Can the sampling method affect the detection of incidental gallbladder carcinoma? Comparative analysis of two sampling m...
Published in Annals of diagnostic pathology
Diagnostic utility of combining PRAME and HMB-45 stains in primary melanocytic tumors.
Published in Annals of diagnostic pathology
Pathologists face ongoing challenges distinguishing between benign and malignant melanocytic tumors. PRAME (PReferentially expressed Antigen in Melanoma) has a demonstrated value distinguishing between these types of lesions. However, the sensitivity of single immunohistochemistry is variable. HMB-45 is another valuable marker, but on its own, has ...
From the archives of MD Anderson Cancer Center: Plasmablastic lymphoma presenting as a kidney mass in an immunocompetent...
Published in Annals of diagnostic pathology
Plasmablastic lymphoma (PBL) is a rare, aggressive large B-cell lymphoma with plasmablastic or immunoblastic morphology and a terminally differentiated B-cell immunophenotype. PBL often presents at extranodal sites, commonly the oral cavity of immunocompromised patients with human immunodeficiency virus (HIV) and/or Epstein-Barr virus (EBV) infecti...
Histology and clinical correlations in autoimmune hepatitis, primary biliary cholangitis, and autoimmune hepatitis-prima...
Published in Annals of diagnostic pathology
The diagnosis of autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and AIH-PBC overlap syndrome (OS) relies on their histologic features and clinical findings. In this study, we aimed to identify specific morphologic features of these diseases and evaluate their clinical correlation. We included initial biopsies from untreated patients...
Ampulla of Vater biopsies: A retrospective 10-year, single-institution study.
Published in Annals of diagnostic pathology
Endoscopic biopsies from the ampulla of Vater are challenging due to specimen sampling limitation, small size, interventional artifacts, and the nature of local complex anatomy. We retrospectively reviewed 318 in-house ampulla of Vater biopsy specimens from 252 patients over a 10-year period. The biopsy findings were compared to those in subsequent...
Ganglion cyst of temporomandibular joint - A systematic review.
Published in Annals of diagnostic pathology
Ganglion cyst of the temporomandibular joint (TMJ) is an uncommon pathology with uncertain etiology. There is no consensus on their management. The current systematic review aimed to discuss the clinical and histopathological features of ganglion cysts of TMJ, to aid in appropriate treatment. A literature search was done and a total of 20 cases wer...
A case-control autopsy series of liver pathology associated with novel coronavirus disease (COVID-19).
...Published in Annals of diagnostic pathology
Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for coronavirus disease 2019 (COVID-19) is most well-known for causing pulmonary injury, a significant proportion of patients experience hepatic dysfunction. The mechanism by which SARS-CoV2 causes liver injury is not fully understood. The goal of this study was to de...
Comparative expression of trophoblast cell-surface antigen 2 (TROP2) in the different molecular subtypes of invasive bre...
Published in Annals of diagnostic pathology
Sacituzumab govitecan, targeting trophoblast cell-surface antigen 2 (TROP2), is approved for the treatment of triple-negative and hormone receptor-positive/HER2-negative breast cancers. However, detailed studies comparing TROP2 protein expression in the different molecular subtypes of breast cancer are limited, and definitive evidence supporting th...
Editorial: Juan Rosai, M.D. (1940-2020).
Published in Annals of diagnostic pathology
Distinct histological and clinical features associated with pure uterine serous carcinoma: A single institution experien...
Published in Annals of diagnostic pathology
To ascertain the clinicopathological features, survival, and prognostic factors of pure uterine serous carcinoma (pUSC) and compare its clinicopathological characteristics with those of serous-like grade-3 endometrioid endometrial carcinoma (G3-EEC). Consecutive patients with pUSC and p53 abnormal (p53abn) G3-EEC were retrospectively selected betwe...
