Urias-Castro, Christian Arreguin-Arévalo, Jesus Alejandro Magee, Christianne Weber, Eric R Nett, Terry M
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Current methods to quantify kisspeptin (KP) are limited. To this end, a radioimmunoassay (RIA) specific for KP was developed and validated. We hypothesized that use of a RIA would reveal multiple hypothalamic regions as targets of negative seasonal feedback of estradiol on KP production in sheep. Ovariectomized (OVX) ewes bearing a subcutaneous imp...
Lorek, Daria Kedzierska, Anna Ewa Slawek, Anna Chelmonska-Soyta, Anna
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
The regulatory role of B lymphocytes in the pregnancy-induced maternal immune response is not well recognized. B lymphocytes function as antigen-presenting cells (APCs) and regulate Toll-like receptors and costimulatory molecule expression in response to intrinsic and extrinsic signals. Therefore, the aim of this study was to determine the expressi...
Lu, Yi Zhou, Qiong Lu, Jiang-Wen Wang, Wang-Sheng Sun, Kang
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Cortisol, which is regenerated from biologically inactive cortisone by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in human fetal membranes, may play an important role in human parturition. Recently, we have demonstrated that human fetal membranes are capable of de novo synthesis of serum amyloid A1 (SAA1), an acute-phase protein of inflamma...
McColl, Eliza R Piquette-Miller, Micheline
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Maternal immune activation (MIA) during pregnancy is associated with increased chances of neurodevelopmental disorders including schizophrenia and autism spectrum disorder (ASD). However, the exact mechanism through which MIA contributes to altered neurodevelopment is unknown. Due to the important role that amino acids play in neurodevelopment, alt...
Kobayashi, Mutsumi Nakashima, Akitoshi Yoshino, Osamu Yoshie, Masanori Ushijima, Akemi Ito, Masami Ono, Yosuke Shima, Tomoko Kawamura, Kazuhiro Ishizuka, Bunpei
...
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Premature ovarian insufficiency (POI) is a clinical syndrome defined by the loss of ovarian activity before 40 years old. An autoimmune mechanism is suggested to be involved in the development of POI. Therefore, we examined the relationship between peripheral blood regulatory T (Treg) cells and autoantibodies in POI. Thirty POI patients and 23 cont...
Lee, Ji Yeon Song, Haengseok Dash, Oyunbileg Park, Mira Shin, Na E McLane, Michael W Lei, Jun Hwang, Jong Yun Burd, Irina
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Maternal inflammation leads to preterm birth and perinatal brain injury. Melatonin, through its anti-inflammatory effects, has been shown to be protective against inflammation-induced perinatal adverse effects. However, the immunomodulatory effects of melatonin on preterm birth and prematurity-related morbidity remain unknown. We wanted to investig...
Schallmoser, Andreas Raab, Monika Karn, Thomas Königsberger, Sebastian Schmidt, Elke Breitenbach-Koller, Hannelore Sänger, Nicole
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Recent studies revealed that maternal and embryonic contributions impact on HLA-G protein expression and might contribute to pregnancy success or failure. The main objective of this study was to examine the paternal levels of the immunoregulatory soluble human leukocyte antigen-G (sHLA-G) protein in seminal plasma and testicular biopsy samples duri...
Guo, Yan-Lin
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Embryonic stem cells (ESCs) have been intensively studied as a promising cell source for regenerative medicine. The rapid advancements in the field have not only proven the feasibility of ESC-based cell therapy, but also led to a better understanding of pluripotent stem cells (PSCs) as a unique cell population at an early stage of embryogenesis. Re...
Moustafa, Sarah Joseph, Dana N Taylor, Robert N Whirledge, Shannon
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Chronic endometritis, inflammation of the uterizzvvne lining caused by common gram-negative bacterial strains or mycoplasma, has been associated with unexplained implantation failure and infertility. However, limited models of bacteria-induced implantation loss exist to study the molecular changes that occur in vivo. The goal of this study was to p...
Vinketova, Кameliya Karagyozov, Iliya Koleva, Vesselina Hristov, Michael Mourdjeva, Milena Sperandio, Markus Oreshkova, Tsvetelina
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
CD90 is a glycoprotein involved in leukocyte relocation and cell differentiation. CD90 is expressed in endothelial and stromal cells in human endometrium; however, its role in the remodeling of the decidual tissue during pregnancy is poorly understood. Here, we investigate how CD90 expression in decidual stromal cells (DSCs) is regulated. The nativ...
