Thureau, Sébastien Marchesi, Vincent Vieillard, Marie-Hélène Perrier, Lionel Lisbona, Albert Leheurteur, Marianne Tredaniel, Jean Culine, Stéphane Dubray, Bernard Bonnet, Naïma
...
Published in
BMC Cancer
BackgroundStereotactic Body Radiation Therapy (SBRT) is an innovative modality based on high precision planning and delivery. Cancer with bone metastases and oligometastases are associated with an intermediate or good prognosis. We assume that prolonged survival rates would be achieved if both the primary tumor and metastases are controlled by loca...
Salerno, Elizabeth A. Gothe, Neha P. Fanning, Jason Peterson, Lindsay L. Colditz, Graham A. McAuley, Edward
Published in
BMC Cancer
BackgroundSupervised physical activity interventions improve functional health during cancer survivorship, but remain costly and inaccessible for many. We previously reported on the benefits of a DVD-delivered physical activity program (FlexToBa™) in older adults. This is a secondary analysis of the intervention effects among cancer survivors in th...
Cubiella, Joaquín González, Antía Almazán, Raquel Rodríguez-Camacho, Elena Zubizarreta, Raquel Peña-Rey Lorenzo, Isabel
Published in
BMC Cancer
BackgroundAlthough colorectal cancer (CRC) screening programs reduce CRC incidence and mortality, they are associated with risks in healthy subjects. However, the risk of overtreatment and overdiagnosis has not been determined yet. The aim of this study was to report the surgery rates in patients with nonmalignant lesions detected within the first ...
Routila, Johannes Suvila, Karri Grénman, Reidar Leivo, Ilmo Westermarck, Jukka Ventelä, Sami
Published in
BMC Cancer
BackgroundCurrently, no clinically useful biomarkers for radioresistance are available in head and neck squamous cell carcinoma (HNSCC). This study assesses the usefulness of Cell Line Microarray (CMA) method to enhance immunohistochemical screening of potential immunohistochemical biomarkers for radioresistance in HNSCC cell lines.MethodsTwenty-ni...
Brito, Ariadna Merle, Candice Lagarde, Pauline Faustin, Benjamin Devin, Anne Lartigue, Lydia Chibon, Frederic
Published in
BMC Cancer
BackgroundCell-to-cell fusion is emerging as a key element of the metastatic process in various cancer types. We recently showed that hybrids made from the spontaneous merging of pre-malignant (IMR90 E6E7, i.e. E6E7) and malignant (IMR90 E6E7 RST, i.e. RST) mesenchymal cells recapitulate the main features of human undifferentiated pleomorphic sarco...
Li, Xiaoran Xu, Chen Yu, Yang Guo, Yan Sun, Hongzan
Published in
BMC Cancer
BackgroundLymphovascular space invasion is an independent prognostic factor in early-stage cervical cancer. However, there is a lack of non-invasive methods to detect lymphovascular space invasion. Some researchers found that Tenascin-C and Cyclooxygenase-2 was correlated with lymphovascular space invasion. Radiomics has been studied as an emerging...
Asano, Kenichiro Fumoto, Toshio Matsuzaka, Masashi Hasegawa, Seiko Suzuki, Naoya Akasaka, Kenichi Katayama, Kosuke Kamataki, Akihisa Kurose, Akira Ohkuma, Hiroki
...
Published in
BMC Cancer
BackgroundThis investigator-initiated, open-label, single-arm, single-institute study was conducted to investigate the effectiveness of induction combination chemoradiotherapy and long-term maintenance therapy with temozolomide (TMZ) plus interferon (IFN)-β for glioblastoma.MethodsThe initial induction combination chemoradiotherapy comprised radiot...
Ginzac, Angeline Dupic, Guillaume Brun, Lucie Molnar, Ioana Casile, Mélanie Durando, Xavier Verrelle, Pierre Lemaire, Jean-Jacques Khalil, Toufic Biau, Julian
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Published in
BMC Cancer
BackgroundSurgery is an important therapeutic option for brain metastases. Currently, postoperative stereotactic radiosurgery (SRT) leads to 6-month and 1-year local control estimated at 70 and 62% respectively. However, there is an increased risk of radio-necrosis and leptomeningeal relapse. Preoperative SRT might be an alternative, providing loca...
Cavalloni, Giuliana Peraldo-Neia, Caterina Massa, Annamaria Bergamini, Carlo Trentini, Alessandro De Rosa, Giovanni Daniele, Lorenzo Ciccosanti, Fabiola Cervellati, Carlo Leone, Francesco
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Published in
BMC Cancer
BackgroundCholangiocarcinoma (CCA) is an aggressive disease with poor prognosis. A molecular classification based on mutational, methylation and transcriptomic features could allow identifying tailored therapies to improve CCA patient outcome. Proteomic remains partially unexplored; here, we analyzed the proteomic profile of five intrahepatic chola...
Wu, Jie Wang, Yu-Chen Luo, Wen-Jie Bo-Dai, Ye, Ding-Wei Zhu, Yi-Ping
Published in
BMC Cancer
BackgroundPrimary urethral carcinoma (PUC) is a rare genitourinary malignancy with a relatively poor prognosis. The aim of this study was to examine the impact of surgery on survival of patients diagnosed with PUC.MethodsA total of 1544 PUC patients diagnosed between 2004 and 2016 were identified based on the SEER database. The Kaplan-Meier estimat...
