Biomimetic cartilage scaffold with orientated porous structure of two factors for cartilage repair of knee osteoarthriti...
Published in Artificial Cells Nanomedicine and Biotechnology
A dual-layer biomimetic cartilage scaffold was prepared by mimicking the structural design, chemical cues and mechanical characteristics of mature articular cartilage. The surface layer was made from collagen (COL), chitosan (CS) and hyaluronic acid sodium (HAS). The transitional layer with microtubule array structure was prepared with COL, CS and ...