Zhou, Xueqing Xie, Yanli Zhao, Zhendong Fu, Wenyan
Published in
BMC Chemistry
Methods and experimentsIn this study, a functionalized multiwalled carbon nanotube (MWCNT)-coated solid-phase microextraction (SPME) fiber was developed for concentrating analytes in aqueous samples. Sodium deoxycholate (NaDC) was used as a dispersing agent for non-covalent modification of MWCNTs. The coating showed porous structure and large adsor...
Tsegay, Girmay Redi-Abshiro, Mesfin Chandravanshi, Bhagwan Singh Ele, Estifanos Mohammed, Ahmed M. Mamo, Hassen
Published in
BMC Chemistry
BackgroundThe fatty acids of green coffee beans are one of the major components that determine the quality of coffee. Fatty acids composition of green coffee beans is affected by soil composition and altitude of coffee plants. This study was aimed to evaluate the effect of altitude of the coffee plants on the composition of fatty acids in green cof...
Shaker, Ahmed M. M. Abdelall, Eman K. A. Abdellatif, Khaled R. A. Abdel-Rahman, Hamdy M.
Published in
BMC Chemistry
Three series of 2-(4-methylsulfonylphenyl) indole derivatives have been designed and synthesized. The synthesized compounds were assessed for their antimicrobial, COX inhibitory and anti-inflammatory activities. Compound 7g was identified to be the most potent antibacterial candidate against strains of MRSA, E. coli, K. pneumoniae, P. aeruginosa, a...
Feng, Yin Shu, Jing Yao, Liangzhong Lan, Yutao Ye, Lianbao Mei, Wenjie Ding, Ying
Published in
BMC Chemistry
MiR-21, a non-coding miRNA with 22 nucleotides, plays an important part in the proliferation, invasion, and metastasis of tumor cells. The present study demonstrates that isomers of chiral ruthenium(II) complexes with alkynes (Λ-1 and Δ-1) were synthesized by Songogashira coupling reaction by using microwave-assisted synthetic technology. The isome...
Dhiman, Priyanka Malik, Neelam Khatkar, Anurag
Published in
BMC Chemistry
Neurodegenerative disorders follow numerous pathological ways concerning overexpression of monoamine oxidase and formation of reactive oxygen species. The computational design of the piperine derivatives has given the significant MAO inhibitors with considerable antioxidant potential. Molecular docking provided the mechanistic insight of the compou...
Xin, Zhen-Hui Meng, Ya-Li Jiang, Wen-Jing Li, Ya-Peng Ge, Li-Ping Zhang, Cun-Hui Liu, Lian-Na Kang, Yan-Fei
Published in
BMC Chemistry
With the improvement and advance in cancer diagnosis and treatment, the cancer is still a major cause of morbidity and mortality throughout the world. Obviously, new breakthroughs in therapies remain be urgent needed. In this work, we designed and synthesized the compound 1–4, namely resveratrol analogues with methylation of hydroxy distyrene, to f...
Sun, Chunlong Du, Wen Wang, Baoqin Dong, Bin Wang, Baogui
Published in
BMC Chemistry
Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides numerous advantages for the real-time in vivo monitoring of biological information in living subjects without the use of ionizing radiation. Near-infrared fluorescent (NIRF) dyes are widely used as fluorescent imaging probes. These fluorescent dyes remarkably decrease...
Zheng, Shijie Lin, Xiaomin Wu, Hanxiang Zhao, Chen Xu, Hanhong
Published in
BMC Chemistry
Phloem systemicity is a desirable property for insecticides to control sucking insects. However, the development of phloem systemic insecticides is challenging. One possible strategy is to link existed insecticides with endogenous substances so that the resulting conjugates can be transported by specific transporters into the phloem. In this study,...
Ahmad, Niyaz Ahmad, Rizwan Al Qatifi, Sadiq Alessa, Mahdi Al Hajji, Hassan Sarafroz, Md
Published in
BMC Chemistry
To formulate a nanoformulation (PLGA-NPs) and to improve brain bioavailability for thymoquinone (THQ) through intranasal (i.n.) drug delivery, using a newly UHPLC-PDA developed the method and validated. Five different THQ-PLGA-NPs (THQ-N1 to THQ-N5) were prepared by emulsion solvent evaporation method. A new UHPLC method developed and validated for...
Hussein, Essam M. Alsantali, Reem I. Morad, Moataz Obaid, Rami J. Altass, Hatem M. Sayqal, Ali Abourehab, Mohamed A. S. Elkhawaga, Amal A. Aboraia, Ahmed S. M. Ahmed, Saleh A.
...
Published in
BMC Chemistry
BackgroundThiazoles, thiazolidinones and azetidinones are highly ranked amongst natural and synthetic heterocyclic derivatives due to their great pharmaceutical potential.ResultsNew thiazolidinone and azetidinone class of bioactive agents based on 4-(2,7-dichloro-9H-fluoren-4-yl)thiazole moiety have been successfully synthesized. 4-(2,7-dichloro-9H...
