Sarto, Marcella Paula Mansano Lucas da Silva, Hevillyn Fernanda de Souza Fernandes, Nilma de Abreu, Ana Paula Zanusso Junior, Gerson de Ornelas Toledo, Max Jean
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BMC Complementary Medicine and Therapies
Background Trypanosoma cruzi is the etiological agent of Chagas disease (CD) or American trypanosomiasis, an important public health problem in Latin America. Benznidazole (BZ), a drug available for its treatment, has limited efficacy and significant side effects. Essential oils (EOs) have demonstrated trypanocidal activity and may constitute a the...
Li, Yuqin Lu, Xiaolan Tian, Peiying Wang, Kai Shi, Jianping
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BMC Complementary Medicine and Therapies
Background Procyanidin B2 (PB2), a unique component of the grape seed and other medicinal plants. PB2 has shown wide anticancer activity in various human cancer cells. However, it remains unclear about the biological effects and associated mechanisms of PB2 on gastric cancer cells. Methods Cell proliferation was measured by CCK8 assay, and cellular...
El Charif, Mohamad Hadi Doughan, Samer Kredly, Rawya Kassas, Sara Azab, Rayan Sbaity, Eman
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BMC Complementary Medicine and Therapies
Background Anal fissure is a common complication of the anorectal region and one of the most reported causes of anal pain. Acute anal fissure can be cured by surgery or medical treatment. There is an increase in the use of topical therapy for the treatment of anal fissures. A common topical drug used is Diltiazem (DTZ), a calcium-channel blocker, w...
Gadisa, Eshetu Tadesse, Elazar
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BMC Complementary Medicine and Therapies
Background Medicinal plants have wide medicament application used to prevent and management of many ailments. These plants are used for primary health care in pastoralist communities who are deprived of modern medical care. They possess extensive therapeutics bioactive coupled with varied chemical structures. However, scientific validation of effic...
Nazir, Nausheen Zahoor, Muhammad Uddin, Faheem Nisar, Mohammad
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BMC Complementary Medicine and Therapies
Background Elaeagnus umbellata Thunb. (autumn olive) is a high valued medicinal plant. It belongs to Elaeagnaceae family and is widely distributed in Himalayan regions of Pakistan. In the present study essential oil were extracted from the fruit of this plant and their antioxidant, anticholinesterase and antidiabetic potentials were also evaluated....
Zhang, Xiaoxiao Shao, Changle Cheng, Songyi Zhu, Yao Liang, Bo Gu, Ning
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BMC Complementary Medicine and Therapies
Background Acute myocardial infarction (AMI) is the most serious and lethal manifestation of coronary heart disease worldwide, presenting extremely high disability and mortality. Our previous studies have shown that Guanxin V (GXV) could significantly improve the cardiac function and the blood flow dynamics, and reduce serum levels of inflammatory ...
Wu, Chengjie Yang, Guanglu Pan, Yalan Wang, Lei Tu, Pengcheng Zheng, Suyang Guo, Yang Ma, Yong
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BMC Complementary Medicine and Therapies
Background Endoplasmic reticulum stress (ERS) is one of the main mechanisms of spinal cord injury (SCI) pathology and can affect the physiological state of neurons. Icariin (ICA), the main pharmacological component of Epimedium, can relieve the symptoms of patients with SCI and has obvious protective effects on neurons through ERS. Methods PC12 cel...
Ekasari, Wiwied Basuki, Dewi Resty Arwati, Heny Wahyuni, Tutik Sri
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BMC Complementary Medicine and Therapies
Background In previous studies, Cassia spectabilis DC leaf has shown a good antiplasmodial activity. Therefore, this study is a follow-up study of the extract of leaf of C. spectabilis DC on its in vitro and in vivo antiplasmodial activity and mechanism as an antimalarial. Methods The extract was fractionated, sub-fractionated and isolated to obtai...
Tesfamariam, Sirak Tesfai, Filmon Hussien, Lemlem Ateshim, Yonatan Yemane, Dawit Russom, Mulugeta Ahmed, Hagos Bahta, Iyassu Kidane, Solyana Ngusbrhan Namboze, Josephine
...
Published in
BMC Complementary Medicine and Therapies
Background Despite the growing conventional healthcare coverage in Eritrea, traditional medicine (TM) remains an essential source of healthcare service to the population. This study, therefore, aims at exploring the attitude, societal dependence, and pattern of TM use of the Gash-Barka community. Methods A cross-sectional study was conducted betwee...
Lin, Shun-Ku Wu, Chien-Tung Chou, Hui-Jer Liu, Chia-Jen Ko, Fu-Yang Huang, Ching-Hsuan Lai, Jung-Nien
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BMC Complementary Medicine and Therapies
Background Large-scale epidemics have changed people’s medical behavior, and patients tend to delay non-urgent medical needs. However, the impact of the pandemic on the use of complementary and alternative medicine remains unknown. Methods This retrospective study aimed to analyze the changes in the number of traditional Chinese medicine (TCM) pati...
