Xiong, Yifan Cao, Gaihua Chen, Xiaolong Yang, Jun Shi, Meimei Wang, Yu Nie, Fuping Huo, Danqun Hou, Changjun
Published in
Applied microbiology and biotechnology
The livestock industry has been deeply affected by African swine fever virus (ASFV) and Capripoxvirus (CaPV), which caused an enormous economic damage. It is emergent to develop a reliable detection method. Here, we developed a rapid, ultra-sensitive, and one-pot DNA detection method combining recombinase polymerase amplification (RPA) and CRISPR/C...
Zhang, Linlin Wang, Ran Xie, Zhengde
Published in
Applied microbiology and biotechnology
Epstein-Barr virus (EBV) is an oncogenic virus that is closely associated with several malignant and lymphoproliferative diseases. Studies have shown that the typical characteristic of EBV-associated diseases is aberrant methylation of viral DNA and the host genome. EBV gene methylation helps EBV escape from immune monitoring and persist in host ce...
Hengsbach, Jan-Niklas Sabel-Becker, Björn Ulber, Roland Holtmann, Dirk
Published in
Applied microbiology and biotechnology
The electrochemical process of microbial electrosynthesis (MES) is used to drive the metabolism of electroactive microorganisms for the production of valuable chemicals and fuels. MES combines the advantages of electrochemistry, engineering, and microbiology and offers alternative production processes based on renewable raw materials and regenerati...
Atmaram, Upare Abhay Roopan, Selvaraj Mohana
Published in
Applied microbiology and biotechnology
The 5-membered oxadiazole and thiadiazole scaffolds are the most privileged and well-known heterocycles, being a common and essential feature of a variety of natural products and medicinal agents. These scaffolds take up the center position and are the core structural components of numerous drugs that belong to different categories. These include a...
Lu, Zhilong Wu, Yanling Chen, Ying Chen, Xiaoling Wu, Renzhi Lu, Qi Chen, Dong Huang, Ribo
Published in
Applied microbiology and biotechnology
spt23 plays multiple roles in the thermal tolerance of budding yeast. spt23 regulates unsaturated lipid acid (ULA) content in the cell, which can then significantly affect cellular thermal tolerance. Being a Ty suppressor, spt23 can also interact with transposons (Tys) that are contributors to yeast's adaptive evolution. Nevertheless, few studies h...
Thapa Magar, Roniya Lee, Seung Yeup Kim, Hyo Jeong Lee, Seon-Woo
Published in
Applied microbiology and biotechnology
Bacteriophages (phages) have been proposed as promising alternative pesticides against various bacterial diseases of crops. However, the efficacy of phages in managing plant bacterial diseases is variable and poorly understood in natural settings. In this study, two lytic phages, RpT1 and RpY2, were investigated for their biocontrol potential again...
Hesami, Mohsen Alizadeh, Milad Jones, Andrew Maxwell Phineas Torkamaneh, Davoud
Published in
Applied microbiology and biotechnology
Sequencing technologies are evolving at a rapid pace, enabling the generation of massive amounts of data in multiple dimensions (e.g., genomics, epigenomics, transcriptomic, metabolomics, proteomics, and single-cell omics) in plants. To provide comprehensive insights into the complexity of plant biological systems, it is important to integrate diff...
Situmorang, Magdalena Lenny Uawisetwathana, Umaporn Arayamethakorn, Sopacha Karoonuthaisiri, Nitsara Rungrassamee, Wanilada Haniswita, Haniswita Bossier, Peter Suantika, Gede
Published in
Applied microbiology and biotechnology
The emergence of Vibrio diseases, including acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio spp., had resulted in heavy losses in global shrimp production. Biofloc technology is a closed aquaculture system developed as one of the sustainable solutions to increase system resilience in the shrimp industry. In this study, biofloc was ...
Johny, Tina Kollannoor Puthusseri, Rinu Madhu Saidumohamed, Bindiya Ellathuparambil Sheela, Unnikrishnan Babukuttan Puthusseri, Saipriya Parol Sasidharan, Raghul Subin Bhat, Sarita Ganapathy
Published in
Applied microbiology and biotechnology
L-asparaginase catalyzes the hydrolysis of L-asparagine to L-aspartic acid and ammonia. It has application in the treatment of acute lymphoblastic leukemia in children, as well as in other malignancies, in addition to its role as a food processing aid for the mitigation of acrylamide formation in the baking industry. Its use in cancer chemotherapy ...
Nutakor, Christabel Kanwugu, Osman N Kovaleva, Elena G Glukhareva, Tatiana V
Published in
Applied microbiology and biotechnology
Astaxanthin is an important ketocarotenoid with remarkable biological activities and high economic value. In recent times, natural astaxanthin production by microorganisms has attracted much attention particularly in pharmaceuticals, nutraceuticals, cosmetics, and food and feed industries. Though, currently, productivity is still low and has restri...
