Guo, Rong Jiang, Silin Zhang, Jianliang Yang, Quanli Gao, Liang Xia, Wei Tong, Lingxia Feng, Peiran Xu, Yan Zhang, Tao
...
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Recurrent pregnancy loss (RPL) is one of the big challenges of normal pregnancy. Immune dysregulation has been proposed for the key underline mechanisms of RPL. However, the essential roles of T cells, especially γδ T cells, have not been defined. Decidua were obtained from normal pregnancy women or recurrent pregnancy loss patients and the surface...
Kaushal, Khushboo Ayushi, Sharma, Nikhil Wadhwa, Nitya Misra, Sumit Bhatnagar, Shinjini Desiraju, Bapu Koundinya Thiruvengadam, Ramachandran Sopory, Shailaja
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
The objective of this study was to examine levels of cytokines across normal term pregnancy in an Indian population. Additionally we have also explored for possible associations between inflammatory markers and fetal growth parameters. A multiplex panel of 24 analytes was used to examine levels of inflammatory markers in maternal serum at three tim...
Zhang, Guo-Ming Zhuang, Zhao-Hui
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Fan, Yu-Xin Wu, Jiang-Hai Yin, Sun-Jun Zhou, Tao Huang, Yan-Hua Meng, Rui Wang, Ping He, Gong-Hao
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
FOXP3 single nucleotide polymorphisms (SNPs) were recently elucidated to influence the development of preeclampsia (PE), but the results on this issue still remained controversial. Thus, a meta-analysis was implemented to systematically investigate the roles of FOXP3 SNPs in PE. Eligible publications were identified by retrieving relevant electroni...
Cheng, Wei Wu, Yanan Wu, Huihua Zou, Qinyan Meng, Qingxia Wang, Fuxin Li, Huimin Xu, Yongle Zhao, Nannan Zhou, Ying
...
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Repeated implantation failure (RIF) is a daunting obstacle restricting the further improvement of embryo implantation rate (IR) and live birth rate (LBR). The beneficial effect of cyclosporine A (CsA) on reproductive outcomes of unexplained RIF(URIF) was explored after de novo embryo transfer (ET). A retrospective cohort study was conducted, compar...
Fernández, Laura Grasso, Esteban Soczewski, Elizabeth Gori, Soledad Calo, Guillermina Hauk, Vanesa Sabbione, Florencia Gallino, Lucila Martínez, Gustavo Irigoyen, Marcela
...
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Decidualized cells display an active role during embryo implantation sensing blastocyst quality, allowing the implantation of normal developed blastocysts and preventing the invasion of impaired developed ones. Here, we characterized the immune microenvironment generated by decidualized cells in response to soluble factors secreted by blastocysts t...
Vazquez, Jessica Chavarria, Melina Chasman, Deborah A Welch Schwartz, Rene Tyler, Chanel T Lopez, Gladys Fisher, Rachel C Ong, Irene M Stanic, Aleksandar K
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Mucosal-Associated Invariant T (MAIT) cells have been recently identified at the maternal-fetal interface. However, transcriptional programming of decidual MAIT cells in pregnancy remains poorly understood. We employed a multiomic approach to address this question. Mononuclear cells from the decidua basalis and parietalis, and control PBMCs, were a...
Tantengco, Ourlad Alzeus G de Castro Silva, Mariana Shahin, Hend Bento, Giovana Fernanda Cosi Cursino, Geovanna Cristofani Cayenne, Samir da Silva, Marcia Guimarães Menon, Ramkumar
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
A homeostatic balance between reactive oxygen species production and the antioxidant redox system is an important component of normal pregnancy. Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) preserves cellular homeostasis by enhancing the cell's innate antioxidant status to reduce oxidative stress and inflammatory damage to the cell during pre...
Zeng, Huiqian Han, Xinjia Zhu, Zhiqin Yu, Shengjun Mei, Shanshan Cheng, Xi Zhang, Weiqiang Zhang, Guanglan Fang, Dajun
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
The disruption of the inflammatory microenvironment in the uterus affects pregnancy outcome. However, the exact quantification and distribution of leukocyte subpopulations in the uterus in preeclampsia (PE) have not been clearly characterized. Inflammasomes promote the release of proinflammatory cytokines interleukin (IL)-β and IL-18. A higher expr...
Keenan-Devlin, Lauren S Caplan, Madeleine Freedman, Alexa Kuchta, Kristine Grobman, William Buss, Claudia Adam, Emma K Entringer, Sonja Miller, Gregory E Borders, Ann E B
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Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Inflammation as a risk factor for preterm birth is well-established. The primary objective of this analysis was to examine whether individual cytokines versus a composite indicator of mid-pregnancy inflammation are significantly associated with risk for adverse birth outcomes. A multi-site prospective study was conducted in a socio-demographically ...
