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Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy.

Published in Atherosclerosis

Acromegalic patients have coronary microvascular dysfunction that may be restored by therapy with somatostatin analogues. IGF-1 independently correlates with the coronary microvascular impairment, suggesting the pivotal role of this hormone in explaining the increased cardiovascular risk in acromegaly.

Comparison of cardiovascular outcomes and all-cause mortality in patients with chronic hepatitis B and C: A 13-year nati...

Published in Atherosclerosis

In patients with chronic viral hepatitis, subjects with HCV infection had a significantly higher risk of composite arterial events and all-cause mortality compared with those with HBV infection.

PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions.

Published in Atherosclerosis

Administration of PCSK9 antibody significantly alters the lipid composition of plasma and lipoprotein particles. These changes further shed light on the link between anti-PCSK9 therapies and cardiovascular risk.

Different effects of apnea during rapid eye movement period on peripheral arterial stiffness in obstructive sleep apnea....

Published in Atherosclerosis

AHI-REM was independently correlated with a peripheral arterial stiffness index, CI. AHI-REM may be a suitable surrogate marker for predicting peripheral arterial stiffness in OSA patients.

High density lipoprotein with apolipoprotein C-III is associated with carotid intima-media thickness among generally hea...

Published in Atherosclerosis

HDL apoC-III is a promising target for atherosclerosis prevention and treatment.

The natural history of phytosterolemia: Observations on its homeostasis.

Published in Atherosclerosis

This evidence of a link with age leads us to propose that an age-related change in cholesterol and sterol homeostasis occurs at puberty in phytosterolemia and that the change is due to high sterol and/or stanol levels causing feedback inhibition of sterol regulatory element-binding protein (SREBP-2) processing. This would explain the well-documente...

Antithrombin levels are associated with the risk of first and recurrent arterial thromboembolism at a young age.

Published in Atherosclerosis

Individuals with relatively low antithrombin levels have an increased risk for ATE at a younger age. CHD patients with low antithrombin levels, especially women, have a higher risk of recurrent cardiac events.

Stroke outcome is associated with baseline renal function: A risk factor that matters!

Published in Atherosclerosis

Environment-wide association study to identify novel factors associated with peripheral arterial disease: Evidence from ...

Published in Atherosclerosis

Our systematic evaluation provides new knowledge on the complex array of environmental correlates of PAD. These identified correlates need to be probed in further observational and interventional studies.

Differential effects of brachial and central blood pressures on circulating levels of high-sensitivity cardiac troponin ...

Published in Atherosclerosis

Circulating levels of hs-cTnI increase with increasing brachial and central BP, but the effect of central BP was greater in subjects with higher rAI. This indicates that central BP may have a strong effect on silent myocardial damage, assessed as increased circulating hs-cTnI, particularly in subjects with increased arterial stiffness.