Published in Annales pharmaceutiques francaises
To avoid frequent drug administration, PLGA-based monolithic filament-shaped implants were prepared. In this study, the effect of different formulation variables was studied, namely: type of PLGA (PLGA 502 and PLGA 503), type of drug (the lipophilic Prednisolone acetate, PA and the hydrophilic Propranolol Hydrochloride, PH) and drug loading (10 and...
Published in Annales pharmaceutiques francaises
Action should be taken to decide on the use of filter needles including studies to confirm the consequences of the presence of these particles on an animal model, discussions with regulatory authorities to clarify the situation, incentives for manufacturers to use vials.
Published in Annales pharmaceutiques francaises
The stability of the rituximab biosimilar CT-P10, in 50mL vials at a concentration of 10mg/mL, and after dilution to final concentrations of 1 and 4mg/mL and storage in polyolefin bags at 4°C and 25°C was studied by several orthogonal and complementary methods. No significant change (as defined by a magnitude greater than the inter-batch variabilit...
Published in Annales pharmaceutiques francaises
Malva nut polysaccharide has potential as a key ingredient in skin hydrating products, which should encourage its further development.
Published in Annales pharmaceutiques francaises
Now, the pharmaceutical record is systematically used in the hospital drugs sales service, and its content is systematically analyzed. It represents one of the tool improving communication between town-hospital networks, and helps secure the ambulatory drugs dispensation.
Published in Annales pharmaceutiques francaises
This work describes five simple and reliable spectrophotometric and chromatographic methods for analysis of hepatitis C antiviral binary mixture of ledipasvir (LPV) and sofosbuvir (SBV). Method I is based on the use of Amax and derivative spectrophotometry with the zero-crossing technique where LPV was determined using its Amax and 1D amplitudes at...
Published in Annales pharmaceutiques francaises
A good training of health professionals in using economic and statistic tools, and the transferability of results of medico-economic studies are essential and should be optimized to enable a broader use of medico-economic evaluation within the scope of decision-making in French hospitals.
Published in Annales pharmaceutiques francaises
Despite recommendations and information about the terms of stops, some clinical situations result in withdrawal symptoms, a patient died in our study, death appears in connection with the withdrawal situation. Note that the human factor is the main factor related to the circumstances of occurrence of withdrawal.
Published in Annales pharmaceutiques francaises
e-Health offers perspectives for patients, healthcare professionals and healthcare system, although this concept appears difficult to appreciate and to define. Uncertainties remain on the efficiency of these tools and their safety in particular with respect to personal data of the patients. Thus, we can observe the emergence of new categories of li...
Published in Annales pharmaceutiques francaises
The results suggested a potent antioxidant activity of M. vulgare flavonoids extracts, which may find its application in feature research for the food and the pharmacological industries.
