Karczewski, Daniel Scholz, Johann Hipfl, Christian Akgün, Doruk Gonzalez, Marcos R Hardt, Sebastian
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Archives of orthopaedic and trauma surgery
While gram negative (GN) periprosthetic joint infections (PJI) have previously been described as difficult to treat pathogens with high rates of reinfection, limited investigations have addressed midterm outcomes and risk of infection persistence by the same pathogen. This study analyzed (1) baseline demographics, treatment strategy, and midterm ou...
Egerci, Omer Faruk Yapar, Aliekber Dogruoz, Fırat Selcuk, Huseyin Kose, Ozkan
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Archives of orthopaedic and trauma surgery
The increasing frequency of total hip (THA) and knee arthroplasties (TKA) is marred by the rise in periprosthetic joint infections (PJIs) and surgical site infections (SSIs), with PJIs incurring costs over $1.62 billion as of 2020 and individual case management averaging $90,000. SSIs additionally burden the U.S. healthcare economy with billions in...
Ghaseminejad-Raeini, Amirhossein Esmaeili, Sina Ghaderi, Ali Sharafi, Amirmohammad Azarboo, Alireza Hoveidaei, Amir Human Shafiei, Seyyed Hossein Golbakhsh, Mohammadreza
Published in
Archives of orthopaedic and trauma surgery
Total joint arthroplasty (TJA) is a common procedure that improves the quality of life for severe arthritis patients. The rising demand for TJA places enormous financial strain on the world's healthcare systems, which is exacerbated by postoperative readmissions for complications such as periprosthetic joint infections (PJIs). We conducted a system...
Kloos, Johannes Vandenneucker, Hilde Berger, Pieter
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Archives of orthopaedic and trauma surgery
Prevalence of unexpected positive intraoperative cultures (UPIC) in revision total knee arthroplasty (TKA) is reported to be 8.32% with largely varying findings in individual studies (5.92-62.07%) due to a heterogeneity in preoperative diagnostic work-up and diagnostic criteria for periprosthetic joint infection (PJI). When diagnosed as unsuspected...
Brenneis, Marco Flevas, Dimitrios A Gayle, Lloyd B Boettner, Friedrich Sculco, Peter K Westrich, Geoffrey H
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Archives of orthopaedic and trauma surgery
Options for soft tissue coverage in revision total knee arthroplasty (rTKA) range from primary wound closure to complex muscle flap reconstructions. The purpose of this study was to investigate the institutional experience of wound coverage options for complex soft tissue defects in rTKA. 77 patients undergoing rTKA with complex wound closure by a ...
Hoveidaei, Amir Human Ghaseminejad-Raeini, Amirhossein Esmaeili, Sina Movahedinia, Mohammad Karbasi, Shima Khonji, Mohammad Saeid Nwankwo, Basilia Onyinyechukwu Shrestha, Ashesh Conway, Janet D
Published in
Archives of orthopaedic and trauma surgery
Periprosthetic joint infection (PJI) poses a significant challenge in total knee arthroplasty (TKA), with recurrence rates as high as 14-28%, leading to substantial morbidity and treatment costs. When conventional treatments fail, knee fusion and above-the-knee amputation (AKA) emerge as alternative options. Existing literature offers conflicting v...
Hauer, Georg Rasic, Laura Klim, Sebastian Leitner, Lukas Leithner, Andreas Sadoghi, Patrick
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Archives of orthopaedic and trauma surgery
A decade ago, a comprehensive study was conducted to investigate the reasons for revision surgeries and their respective frequencies in cases of total hip arthroplasty (THA) and total knee arthroplasty (TKA) based on a complication-based analysis of joint replacement registries. The aim of the present study was to determine whether the causes and r...
Russo, Antonio Migliorini, Filippo Giustra, Fortunato Bosco, Francesco Massè, Alessandro Burastero, Giorgio
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Archives of orthopaedic and trauma surgery
Septic arthritis (SA) is a rare but significant clinical challenge in orthopedics that can impact patients' quality of life. This study aims to examine the clinical outcomes of patients undergoing two-stage total joint replacement (TJR) in hip and knee SA and analyze potential predictors of treatment failure. A retrospective analysis was conducted ...
Poursalehian, Mohammad Lotfi, Mohadeseh Mortazavi, Seyed Mohammad Javad
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Archives of orthopaedic and trauma surgery
Accurate diagnosis of latent infections prior to conversion total hip arthroplasty (THA) following internal fixation of femoral neck fractures is crucial for successful surgical outcomes. This systematic review aimed to provide a comprehensive evaluation of the current literature regarding the diagnosis of latent infections before conversion THA. S...
Festa, E Ascione, T Di Gennaro, D De Mauro, D Mariconda, M Balato, G
Published in
Archives of orthopaedic and trauma surgery
Calprotectin is a protein endowed with antimicrobial properties, rendering it a distinctive marker for infection. Two methods are currently available for the assay of calprotectin: the enzyme-linked immunosorbent assay (ELISA) and the lateral flow test (LFT). We aimed to assess the diagnostic accuracy of synovial fluid calprotectin and to compare t...