Sun, Wenji Wang, Shigang Zhang, Jiafeng Arias, Katherin Griffith, Bartley P Wu, Zhongjun J
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Artificial organs
High mechanical shear stresses (HMSS) can cause damage to blood, which manifests as morphologic changes, shortened life span, biochemical alterations, and complete rupture of blood cells and proteins, leading to the alterations of normal blood function. The aim of this study is to determine the state of neutrophil activation and function alteration...
Imamura, Teruhiko Narang, Nikhil Combs, Pamela Siddiqi, Umar Mirzai, Saeid Stonebraker, Corinne Bullard, Heather Simone, Pamela Jeevanandam, Valluvan
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Artificial organs
Worsening systemic congestion is often the central trigger of hospitalization in patients with heart failure. However, accurate assessment of congestion is challenging. The prognostic impact of systemic congestion following durable continuous-flow left ventricular assist device (LVAD) implantation remains unknown. Consecutive patients who received ...
Zhang, Jing-Yu Zhang, Hao-Ran Tian, Dong-Mu Wang, Feng Ren, Zhi-Peng Hu, Yong-Cheng
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Artificial organs
We aimed to evaluate the biomechanical contact characteristics of rotating hinge knee (RHK) prostheses with different motion axial systems. We performed finite element (FE) analyses to investigate and compare the peak contact stress and contact location on tibial insert and bushing during a gait cycle. The biaxial (BA) system and spherical center a...
Seetharaman, Rajmohan V Rane, Jitesh R Dingre, Niraj S
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Artificial organs
Organ donation is a lifesaving treatment option for patients with end-organ damage. However, many patients are unable to avail this option due to the low availability of viable organs for transplantation. The availability of donor organs can be improved by increasing awareness and resolving organ donation misconceptions among the general population...
Zayat, Rashad Kalverkamp, Sebastian Grottke, Oliver Durak, Koray Dreher, Michael Autschbach, Rüdiger Marx, Gernot Marx, Nikolaus Spillner, Jan Kersten, Alex
...
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Artificial organs
The role of extracorporeal membrane oxygenation (ECMO) in the management of critically ill COVID-19 patients remains unclear. Our study aims to analyze the outcomes and risk factors from patients treated with ECMO. This retrospective, single-center study includes 17 COVID-19 patients treated with ECMO. Univariate and multivariate parametric surviva...
Jäckel, Markus Rilinger, Jonathan Lang, Corinna Nadine Zotzmann, Viviane Kaier, Klaus Stachon, Peter Biever, Paul Marc Wengenmayer, Tobias Duerschmied, Daniel Bode, Christoph
...
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Artificial organs
Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is used to sustain blood oxygenation and decarboxylation in severe acute respiratory distress syndrome (ARDS). It is under debate if V-V ECMO is as appropriate for coronavirus disease 2019 (Covid-19) ARDS as it is for influenza. In this retrospective study, we analyzed all patients with con...
Rodrigues, Isabella C P Pereira, Karina D Freire Woigt, Luiza Jardini, André L Luchessi, Augusto D Lopes, Éder S N Webster, Thomas J Gabriel, Laís P
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Artificial organs
Tubular polymer scaffolds based on tissue engineering techniques have been studied as potential alternatives for vascular regeneration implants. The blood vessels of the cardiovascular system are mainly fibrous, composed of collagen (Col) and elastin (El), and its inner layer consists of endothelial cells. In this work, Col and El were combined wit...
Rowlands, Grant W Antaki, James F
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Artificial organs
Biocompatibility of ventricular assist devices (VADs) has been steadily improving, yet the rate of neurological events remains unacceptably high. Recent speculation for elevated stroke rates centers on ingestion of thrombi originating upstream of the pump, such as in the ventricle or left atrial appendage. These thrombi may be ejected by the VAD or...
Christian-Miller, Nathaniel Hadaya, Joseph Nakhla, Morcos Sanaiha, Yas Madrigal, Josef Emami, Sara Cale, Mario Sareh, Sohail Benharash, Peyman
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Artificial organs
Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes of ECLS is poorly defined. The purpose of the study was to compare in-hospital mortality, resource use, complications, and readmissions in obese versus non-obese patients receiving ECLS. We performed a ret...
Meng, Zhuangyuan Ma, Tao Cai, Yunhan Liu, Xudong Wang, Shengzhang Dong, Zhihui Fu, Weiguo
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Artificial organs
Retrograde type A dissection after thoracic endovascular aortic repair has been a major drawback of endovascular treatment. This study investigated the biomechanical mechanism of stent-graft-induced new lesions after implantation and analyzed the relationship between radial force and spring-back force of the stent-graft when it was implanted virtua...