Sena, Kotaro Furue, Kirara Setoguchi, Fumiaki Noguchi, Kazuyuki
Published in
Archives of Oral Biology
Objective The aim of this in vitro study was to investigate the expression of SARS-CoV-2 entry and processing genes in human gingival fibroblasts (HGnF) following treatment with Porphyromonas gingivalis -derived lipopolysaccharide (PgLPS) or inflammatory cytokines/mediators. Design We assessed the expression of SARS-CoV-2 entry and processing genes...
Hopkins, Mark Boesch, Christine Lansdall, Matthew Mullen, Conor Mighell, Alan Pavitt, Sue Sarkar, Anwesha
Published in
Archives of Oral Biology
Objective This study sought to examine the effects of moderate intensity exercise on lubrication performance of saliva. We hypothesized that exercise would result in enhanced salivary lubricity by direct sympathetic stimulation of the salivary proteins. Study design In total, 11 healthy young pre-menopausal female participants (mean age: 24.4 ± 1.8...
Walter, C. Klein, M. O. Pabst, A. Al-Nawas, B. Duschner, H. Ziebart, T.
Published in
Clinical Oral Investigations
Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a side effect primarily in patients receiving highly potent nitrogen-containing bisphosphonates. The exact etiopathology is unknown. In addition to reduced bone remodeling, there may also be an impact on soft tissues. The impact of nitrogen- (ibandronate, pamidronate, zoledronate) and ...
Pimentel, S.P. Casati, M.Z. Cirano, F.R. Ribeiro, F.V. Casarin, R.V. Kirsten, T.B. Chaves-Kirsten, G.P. Duarte, P.M. Bernardi, M.M.
Published in
Neuroimmunomodulation
Objective: Our objective was to verify whether prenatal maternal periodontitis is a risk factor for the development of central nervous system disorders in rats. Methods: Periodontitis was induced by placing a ligature around the upper and lower first molars in 9 female Wistar rats (experimental group); 9 rats were left unligated (control group). Th...
Kubota, T. Maruyama, S. Abe, D. Tomita, T. Morozumi, T. Nakasone, N. Saku, T. Yoshie, H.
Published in
Archives of Oral Biology
ObjectivePeriodontitis involves periodontal tissue destruction and is associated with chronic inflammation and ageing. Periodontitis has recently been recognised as a risk factor for Alzheimer's disease (AD). We showed upregulation of molecules in the AD pathway including amyloid beta (A4) precursor protein (APP), a key gene in AD, interleukin-1 be...
Watanabe, Teppei Yasue, Akihiro Tanaka, Eiji
Published in
Archives of Oral Biology
BackgroundWe reported previously that hypoxia inducible factor (HIF)-1α was not degraded under normoxic condition with transforming growth factor (TGF)-β1 stimulation in human periodontal ligament (PDL) cells; however, the role of HIF-1α has been unclear. Recently, HIF-1α, working together with TGF-β1, has been reported to promote extracellular mat...
Funaki, Yukiha Hiranuma, Maya Shibata, Mai Kokai, Satoshi Ono, Takashi
Published in
Archives of Oral Biology
ObjectiveNasal obstruction during growth changes craniofacial morphology and function. However, the etiological mechanisms of these changes are unknown. The aim of the present study was to investigate the effects of nasal obstruction during growth on the maturation of the jaw-opening reflex (JOR) using an electrophysiological technique. We focused ...
Ryynänen, Hanna Sahlberg, Carin Lukinmaa, Pirjo-Liisa Alaluusua, Satu
Published in
Archives of Oral Biology
ObjectiveOur aim was to study the effect of high temperature (39°C) corresponding to fever on the development of enamel in cultured mouse molars. DesignFor morphological studies mandibular molar blocks from E18 mice were cultured for 11 days. After three days at 37°C the teeth were exposed to 39°C for three or five days and returned to 37°C. At the...
Marchini, Adriana Mathias Pereira da Sil... Gonçalves, Lucélia Lemes Salgado, Miriane Carneiro Machado do Prado, Renata Falchete Marchini, Leonardo Carvalho, Yasmin Rodarte da Rocha, Rosilene Fernandes
Published in
Archives of Oral Biology
ObjectiveStudies suggest that chronic alcoholism as well as oestrogen deficiencies may affect bones in general, including alveolar bone and, by doing so, increase individuals’ susceptibility to develop progressive periodontal disease. This paper aims to verify the influence of chronic alcoholism and/or oestrogen deficiencies in the apoptosis of bon...
Drago, Lorenzo Nicola, Lucia Iemoli, Enrico Banfi, Giuseppe De Vecchi, Elena
Published in
BMC Research Notes
BackgroundOral administration of probiotics is known to modulate cytokines profile not only locally, but also systemically. Four strains of Lactobacillus salivarius, LDR0723, BNL1059, RGS1746 and CRL1528, were evaluated for their ability to modulate release of pro- and anti-inflammatory cytokines.FindingsStrains were assessed for effects on product...
