi, Abbas Ali Arshad, Md
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BMC Complementary Medicine and Therapies
BackgroundThe present study was designed to examine the role of isoflavone genistein (GS) on bone formation, regulating oxidative stress and cell cycle in primary osteoblasts, as well as attenuation of osteoclast formation.MethodsPrimary calvaria osteoblasts were isolated from 2 to 3 days old neonatal rat pups (n = 6–8) of Sprague Dawley rats. Oste...
Li, Yanyan Li, Yunyi Fang, Zhie Huang, Dan Yang, Yalin Zhao, Dijia Hang, Mingchun Wang, Junda
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BMC Complementary Medicine and Therapies
BackgroundIn this study, Malus doumeri leaf flavonoids (MDLF) were used as the research object to observe their in vitro antioxidant stress ability. Hydrogen peroxide (H2O2) was used to induce oxidative stress in 293 T cells.MethodsMTT, flow cytometry, and qPCR were used to verify the effect of MDLF.ResultsIn vitro cell experiments showed that at a...
Shi, Peiying Geng, Qianqian Chen, Lifu Du, Tianyu Lin, Yan Lai, Rongcai Meng, Fei Wu, Zhenhong Miao, Xiaoqing Yao, Hong
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BMC Complementary Medicine and Therapies
BackgroundSchisandra chinensis (Turcz.) Baill bee pollen extract (SCBPE) is often used as a functional food in China due to its good antioxidant property. However, its chemical compositions and effects on H9c2 cardiomyocytes against H2O2-induced cell injury still lacks of reports thus far. This study aimed to characterize the main components of SCB...
Mutuku, Angela Mwamburi, Lizzy Keter, Lucia Ondicho, Joyce Korir, Richard Kuria, James Chemweno, Timothy Mwitari, Peter
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BMC Complementary Medicine and Therapies
BackgroundMedicinal plants have been used in the treatment of various ailments in most developing countries. Oral infections are the most prevalent diseases in man. The Rhus family has been found to have antimicrobial, antimalarial, and anti-inflammatory properties. Few studies have been done on Rhus vulgaris Meikle. A study was conducted to determ...
Nayim, Paul Mbaveng, Armelle T. Ntyam, Arsene M. Kuete, Victor
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BMC Complementary Medicine and Therapies
BackgroundThe cytotoxicity of the root’s methanol extract of Imperata cylindrica (ICR). was previously reported in a panel of human cancer cell lines, including multi-drug resistant phenotypes. The aim of this study was to assess the acute and sub-chronic oral toxicity of methanol root extract of Imperata cylindrica.MethodsThe acute toxicity was ca...
