BLOOD PRESSURE TRAJECTORIES IN YOUTH AND HYPERTENSION RISK IN ADULTHOOD: THE 1970 BRITISH COHORT STUDY
Published in American Journal of Epidemiology
Polybrominated Diphenyl Ethers, Polybrominated Biphenyls, and Risk of Papillary Thyroid Cancer: A Nested Case-Control St...
...Published in American Journal of Epidemiology
A nested case-control study was carried out using data from the US Department of Defense cohort between 2000 and 2013 to investigate the associations of papillary thyroid cancer (PTC) with serum concentrations of polybrominated diphenyl ethers and polybrominated biphenyls. This study included 742 histologically confirmed PTC cases (in 341 women and...
Methods for Dealing With Missing Covariate Data in Epigenome-Wide Association Studies.
Published in American journal of epidemiology
Multiple imputation (MI) is a well-established method for dealing with missing data. MI is computationally intensive when imputing missing covariates with high-dimensional outcome data (e.g., DNA methylation data in epigenome-wide association studies (EWAS)), because every outcome variable must be included in the imputation model to avoid biasing a...
Population-Level Sexual Mixing According to HIV Status and Preexposure Prophylaxis Use Among Men Who Have Sex With Men i...
...Published in American Journal of Epidemiology
Using cross-sectional survey data (Engage, 2017–2018) from 1,137 men who have sex with men, ≥16 years old, in Montreal, we compared observed human immunodeficiency virus (HIV) seroconcordance in previous-6-months’ sexual partnerships with what would have been observed by chance if zero individuals serosorted. Of 5 recent partnerships where both ind...
Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- an...
...Published in American Journal of Epidemiology
Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment in the United States and Canada might differ among key populations. Given the difference in substance use among key populations and the current opioid epidemic, drug- and alcohol-related deaths might be contributing to the...
Incidence of initial renal replacement therapy over the course of kidney disease in children.
Published in American journal of epidemiology
The prospective Chronic Kidney Disease in Children cohort with data collected from 2003 to 2018 provided the first opportunity to characterize the incidence of renal replacement therapy (RRT) initiation over the life course of pediatric kidney diseases. Parametric generalized gamma models were fit and extrapolated for overall RRT, and by specific m...
The Changing Science of HIV Epidemiology in the U.S.
Published in American journal of epidemiology
In 1984, a large prospective study of the natural history of HIV infection, the Multicenter AIDS Cohort Study (MACS), was established; ten years later, the Women's Interagency HIV Study (WIHS) was launched. Motivated by the merger and redesign of these long-standing HIV cohort studies in 2019, we review ways in which HIV epidemiology in the U.S. ha...
Invited Commentary: The Disillusionment of Developmental Origins of Health and Disease (DOHaD) Epidemiology
Published in American Journal of Epidemiology
The developmental origins of health and disease (DOHaD) model promises a greater understanding of early development but has left unresolved the balance of risks and benefits to offspring of medication use during pregnancy. Masarwa et al. ( Am J Epidemiol . 2018;187(8):1817–1827) conducted a meta-analysis of the association between in utero acetamin...
Associations Between Midlife (but Not Late-Life) Elevated Coronary Heart Disease Risk and Lower Cognitive Performance: R...
Published in American Journal of Epidemiology
It is unclear how coronary heart disease (CHD) risk across the adult life span affects late-life cognition. We estimated associations of midlife and late-life elevated CHD risk with cognitive trajectories (general cognitive performance, processing speed/executive function, memory) in later life (after age 55 years or age 70 years) among 2,892 Frami...
Longitudinal Changes in the Genital Hiatus Preceding the Development of Pelvic Organ Prolapse.
Published in American journal of epidemiology
