Abandoning inhalational anaesthesia.
Published in Anaesthesia
The association of allogeneic blood transfusion and the recurrence of hepatic cancer after surgical resection.
Published in Anaesthesia
There is conflicting evidence whether allogeneic blood transfusion influences survival or cancer recurrence after resection of hepatocellular cancer. We followed up 1469 patients who had undergone hepatocellular resection for a median (IQR [range]) of 45 (21-78 [0-162]) months, of whom 626 (43%) had had blood transfusion within 7 days of surgery. B...
Future directions in regional anaesthesia: not just for the cognoscenti.
Published in Anaesthesia
Hypoxic ventilatory response after rocuronium-induced partial neuromuscular blockade in men with obstructive sleep apnoe...
Published in Anaesthesia
Obstructive sleep apnoea and residual neuromuscular blockade are, independently, known to be risk factors for respiratory complications after major surgery. Residual effects of neuromuscular blocking agents are known to reduce the hypoxic ventilatory response in healthy volunteers. Patients with obstructive sleep apnoea have impaired control of bre...
Supplemental peri-operative intravenous crystalloids for postoperative nausea and vomiting: an abridged Cochrane systema...
Published in Anaesthesia
We conducted a Cochrane systematic review on the effectiveness of supplemental intravenous crystalloid administration in preventing postoperative nausea and vomiting. We included randomised controlled trials of patients undergoing surgery under general anaesthesia and given supplemental peri-operative intravenous crystalloid. Our primary outcomes w...
Dynamic predictive model for postoperative nausea and vomiting for intravenous fentanyl patient-controlled analgesia.
Published in Anaesthesia
Postoperative nausea and vomiting is the most common side-effect of opioid-based intravenous patient-controlled analgesia. Apfel's simplified risk score is popular but it has some limitations. We developed and validated a dynamic predictive model for nausea or vomiting up to 48 postoperative hours, available as an online web application. Fentanyl w...
Improving early warning scores - more data, better validation, the same response.
Published in Anaesthesia
Feasibility and pilot studies: dropping the fig leaf.
Published in Anaesthesia
Lung ultrasound for early diagnosis of postoperative need for ventilatory support: a prospective observational study.
Published in Anaesthesia
Pulmonary complications have a significant impact on morbidity and mortality in patients after major surgery. Lung ultrasound can be used at the bed-side, and has gained widespread acceptance in the intensive care unit. We conducted a prospective study to evaluate whether lung ultrasound could be used as a predictive marker for postoperative ventil...
Pre-hospital advanced airway management: does early tracheal intubation decrease the mortality rate? A reply.
Published in Anaesthesia
