How Social Distancing Brought Us Closer as a BME Community
Published in Annals of Biomedical Engineering
Subject-Specific Finite Element Modelling of the Human Hand Complex: Muscle-Driven Simulations and Experimental Validati...
Published in Annals of Biomedical Engineering
This paper aims to develop and validate a subject-specific framework for modelling the human hand. This was achieved by combining medical image-based finite element modelling, individualized muscle force and kinematic measurements. Firstly, a subject-specific human hand finite element (FE) model was developed. The geometries of the phalanges, carpa...
Analysis of Gender Perceptions in Health Technology: A Call to Action
Published in Annals of Biomedical Engineering
Gender diversity has been linked to positive business results. Yet limited data exist to characterize the gender landscape in health technology, a field that draws employees from both biomedical engineering and medicine. To better understand the state of gender diversity in this industry, we developed a survey to explore leadership representation a...
Quantifying Soft Tissue Artefacts and Imaging Variability in Motion Capture of the Fingers
...Published in Annals of Biomedical Engineering
This study assessed the accuracy of marker-based kinematic analysis of the fingers, considering soft tissue artefacts (STA) and marker imaging uncertainty. We collected CT images of the hand from healthy volunteers with fingers in full extension, mid- and full-flexion, including motion capture markers. Bones and markers were segmented and meshed. T...
Fluid–Structure Interaction Models of Bioprosthetic Heart Valve Dynamics in an Experimental Pulse Duplicator
Published in Annals of Biomedical Engineering
Computer modeling and simulation is a powerful tool for assessing the performance of medical devices such as bioprosthetic heart valves (BHVs) that promises to accelerate device design and regulation. This study describes work to develop dynamic computer models of BHVs in the aortic test section of an experimental pulse-duplicator platform that is ...
Dynamics of Cell Death After Conventional IRE and H-FIRE Treatments
Published in Annals of Biomedical Engineering
High-frequency irreversible electroporation (H-FIRE) has emerged as an alternative to conventional irreversible electroporation (IRE) to overcome the issues associated with neuromuscular electrical stimulation that appear in IRE treatments. In H-FIRE, the monopolar pulses typically used in IRE are replaced with bursts of short bipolar pulses. Curre...
Quantifying Subresolution 3D Morphology of Bone with Clinical Computed Tomography.
...Published in Annals of biomedical engineering
The aim of this study was to quantify sub-resolution trabecular bone morphometrics, which are also related to osteoarthritis (OA), from clinical resolution cone beam computed tomography (CBCT). Samples (n = 53) were harvested from human tibiae (N = 4) and femora (N = 7). Grey-level co-occurrence matrix (GLCM) texture and histogram-based parameters ...
Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation.
Published in Annals of biomedical engineering
Early degenerative changes of articular cartilage are detected using contrast-enhanced computed tomography (CT) with a cationic contrast agent (CA). However, cationic CA diffusion into degenerated cartilage decreases with proteoglycan depletion and increases with elevated water content, thus hampering tissue evaluation at early diffusion time point...
The Capacity of Generic Musculoskeletal Simulations to Predict Knee Joint Loading Using the CAMS-Knee Datasets
Published in Annals of Biomedical Engineering
Musculoskeletal models enable non-invasive estimation of knee contact forces (KCFs) during functional movements. However, the redundant nature of the musculoskeletal system and uncertainty in model parameters necessitates that model predictions are critically evaluated. This study compared KCF and muscle activation patterns predicted using a scaled...
Correction to: An Integrated In Vitro – In Silico Approach for Silver Nanoparticle Dosimetry in Cell Cultures
Published in Annals of Biomedical Engineering
