Huang, Weijun Ye, Jieyi Qiu, Yide Peng, Weiwei Lan, Ninghui Cui, Weizhen Huang, Ting Ou, Yinghui Li, Yingjia
Published in
BMC Cancer
BackgroundDefinitive diagnosis of peripheral pulmonary lesions (PPLs) depends on the histological analysis of the pleural biopsy sample. Ultrasound (US)-guided sampling is now standard practice in the clinical setting. However, determining a suitable needle size and sampling times to improve the efficacy and safety of the biopsy remains challenging...
Wang, Tuo Sun, Yao Xiong, Zichao Wu, Jiamin Ding, Xiaoying Guo, Xiaoye Shao, Yuan
Published in
BMC Cancer
BackgroundAstrocytoma is a common type of central nervous system tumor. In this study, we investigated the correlation between ST6GAL1 and CYP19A1 polymorphisms and the risk and prognosis of astrocytoma.MethodsA total of 365 astrocytoma patients and 379 healthy controls were genotyped using the Agena MassARRAY system. The correlation between ST6GAL...
Zhang, Hao Li, Jingtao Zeng, Wenting
Published in
BMC Cancer
BackgroundThe fragility index (FI) of trial results can provide a measure of confidence in the positive effects reported in randomized controlled trials (RCTs). The aim of this study was to calculate the FI of RCTs supporting HCC treatments.MethodsA methodological systematic review of RCTs in HCC treatments was conducted. Two-arm studies with rando...
Amin, Saber Baine, Michael Meza, Jane Lin, Chi
Published in
BMC Cancer
BackgroundCancer patients with brain metastases (BMs) require multidisciplinary care, and treatment facility may play a role. This study aimed to investigate the impact of receiving treatment at academic centers on the overall survival (OS) of cancer patients with brain metastases (BMs) regardless of the primary cancer site.MethodsThis retrospectiv...
Chen, Ke Pan, Yu Huang, Chao-jie Chen, Qi-long Zhang, Ren-chao Zhang, Miao-zun Wang, Guan-yu Wang, Xian-fa Mou, Yi-ping Yan, Jia-fei
...
Published in
BMC Cancer
BackgroundPancreatic ductal adenocarcinoma (PDAC) is a leading causes of cancer mortality worldwide. Currently, laparoscopic pancreatic resection (LPR) is extensively applied to treat benign and low-grade diseases related to the pancreas. The viability and safety of LPR for PDAC needs to be understood better. Laparoscopic distal pancreatectomy (LDP...
Rades, Dirk Witteler, Jaspar Olbrich, Denise Trillenberg, Peter Schild, Steven E. Tvilsted, Soeren Kjaer, Troels W.
Published in
BMC Cancer
BackgroundGliomas are often associated with symptoms including seizures. Most patients with high-grade gliomas are treated with radiotherapy or radio-chemotherapy. Since irradiation causes inflammation, it may initially aggravate symptoms. Studies focusing on seizure activity during radiotherapy for gliomas are not available. Such knowledge may imp...
Wang, Liwei Chen, Fu Liu, Rui Shi, Lei Zhao, Guosheng Yan, Zhengjian
Published in
BMC Cancer
BackgroundImmunotherapy is a vital component in cancer treatment. However, due to the complex genetic bases of cancer, a clear prediction index for efficacy has not been established. Tumor mutation burden (TMB) is one of the essential factors that affect immunotherapeutic efficacies, but it has not been determined whether the mutation is associated...
Xing, Qianwei Zeng, Tengyue Liu, Shouyong Cheng, Hong Ma, Limin Wang, Yi
Published in
BMC Cancer
BackgroundThe role of glycolysis in tumorigenesis has received increasing attention and multiple glycolysis-related genes (GRGs) have been proven to be associated with tumor metastasis. Hence, we aimed to construct a prognostic signature based on GRGs for clear cell renal cell carcinoma (ccRCC) and to explore its relationships with immune infiltrat...
Li, Sijian Yang, Tengyu Xiang, Yang Li, Xiaoyan Zhang, Limeng Deng, Shan
Published in
BMC Cancer
BackgroundMalignant struma ovarii (MSO) is a unique type of ovarian malignancy that data on the survival outcome is limited and management strategy remains controversial due to its extreme rarity.MethodsTo investigate the clinical characteristics and treatment options in patients with MSO confined to the ovary, while also evaluating the recurrent-f...
Vania, Leila Morris, Gavin Ferreira, Eloise Weiss, Stefan F. T.
Published in
BMC Cancer
BackgroundThe 37 kDa/67 kDa laminin receptor (LRP/LR) is involved in several tumourigenic-promoting processes including cellular viability maintenance and apoptotic evasion. Thus, the aim of this study was to assess the molecular mechanism of LRP/LR on apoptotic pathways in late stage (DLD-1) colorectal cancer cells upon siRNA-mediated down-regulat...
