Riccò, Matteo Baldassarre, Antonio Corrado, Silvia Bottazzoli, Marco Marchesi, Federico
Published in
Tropical medicine and infectious disease
Crimean Congo Hemorrhagic Fever (CCHF) Virus can cause a serious human disease, with the case fatality ratio previously estimated to be 30-40%. Our study summarized seroprevalence data from occupational settings, focusing on the following occupational groups: animal handlers, abattoir workers, farmers, healthcare workers, veterinarians, rangers, an...
Lin, Chien-Teng Lin, Chuen-Fu Wu, Jui-Te Tsai, Hsiao-Pei Cheng, Shu-Ying Liao, Huei-Jyuan Lin, Tzu-Chun Wu, Chao-Hsuan Lin, Yu-Chin Wang, Jiann-Hsiung
...
Published in
Animals : an open access journal from MDPI
The pharmacological pathway of para-toluenesulfonamide (PTS) restricts the kinase activity of the mammalian target of rapamycin, potentially leading to reductions in cell division, cell growth, cell proliferation, and inflammation. These pathways have a critical effect on tumorigenesis. We aimed to examine the antitumor effect of PTS or PTS combine...
Jain, Pankaj K Sharma, Neeraj Saba, Luca Paraskevas, Kosmas I Kalra, Mandeep K Johri, Amer Laird, John R Nicolaides, Andrew N Suri, Jasjit S
Published in
Diagnostics (Basel, Switzerland)
The early detection of carotid wall plaque is recommended in the prevention of cardiovascular disease (CVD) in moderate-risk patients. Previous techniques for B-mode carotid atherosclerotic wall plaque segmentation used artificial intelligence (AI) methods on monoethnic databases, where training and testing are from the "same" ethnic group ("Seen A...
Thapa, Pratik Jiang, Hong Ding, Na Hao, Yanning Alshahrani, Aziza Lee, Eun Y Fujii, Junichi Wei, Qiou
Published in
Antioxidants (Basel, Switzerland)
Peroxiredoxin IV (Prx4), a typical two-cysteine-containing member of the peroxidase family, functions as an antioxidant to maintain cellular redox homeostasis through the reduction of reactive oxygen species (ROS) via cycles of oxidation-reduction reactions. Under oxidative stress, all Prxs including Prx4 are inactivated as their catalytic cysteine...
Woodbury, R. Brian Beans, Julie A. Wark, Kyle A. Spicer, Paul Hiratsuka, Vanessa Y.
Published in
Frontiers in Communication
Background: Precision medicine seeks to better tailor medical care to the needs of individual patients, but there are challenges involved in communicating to patients, health care providers, and health system leaders about this novel and complex approach to research and clinical care. These challenges may be exacerbated for Alaska Native and Americ...
van der Werf, Niels R van Gent, Margo Booij, Ronald Bos, Daniel van der Lugt, Aad Budde, Ricardo P J Greuter, Marcel J W van Straten, Marcel
Published in
Diagnostics (Basel, Switzerland)
In order to assess coronary artery calcium (CAC) quantification reproducibility for photon-counting computed tomography (PCCT) at reduced tube potential, an anthropomorphic thorax phantom with low-, medium-, and high-density CAC inserts was scanned with PCCT (NAEOTOM Alpha, Siemens Healthineers) at two heart rates: 0 and 60-75 beats per minute (bpm...
anastassova;, neda
In light of the known neuroprotective properties of indole compounds and the promising potential of hydrazone derivatives, two series of aldehyde-heterocyclic hybrids combining those pharmacophores were synthesized as new multifunctional neuroprotectors. The obtained derivatives of indole-3-propionic acid (IPA) and 5-methoxy-indole carboxylic acid ...
jesús, maría
Obesity is a global health issue, in which modifications in gut microbiota composition have a key role. Different therapeutic strategies are being developed in combination with diet and exercise, including the use of plant extracts, such as those obtained from Morus alba L. leaves. Recent studies have revealed their anti-inflammatory and antioxidan...
h., lauren
Oxidative stress is a major hallmark of COPD, contributing to inflammatory signaling, corticosteroid resistance, DNA damage, and accelerated lung aging and cellular senescence. Evidence suggests that oxidative damage is not solely due to exogenous exposure to inhaled irritants, but also endogenous sources of oxidants in the form of reactive oxygen ...
de simone;, giuseppe
Schizophrenia is a worldwide mental illness characterized by alterations at dopaminergic and glutamatergic synapses resulting in global dysconnectivity within and between brain networks. Impairments in inflammatory processes, mitochondrial functions, energy expenditure, and oxidative stress have been extensively associated with schizophrenia pathop...
