Mullangi, S Ravindhranath, K Yarala, M R Panchakarla, R K
Published in
Annales pharmaceutiques francaises
A highly sensitive LC-MS/MS method for the trace level determination of genotoxic impurities, Cinnamyl chloride and Benzhydryl chloride, in Cinnarizine drug substance was developed and validated. Chromatographic separation was successfully achieved on Atlantis d C18 column with dimensions 150× 4.6mm and particle size: 5μm. 0.1% Trifluoroacetic acid...
Vengadessane, Subashini Viglietti, Denis Sauvageon, Hélène Glotz, Denis Lefaucheur, Carmen Madelaine, Isabelle Deville, Laure
Published in
Annales pharmaceutiques francaises
The aims of this study were to assess medication adherence to immunosuppressive treatment in kidney transplanted patients, to identify predictive factors of medication non-adherence and to analyse its impact on the development of Donor Specific Antibodies (DSA) de novo, biomarkers of rejection in transplant recipients. A cross-sectional single-cent...
Drillon, P Desvergée, A Prevost, V Blaizot, X
Published in
Annales pharmaceutiques francaises
Hormone therapy provides an excellent survival rate after cancer but has many side effects, including joint pain in one out of two women. This leads about 13 % of women to stop their treatment within the first 6 months, impacting on its effectiveness, survival and the risk of recurrence. In order to better manage pain and quality of life, physical ...
Vacheron, C-H Piriou, V Untereiner, O Picard, J Thiveaud, D Theissen, A
Published in
Annales pharmaceutiques francaises
Wrong route medication errors due to tubing misconnections can lead to serious adverse events, especially when they concern the neuraxial and perineural routes. It has been favoured by the use of the universal Luer connector for medical devices with a risk of confusion with the intravenous route. The prevention of these errors is based on passive m...
Renet, S Chaumais, M-C Gallant-Dewavrin, M Jouet, E Bezie, Y Humbert, M Rieutord, A Las Vergnas, O
Published in
Annales pharmaceutiques francaises
To better understand the role of pharmacists in patient education and counselling: describe the perception of knowledge exchange (KE) between asthma/pulmonary arterial hypertension patients and pharmacists (hospital/community) according to four dimensions (4C-typology): cure (C1), care (C2); coordination/supply chain (C3), characteristics of the pa...
Poggio, S Roy, S Bégué, T Dumenil, A-S Henry, C
Published in
Annales pharmaceutiques francaises
In orthopedic surgery, the well-known iatrogenic risk of oral anticoagulants is particularly increased due to surgical management (suspension and resumption of treatment). In order to prevent avoidable iatrogenic events linked to incomplete discharge documents, targeted medical reconciliation (MR) has been deployed. This is a single-center prospect...
Barbier, A Rousselière, C Robert, L Cousein, E Décaudin, B
Published in
Annales pharmaceutiques francaises
Develop a methodological guide on the implementation of a PDSS (pharmaceutical decision support system). Observational study, retrospective conducted at Lille University Hospital from May 2017 to December 2020, corresponding to the period of implementation and then use of the software. The different phases of the project are described as well as th...
Bhupatiraju, Rajesh Varma Battula, Sreenivasa Rao Kapavarapu, Maruthi Venkata Narayana Rao... Mandapati, Varaprasad Reddy
Published in
Annales pharmaceutiques francaises
A simple and robust head space/gas chromatography with flame ionisation sensor (HS/GC/FIS) approach for the trace evaluation of carcinogenic impurity, methyl chloride, in trimetazidine dihydrochloride (TRD) drug ingredient and its formulation is described. This HS/GC/FIS approach was based on separation and analysis of CH3Cl content on DB-624 [75.0...
Blin, M Cherel, A Bouglé, C Piriou, G
Published in
Annales pharmaceutiques francaises
The implementation of pharmaceutical monitoring as defined by the Council of Europe in its Resolution of March 2020 requires defining for each patient, objectives and a treatment plan, to share, monitor and update them in a manner coordinated, interprofessional and in partnership with the patient. It recognizes the central place of the pharmacist b...
Richet, E Ferret, L Gaboriau, L Charpentier, P Dujardin, L Fulcrand, J Boursier, A
Published in
Annales pharmaceutiques francaises
Dronabinol is a drug composed of synthetic delta-9-tetrahydrocannabinol. In France, dronabinol requires a named Temporary Utilisation Authorisation (TUA), for the treatment of refractory neuropathic pain. Few data currently exist concerning its efficacy and tolerance. We present our feedback on its use for chronic pain patients, the multidisciplina...