Huang, Yu Wang, Xiansong Wu, Fashuai Lu, Yuqing Liang, Gengtian Liu, Aiguo
Published in
Audiology and Neurotology
Objective: The aim of this study was to investigate sclerostin (SOST) expression in a rat model of experimental tympanosclerosis (TS) and its possible role in the formation of TS. Materials and Methods: Thirty-four SD rats were randomly divided into 2 groups: experimental group (n = 17) and normal group (n = 17). The left tympanic cavities in the e...
Andries, Ellen Gilles, Annick Topsakal, Vedat Vanderveken, Olivier M. Van de Heyning, Paul Van Rompaey, Vincent Mertens, Griet
Published in
Audiology and Neurotology
Cochlear implants (CI) have increasingly been adopted in older adults with severe to profound sensorineural hearing loss as a result of the growing and aging world population. Consequently, researchers have recently shown great interest in the cost-effectiveness of cochlear implantation and its effect on quality of life (QoL) in older CI users. The...
Magen, Eli Blum, Idan Waitman, Dan Andrey Kahan, Natan Forer, Boaz
Published in
Audiology and Neurotology
Objectives: Autoimmune inner ear disease (AIED) is a distinct clinical entity from sudden sensorineural hearing loss. The purpose of this study was to investigate the clinical characteristics of AIED in patients with selective IgA deficiency (sIgAD). Materials and Methods: This retrospective observational study was based on data from the Leumit Hea...
Strübing, Ira Gröschel, Moritz Schwitzer, Susanne Ernst, Arne Fröhlich, Felix Jiang, Dan Boyle, Patrick Basta, Dietmar
Published in
Audiology and Neurotology
Introduction: The preservation of residual hearing has become an important consideration in cochlear implant (CI) recipients in recent years. It was the aim of the present animal experimental study to investigate the influence of a pretreatment with near-infrared (NIR) light on preservation of sensory hair cells and residual hearing after cochlear ...
Coutinho da Silva, Juliana Schmidt Goffi-Gomez, Maria Valéria Tsuji, Robinson Koji Bento, Ricardo Brito Neto, Rubens
Published in
Audiology and Neurotology
Background: The spread of excitation (SOE) and auditory nerve recovery function (REC) are objective measures recorded by neural response telemetry and may interfere in cochlear implant (CI) stimulation. Objective: To analyze and correlate SOE with the refractory periods in subjects with pre- and postlingual deafness implanted with different electro...
Peñaranda, Daniel Moreno, Sergio Montes, Felipe Garcia, Juan Manuel Rico, Zulehima Peñaranda, Augusto
Published in
Audiology and Neurotology
Objective: To evaluate the short-term (postoperative), medium-term (5 years), and long-term (10 and 15 years) audiometric results of patients who underwent stapedotomy and to determine specific factors associated with better postoperative outcomes. Methods: This study is a retrospective case review of 486 ears with surgically confirmed stapes fixat...
Tan, Jingqian Luo, Jia Wang, Xin Jiang, Yanbing Zeng, Xiangli Chen, Shixiong Li, Peng
Published in
Audiology and Neurotology
Introduction: Auditory brainstem response (ABR) is one of the commonly used methods in clinical settings to evaluate the hearing sensitivity and auditory function. The current ABR measurement usually adopts click sound as the stimuli. However, there may be partial ABR amplitude attenuation due to the delay characteristics of the cochlear traveling ...
Lucidi, Daniela Paludetti, Gaetano Settimi, Stefano De Corso, Eugenio Picciotti, Pasqualina Maria Sergi, Bruno
Published in
Audiology and Neurotology
Introduction: Stapes surgery is a safe procedure, with favourable hearing outcome. The objective of the study is to assess the long-term hearing results, addressing the bone conduction (BC) decay and the need for hearing aids in otosclerosis patients. Methods: We enrolled patients who underwent stapes surgery by means of stapedectomy or stapedotomy...
Tekin, Ahmet M. de Ceulaer, Geert Govaerts, Paul Bayazit, Yıldırım Wuyts, Wim Van de Heyning, Paul Topsakal, Vedat
Published in
Audiology and Neurotology
Background and Objectives: A rare type of nonsyndromic autosomal recessive hereditary hearing loss is caused by pathogenic mutations in the TRIOBP gene mostly involving exons 6 and 7. These mutations cause hearing loss originating from dysfunction of sensory inner ear hair cells. Of all the affected siblings, 2 brothers and 1 sister, part of an Afg...
Na, Gina Lee, Jeon Mi Lee, Hyun Jin Jeong, Yeonsu Jung, Jinsei Choi, Jae Young
Published in
Audiology and Neurotology
Introduction: Fluctuating hearing loss is a distinctive feature caused by SLC26A4 variants. We investigated whether cochlear implantation had protective or deleterious effect on hearing fluctuation in patients with biallelic SLC26A4 variants. Methods: Patients with biallelic SLC26A4 variants (N = 16; age = 10.24 ± 9.20 years) who had unilateral coc...