Claustre, Johanna Larcher, Romaric Jouve, Thomas Truche, Anne-Sophie Nseir, Saad Cadiet, Julien Zerbib, Yoann Lautrette, Alexandre Constantin, Jean-Michel Charles, Pierre-Emmanuel
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Published in
Annals of Intensive Care
BackgroundMucormycosis is an invasive fungal infection, with an increasing incidence especially in patients with hematological malignancies. Its prognosis is poor because of its high invasive power and its intrinsic low susceptibility to antifungal agents. We aimed to describe the epidemiology of mucormycosis in intensive care units (ICU) and evalu...
Candela, Nelly Silva, Stein Georges, Bernard Cartery, Claire Robert, Thomas Moussi-Frances, Julie Rondeau, Eric Rebibou, Jean-Michel Lavayssiere, Laurence Belliere, Julie
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Published in
Annals of Intensive Care
BackgroundRhabdomyolysis is a life-threatening disease that can lead to severe hyperkalemia, acute kidney injury (AKI) and hypovolemic shock. The predictive factors of AKI and acute to chronic kidney disease (CKD) transition remain poorly described.MethodsThis multicenter retrospective study enrolled 387 patients with severe rhabdomyolysis (CPK > 5...
Lasocki, Sigismond Pène, Frédéric Ait-Oufella, Hafid Aubron, Cécile Ausset, Sylvain Buffet, Pierre Huet, Olivier Launey, Yoann Legrand, Matthieu Lescot, Thomas
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Published in
Annals of Intensive Care
ObjectiveAnemia is very common in critical care patients, on admission (affecting about two-thirds of patients), but also during and after their stay, due to repeated blood loss, the effects of inflammation on erythropoiesis, a decreased red blood cell life span, and haemodilution. Anemia is associated with severity of illness and length of stay.Me...
Bigé, Naïke Lavillegrand, Jean-Rémi Dang, Julien Attias, Philippe Deryckere, Stéphanie Joffre, Jérémie Dubée, Vincent Preda, Gabriel Dumas, Guillaume Hariri, Geoffroy
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Published in
Annals of Intensive Care
BackgroundDespite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, predictive factors of IHI remain poorly explored. The objective of this study was to evaluate the relationship between baseline mac...
Franchineau, Guillaume Bréchot, Nicolas Hekimian, Guillaume Lebreton, Guillaume Bourcier, Simon Demondion, Pierre Le Guennec, Loïc Nieszkowska, Ania Luyt, Charles-Edouard Combes, Alain
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Published in
Annals of Intensive Care
BackgroundProne positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of PP on global and regional ventilation, and optimal PEEP level.MethodsA monocentric study conducted on ECMO-supported s...
Tissières, Pierre Teboul, Jean-Louis
Published in
Annals of Intensive Care
Recent paediatric cases of acute myocarditis following a SARS-CoV-2 infection have raised the possibility of post-infective complications of COVID-19. This short editorial is reviewing current understanding of this new complication, its pathophysiology, diagnosis and therapeutic strategy.
Fuhrmann, Valentin Weber, Theresa Roedl, Kevin Motaabbed, Jasmin Tariparast, Adel Jarczak, Dominik de Garibay, Aritz Perez Ruiz Kluwe, Johannes Boenisch, Olaf Herkner, Harald
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Published in
Annals of Intensive Care
BackgroundPrevalence of multiple organ failure (MOF) in critically ill patients is increasing and associated mortality remains high. Extracorporeal organ support is a cornerstone in the management of MOF. We report data of an advanced hemodialysis system based on albumin dialysis (ADVOS multi device) that can regulate acid–base balance in addition ...
Diehl, J.-L. Peron, N. Chocron, R. Debuc, B. Guerot, E. Hauw-Berlemont, C. Hermann, B. Augy, J. L. Younan, R. Novara, A.
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Published in
Annals of Intensive Care
RationaleCOVID-19 ARDS could differ from typical forms of the syndrome.ObjectivePulmonary microvascular injury and thrombosis are increasingly reported as constitutive features of COVID-19 respiratory failure. Our aim was to study pulmonary mechanics and gas exchanges in COVID-2019 ARDS patients studied early after initiating protective invasive me...
De Pascale, Gennaro Lisi, Lucia Ciotti, Gabriella Maria Pia Vallecoccia, Maria Sole Cutuli, Salvatore Lucio Cascarano, Laura Gelormini, Camilla Bello, Giuseppe Montini, Luca Carelli, Simone
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Published in
Annals of Intensive Care
BackgroundIn critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe the pharmacokinetic/pharmacodynamic (PK/PD) profile of HD TGC in a cohort of critically ill patient...
Honore, Patrick M. Spapen, Herbert D. Marik, Paul Boer, Willem Oudemans-van Straaten, Heleen
Published in
Annals of Intensive Care
