Bain, William Li, Huihua van der Geest, Rick Moore, Sara R Olonisakin, Tolani F Ahn, Brian Papke, Erin Moghbeli, Kaveh DeSensi, Rebecca Rapport, Sarah
...
Published in
American journal of respiratory and critical care medicine
Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which can amplify all complement activity, during critical illness. We examined the function and key components of the alternative complement pathway in a series of critically-ill patients and in a ...
Huang, Yongbo Chen, Sibei Yang, Zifeng Guan, Wenda Liu, Dongdong Lin, Zhimin Zhang, Yu Xu, Zhiheng Liu, Xiaoqing Li, Yimin
...
Published in
American journal of respiratory and critical care medicine
Millar, Jonathan E Bartnikowski, Nicole Passmore, Margaret R Obonyo, Nchafatso G Malfertheiner, Maximillian V von Bahr, Viktor Redd, Meredith A See Hoe, Louise Ki, Katrina K Pedersen, Sanne
...
Published in
American journal of respiratory and critical care medicine
Mesenchymal stromal cell therapy is a promising intervention for ARDS, although trials to date have not investigated its use alongside ECMO. Recent pre-clinical studies have suggested that combining these interventions may attenuate the efficacy of ECMO. To determine the safety and efficacy of mesenchymal stromal cell therapy in a model of ARDS and...
Kosinski, Samuel Mohammad, Rima A Pitcher, Mari Haezebrouck, Evan Coe, Antoinette B Costa, Deena K Prescott, Hallie C Iwashyna, Theodore J McSparron, Jakob I
Published in
American journal of respiratory and critical care medicine
Leary, Eileen B Zinchuk, Andrey Stone, Katie L Mehra, Reena
Published in
American journal of respiratory and critical care medicine
Fuertes, Elaine van der Plaat, Diana Portas, Laura Minelli, Cosetta
Published in
American journal of respiratory and critical care medicine
Crouser, Elliott D Maier, Lisa A Wilson, Kevin C Bonham, Catherine A Morgenthau, Adam S Patterson, Karen C Abston, Eric Bernstein, Richard C Blankstein, Ron Chen, Edward S
...
Published in
American journal of respiratory and critical care medicine
Background: The diagnosis of sarcoidosis is not standardized but is based on three major criteria: a compatible clinical presentation, finding nonnecrotizing granulomatous inflammation in one or more tissue samples, and the exclusion of alternative causes of granulomatous disease. There are no universally accepted measures to determine if each diag...
Cove, Matthew Kellum, John A
Published in
American journal of respiratory and critical care medicine
Boloña, Enrique Felix, Miguel Vanegas, Emanuel Vera Paz, Carlos Cherrez Ojeda, Ivan
Published in
American journal of respiratory and critical care medicine
Hayashi, Hiroaki Fukutomi, Yuma Mitsui, Chihiro Kajiwara, Keiichi Watai, Kentaro Kamide, Yosuke Nakamura, Yuto Hamada, Yuto Tomita, Yasuhiro Sekiya, Kiyoshi
...
Published in
American journal of respiratory and critical care medicine
Aspirin-exacerbated respiratory disease is characterized by severe asthma, non-steroidal anti-inflammatory drug hypersensitivity, nasal polyposis, and leukotriene overproduction. Systemic corticosteroid therapy does not completely suppress lifelong aspirin-hypersensitivity. Omalizumab efficacy against aspirin-exacerbated respiratory disease has not...
