Froidurot, Alicia Jacotot, Emmanuel Julliand, Samy Grimm, Pauline Julliand, Véronique
Published in
Applied and Environmental Microbiology
Cellulose is the most abundant of plant cell wall fiber and can only be degraded by the large intestine microbiota, resulting in the production of volatile fatty acids that are essential for the host nutrition and health. Consequently, cellulolytic bacteria are of major importance to herbivores. However, these bacteria are challenged by various fac...
McKinnon Reish, Hannah Dewey, Lindsey Kirschman, Lucas J.
Published in
Applied and Environmental Microbiology
Pseudoreplication compromises the validity of research by treating non-independent samples as independent replicates. This review examines the prevalence of pseudoreplication in host–microbiota studies, highlighting the critical need for rigorous experimental design and appropriate statistical analysis. We systematically reviewed 115 manuscripts on...
Fu, Yezhi Nawrocki, Erin M. M’ikanatha, Nkuchia M. Dudley, Edward G.
Published in
Applied and Environmental Microbiology
Enterotoxigenic Escherichia coli (ETEC)-associated diarrhea represent one of the most economically important diseases in the livestock industry. By analyzing over a thousand livestock-derived ETEC samples in the United States, our study unveiled a clear distinction in ETEC’s genetic traits (i.e., genotypes, antimicrobial resistance [AMR], and virul...
Jansen, Zachary Alameri, Abdulaziz Wei, Qiyao Kulhanek, Devon L. Gilmour, Andrew R. Halper, Sean Schwalm, Nathan D. III Thyer, Ross
Published in
Applied and Environmental Microbiology
Soil-dwelling Actinomycetes, particularly the Mycobacteriales, include both diverse new hosts for sustainable biomanufacturing and emerging opportunistic pathogens. Rhodococcus, Gordonia, and Nocardia are three abundant genera with particularly flexible metabolisms and untapped potential for natural product discovery. Among these, Rhodococcus ruber...
Kanno, Kosuke Kuriki, Riko Yasuno, Yoko Shinada, Tetsuro Ito, Tomokazu Hemmi, Hisashi
Published in
Applied and Environmental Microbiology
The recent discovery of various modified mevalonate pathways in microorganisms, such as archaea and Chloroflexota bacteria, has shed light on the complexity of the evolution of metabolic pathways, including those involved in primary metabolism. The fact that the archaeal mevalonate pathway, which is almost exclusive to the domain Archaea, exists in...
Hung, Jia-He Zhang, Shi-Min Huang, Shir-Ly
Published in
Applied and Environmental Microbiology
Nitrate is a pivotal ecological factor influencing microbial community and metabolism. Dietary nitrate provides health benefits including anti-diabetic and anti-hypertensive effects via microbial-derived metabolites such as nitrite. Unraveling the impacts of nitrate on the growth and metabolism of human commensal bacteria is imperative to comprehen...
Asakawa, Mikari Kageyama, Shinya Said, Heba Shehta Ma, Jiale Suma, Shino Furuta, Michiko Takeshita, Toru
Published in
Applied and Environmental Microbiology
The interaction between fungal and bacterial components involved in the virulence of oral microbiota has received attention. This study demonstrates that an increase in fungal components is associated with a dysbiotic bacterial community and poor health status in elderly adults. Among individuals with a high-density fungal population, particularly,...
Li, Siqi Zhang, Weiping
Published in
Applied and Environmental Microbiology
Shigella is a leading cause of diarrhea in children younger than 5 years in developing countries (children’s diarrhea) and continues to be a major threat to public health. No licensed vaccines are currently available against the heterogeneous Shigella species and serotype strains. Aiming to develop a cross-protective multivalent vaccine against shi...
Hou, Shuo Gao, Cong Liu, Jia Chen, Xiulai Wei, Wanqing Song, Wei Hu, Guipeng Li, Xiaomin Wu, Jing Liu, Liming
...
Published in
Applied and Environmental Microbiology
Hyperosmotic stress tolerance in the host strain is a significant challenge for fermentation performance in industrial production. In this study, we showed that the S. cerevisiae mediator Med3 is essential for yeast growth under hyperosmotic conditions. Med3 interacts with the transcription factor Stb5 to regulate the expression of genes involved i...
Bonné, Robin Marshall, Ian P. G. Bjerg, Jesper J. Marzocchi, Ugo Manca, Jean Nielsen, Lars Peter Aiyer, Kartik
Published in
Applied and Environmental Microbiology
Extracellular electron transfer is a metabolic function associated with electroactive bacteria wherein electrons are exchanged with external electron acceptors or donors. This feature has enabled the development of several applications, such as biosensing, carbon capture, and energy recovery. Cable bacteria are a unique class of long, filamentous m...
