Ghosh, Arghya Biju, Akkattu T
Published in
Angewandte Chemie (International ed. in English)
The secondary amine-catalyzed reactions proceeding via α,β-unsaturated iminiums and the N-heterocyclic carbene (NHC)-catalyzed transformations taking place via α,β-unsaturated acylazoliums are the two widely used electrophilic intermediates in organocatalysis. Over the last two decades, these two intermediates are extensively utilized for the enant...
Jin, Rongchao Tang, Li Ma, Along Zhang, Cheng Liu, Xuguang Wang, Shuxin
Published in
Angewandte Chemie (International ed. in English)
Bimetallic coreshell nanostructures hold great promise in elucidating the bimetallic synergism. However, it remains a challenge to construct atomically precise core-shell with high-valence active metals on the gold surface. In this work, we report the total structure of a [Au42Cd40(SR)52]2- coreshell nanocluster and multiple implications. Single cr...
Kajetanowicz, Anna Grela, Karol
Published in
Angewandte Chemie (International ed. in English)
Advanced applications of the Nobel Prize winning olefin metathesis reaction require user-friendly and highly universal catalysts. From many successful metathesis catalysts, which belong to the two distinct classes of Schrock and Grubbs-type catalysts, the subclass of chelating-benzylidene ruthenium complexes (so-called Hoveyda-Grubbs catalysts) add...
Badjic, Jovica D Pavlović, Radoslav Z Lalisse, Remy F Hansen, Alexandar L Waudby, Christopher A Zhiquan, Lei Guney, Murat Wang, Xiuze Hadad, Christopher M
Published in
Angewandte Chemie (International ed. in English)
Two limiting cases of molecular recognition, induced fit (IF) and conformational selection (CS), play a central role in allosteric regulation of natural systems. The IF paradigm states that a substrate "instructs" the host to change its shape after complexation, while CS asserts that a guest "selects" the optimal fit from an ensemble of preexisting...
Xu, Lujuan Kuan, Seah Ling Weil, Tanja
Published in
Angewandte Chemie (International ed. in English)
Site-selective protein functionalization serves as an invaluable tool for investigating protein structures and functions in complicated cellular environments and accomplishing semi-synthetic protein conjugates such as traceable therapeutics with improved features. Dual functionalization of proteins allows the incorporation of two different types of...
Wemyss, Alan M Ellingford, Christopher Morishita, Yoshihiro Bowen, Chris Wan, Chaoying
Published in
Angewandte Chemie (International ed. in English)
While the fascinating field of soft machines has grown rapidly over the last two decades, the materials they are constructed from have remained largely unchanged during this time. Parallel activities have led to significant advances in the field of dynamic polymer networks, leading to the design of three-dimensionally cross-linked polymeric materia...
Li, Jingchao Luo, Yu Pu, Kanyi
Published in
Angewandte Chemie (International ed. in English)
Immunotherapy that harnesses the power of the immune system to eliminate malignant cells has offered an effective approach for cancer treatment. However, limited patient response rates and potential immune-related adverse events exist as two major issues for cancer immunotherapy. In parallel, a variety of electromagnetic nanomaterials that generate...
Houk, Kendall N Liu, Fang Yang, Zhongyue Seeman, Jeffrey I
Published in
Angewandte Chemie (International ed. in English)
This review article describes the evolution of Woodward's mechanistic thinking, beginning in the late 1930s and early 1940s with his proposal of a charge-transfer mechanism for the Diels-Alder reaction, eventually leading to the Woodward-Katz two-stage concerted mechanism in 1959, and then to its mechanistic solution in terms of orbital symmetry co...
Ma, Jizhen Liu, Miaomiao He, Yulong Zhang, Jintao
Published in
Angewandte Chemie (International ed. in English)
Halogens have been coupled with metal anodes in a single cell to develop novel rechargeable batteries based on extrinsic redox reactions. Since the commercial introduction of lithium-iodine batteries in 1972, they have shown great potential to match the high-rate performance, large energy density, and good safety of advanced batteries. With the dev...
Nobile, Enzo Castanheiro, Thomas Besset, Tatiana
Published in
Angewandte Chemie (International ed. in English)
Due to their unique properties, fluorinated scaffolds are pivotal compounds in pharmaceuticals, agrochemicals, and materials science. Over the last years, the development of versatile strategies for the selective synthesis of fluorinated molecules by direct C-H bond functionalization has attracted a lot of attention. In particular, the design of no...
