Liao, Zhijun Song, Zhangqing Xu, Jie Ma, Zheng Bechthold, Andreas Yu, Xiaoping
Published in
Applied microbiology and biotechnology
The polyene macrolide rimocidin, produced by Streptomyces rimosus M527, was found to be highly effective against a broad range of fungal plant pathogens. Current understanding of the regulatory mechanism of rimocidin biosynthesis and morphological differentiation in S. rimosus M527 is limited. NsdA is considered a negative regulator involved in mor...
Zhu, Yanping Lu, Ting Zhang, Jing Zhang, Peipei Tao, Meifeng Pang, Xiuhua
Published in
Applied microbiology and biotechnology
Although the genome of the Streptomyces model strain S. coelicolor was sequenced nearly two decades ago, the function of many annotated genes has not been verified, including that of gene sco1979, which was predicted to encode a transcriptional regulator of the xenobiotic response element (XRE) family. In this study, we showed that SCO1979 represse...
Lv, Chenfei Shi, Tingting Zhu, Pengpeng Peng, Xing Cao, Shangshang Yan, Yan Ojha, Nishant Kumar Liao, Min Zhou, Jiyong
Published in
Applied microbiology and biotechnology
Infectious bronchitis virus (IBV) is a member of genus gamma-coronavirus in the family Coronaviridae, causing serious economic losses to the poultry industry. Reverse genetics is a common technique to study the biological characteristics of viruses. So far, there is no BAC reverse genetic system available for rescue of IBV infectious clone. In the ...
Chen, Haitao Li, Kefeng Cai, Yao Wang, Pingping Gong, Weimin Wu, Long-Fei Song, Tao
Published in
Applied microbiology and biotechnology
Light-oxygen-voltage (LOV) proteins are ubiquitous photoreceptors that can interact with other regulatory proteins and then mediate their activities, which results in cellular adaptation and subsequent physiological changes. Upon blue-light irradiation, a conserved cysteine (Cys) residue in LOV covalently binds to flavin to form a flavin-Cys adduct...
Dzurendova, Simona Zimmermann, Boris Tafintseva, Valeria Kohler, Achim Ekeberg, Dag Shapaval, Volha
Published in
Applied microbiology and biotechnology
Oleaginous filamentous fungi grown under the nitrogen limitation, accumulate high amounts of lipids in the form of triacylglycerides (TAGs) with fatty acid profiles similar to plant and fish oils. In this study, we investigate the effect of six phosphorus source concentrations combined with two types of nitrogen substrate (yeast extract and ammoniu...
Chen, Xi Liao, Binyou Cheng, Lei Peng, Xian Xu, Xin Li, Yuqing Hu, Tao Li, Jiyao Zhou, Xuedong Ren, Biao
...
Published in
Applied microbiology and biotechnology
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel β-coronavirus, is the main pathogenic agent of the rapidly spreading pneumonia called coronavirus disease 2019 (COVID-19). SARS-CoV-2 infects much more people, especially the elder population, around the world than other coronavirus, such as SARS-CoV and MERS-CoV, which is ch...
Habe, Hiroshi Sato, Yuya Kirimura, Kohtaro
Published in
Applied microbiology and biotechnology
Levulinic acid (LA) is an important chemical building block listed among the top 12 value-added chemicals by the United States Department of Energy, and can be obtained through the hydrolysis of lignocellulosic biomass. Using the same approach as in the catalytic production of LA from biomass, catalytic methods to upgrade LA to higher value chemica...
de Souza Valente, Cecília Rodiles, Ana Freire Marques, Maria Risoleta Merrifield, Daniel Lee
Published in
Applied microbiology and biotechnology
White spot syndrome virus (WSSV) is one of the most virulent pathogens afflicting shrimp farming. Understanding its influence on shrimp intestinal microbiota is paramount for the advancement of aquaculture, since gut dysbiosis can negatively impact shrimp development, physiology, and immunological response. Thereupon, the data presented herein asse...
Koonthongkaew, Jirasin Toyokawa, Yoichi Ohashi, Masataka Large, Christopher R L Dunham, Maitreya J Takagi, Hiroshi
Published in
Applied microbiology and biotechnology
In the yeast Saccharomyces cerevisiae, the mitochondrial branched-chain amino acid (BCAA) aminotransferase Bat1 plays an important role in the synthesis of BCAAs (valine, leucine, and isoleucine). Our upcoming study (Large et al. bioRχiv. 10.1101/2020.06.26.166157, Large et al. 2020) will show that the heterozygous tetraploid beer yeast strain, Wye...
Zhang, Biao Ren, Lili Zeng, Shuai Zhang, Siyang Xu, Dayong Zeng, Xin Li, Feng
Published in
Applied microbiology and biotechnology
Glycolysis and the pentose phosphate pathway (PPP) are two basic metabolic pathways that are simultaneously present in yeasts. As the main pathway in most species, the glycolysis provides ATP and NADH for cell metabolism while PPP, as a complementary pathway, supplies NADPH. In this study, the performance of Kluyveromyces marxianus using glycolysis...
