Published in Atherosclerosis
Mechanisms of SARS-CoV-2-related vasculitis/endotheliitis. Covid-19 may affect the endothelium and smooth muscle cells of the arterial and venous wall at different levels and through multiple ways, namely: inflammation/immune response, hypercoagulability and increased vascular reactivity. ACE-2: angiotensin-converting enzyme 2; Angpt: angiopoietin;...
Published in Atherosclerosis
• Familial hypercholesterolemia (FH) patients are potentially at high risk for COVID-19 complications in the acute and chronic phases of the infection. • As statins are likely of benefit, FH patients with COVID-19 who use statins should continue with this therapy. • In FH patients, the focus should be on the effective lowering of high LDL-cholester...
Published in Atherosclerosis
Using a nationwide epidemiological database, we aimed to clarify the association of fasting plasma glucose (FPG) with subsequent cardiovascular disease (CVD) risk among young adults. Medical records of 1,180,062 young adults (20-49 years old) without a prior history of CVD and who were not taking antidiabetic medications were extracted from the Jap...
Published in Atherosclerosis
Mobile technology-based solutions present promising effects against cardiovascular diseases. Long-term follow-up in mobile phone-based interventions has not yet been elucidated as a primary prevention technique for cardiovascular diseases. The objective of the present trial is to evaluate the effectiveness of lifestyle intervention on the change in...
Published in Atherosclerosis
Sudden death is one of the most common causes of death among patients on hemodialysis. Although hyperphosphatemia is a well-known risk factor for cardiovascular and all-cause deaths, the studies focusing on the relationship between serum phosphate levels and the risk of sudden death are limited. This study aimed to clarify the relationship between ...
Published in Atherosclerosis
Published in Atherosclerosis
The transition of macrophage to foam cells is a major hallmark of early stage atherosclerotic lesions. This process is characterized by the accumulation of large cytoplasmic lipid droplets containing large quantities of cholesterol esters (CE), triacylglycerol (TAG) and phospholipid (PL). Although cholesterol and CE metabolism during foam cell form...
Published in Atherosclerosis
Transcutaneous oxygen pressure (TcpO2) is used in patients with suspected critical limb ischemia (CLI). Sinusoidal changes (SC~) in TcpO2 are found in patients with Cheyne-Stokes respiration (CSR). We aimed to determine the characteristics of TcpO2 changes at rest in patients with suspected CLI, define the objective criteria for SC ~ TcpO2 patterns...
Published in Atherosclerosis
The pattern of intracranial internal carotid artery calcification (ICAC) has been identified as an effect modifier of endovascular treatment in patients with acute ischemic stroke, but it is unclear whether it modifies the effect of intravenous thrombolysis. The purpose of this study was to evaluate the association between intravenous thrombolysis ...
Published in Atherosclerosis
