MacGibeny, Margaret A. Wassef, Cindy
Published in
Archives of Dermatological Research
The COVID-19 pandemic has swept the globe with more than 2,000,000 confirmed cases of SARS-CoV-2 infection in 184 countries and territories. According to the Centers for Disease Control and Prevention (CDC), two crucial actions can reduce the risk of person-to-person viral transmission: frequent hand washing and surface decontamination with specifi...
Schneider, Samantha L. Council, Martha Laurin
Published in
Archives of Dermatological Research
The novel coronavirus (SARS-CoV-2) pandemic has necessitated a dramatic shift in how our dermatology residents and fellows are educated. Distance or online learning has become the norm, and several national and international academic societies have combined resources to assure that continuing medical education occurs during this difficult time. The...
Sabry, Dina Aboraia, Nesreen Samir, Mai
Published in
Archives of Dermatological Research
Interleukin 17 (IL-17) is one of the pro-inflammatory cytokine. Psoriasin is a noticeably over-expressed protein found in the skin lesions of psoriatic patients. Our current study was planned to examine the association of (− 947 A/G) single nucleotide polymorphism (SNP) in IL-17RA promoter region (rs4819554) with psoriasis susceptibility in Egyptia...
Limandjaja, Grace C Waaijman, Taco Roffel, Sanne Niessen, Frank B Gibbs, Susan
Published in
Archives of dermatological research
Several abnormalities have been reported in the peripheral blood mononuclear cells of keloid-forming patients and particularly in the monocyte cell fraction. The goal of this in vitro study was to determine whether monocytes from keloid-prone patients contribute to the keloid phenotype in early developing keloids, and whether monocyte differentiati...
Bage, Timothy Edymann, Trevor Metcalfe, Anthony D Dheansa, Baljit Mbundi, Lubinda
Published in
Archives of dermatological research
In this study, we characterised the effect that seeding keratinocytes on the papillary and reticular dermis had on the extracellular matrix and tissue integrity ex vivo. Human skin explants from consented patients (n = 6) undergoing routine surgery were cultured at a liquid-air interface, dermal-side up, and autologous keratinocytes seeded on the e...
Nong, Xiaolin Rajbanshi, Girju Chen, Ling Li, Jiaquan Li, Zhan Liu, Taotao Chen, Shihai Wei, Gao Li, Jushang
Published in
Archives of Dermatological Research
Artesunate (ART) is the derivative of artemisinin isolated from the traditional Chinese medicine qinghao . Although several studies reported the efficiency of artesunate in the treatment of malaria, inhibiting fibroblasts and collagen synthesis, the association between artesunate and scar formation is unclear. The research was designed to study the...
Liu, Chun-Lei Yuan, Zhi-Yong
Published in
Archives of dermatological research
Keloid resection followed by adjuvant radiotherapy is the most efficacious treatment for keloids. However, for earlobe keloids, an optimal protocol for the total dose and fractions of adjuvant radiation has not yet been established. We retrospectively analyzed the efficacy and safety of immediate three-fraction electron radiotherapy after operation...
Sławińska, Martyna Zabłotna, Monika Gleń, Jolanta Lakomy, Joanna Nowicki, Roman J. Sobjanek, Michał
Published in
Archives of Dermatological Research
Basal cell carcinoma (BCC) environment consists of stromal and inflammatory cells which produce variety of cytokines, chemokines and growth factors that may affect tumor behavior. One of the cytokines suggested to be involved in the pathogenesis of BCC is IL-6, which is the upstream element of IL-6/JAK/STAT3 pathway. The correlation between polymor...
Mieremet, Arnout Boiten, Walter van Dijk, Rianne Gooris, Gert Overkleeft, Herman S. Aerts, Johannes M. F. G. Bouwstra, Joke A. El Ghalbzouri, Abdoelwaheb
Published in
Archives of Dermatological Research
Relative humidity (RH) levels vary continuously in vivo, although during in vitro generation of three-dimensional human skin equivalents (HSEs) these remain high (90–95%) to prevent evaporation of the cell-culture medium. However, skin functionality is directly influenced by environmental RH. As the barrier formation in HSEs is different, there is ...
Ren, Ziyou Laumann, Anne E. Silverberg, Jonathan I.
Published in
Archives of Dermatological Research
Patients with dermatomyositis have multiple risk factors for serious and opportunistic infections, including immune dysregulation, long-term systemic corticosteroid treatment and comorbid health conditions. We sought to determine whether dermatomyositis is associated with increased odds and burden of systemic, opportunistic and antibiotic-resistant...
