Fox, Matthew P D'Agostino McGowan, Lucy James, Bryan D Lessler, Justin Mehta, Shruti H Murray, Eleanor J
Published in
American journal of epidemiology
In May 2020, the Journal published an opinion piece by a member of the Editorial Board, in which the author reviewed several papers and argued that using hydroxychloroquine (HCQ) + azithromycin (AZ) early to treat symptomatic coronavirus disease 2019 (COVID-19) cases in high-risk patients should be broadly applied. As members of the Journal's Edito...
Lee, Daejoong Heo, Kyungmoo Seo, Yongseok Ahn, Hyerim Jung, Kyungran Lee, Sohyun Choi, Hyeseung
Published in
American journal of epidemiology
The spread of coronavirus disease 2019 (COVID-19) is causing an unprecedented crisis around the world, with South Korea being no exception. South Korea experienced a surge of COVID-19 cases on February 19, 2020, but was able to flatten the COVID-19 curve in only 20 days without enforcing lockdown measures that restrict the freedom and movement of p...
von Cube, Maja Wolkewitz, Martin Schumacher, Martin Hazard, Derek
Published in
American Journal of Epidemiology
Hitchings, Matt D T Dean, Natalie E Garcia-Carreras, Bernardo Hladish, Thomas J Huang, Angkana T Yang, Bingyi Cummings, Derek A T
Published in
American Journal of Epidemiology
Comparison of coronavirus disease (COVID-19) case numbers over time and between locations is complicated by limits to virologic testing to confirm severe acute respiratory syndrome coronavirus 2 infection. The proportion of tested individuals who have tested positive (test-positive proportion, TPP) can potentially be used to inform trends in incide...
Renoux, Christel Azoulay, Laurent Suissa, Samy
Published in
American Journal of Epidemiology
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented effort to generate real-world evidence on the safety and effectiveness of various treatments. A growing number of observational studies evaluating the effects of certain drugs have been conducted, i...
Dionne-Odom, Jodie Klipstein, Sigal
Published in
American Journal of Epidemiology
The emergence of the novel coronavirus COVID-19 presented the field of reproductive medicine with many challenges due to an absence of data to guide clinical decision making and inform patient counseling and management in the early days of the pandemic. Epidemiological studies rapidly filled in key gaps in our understanding of the susceptibility of...
Iversen, Inge Brosbøl Mohr, Mette Skovgaard Vestergaard, Jesper Medom Stokholm, Zara Ann Kolstad, Henrik Albert
Published in
American journal of epidemiology
Exposure to industrial solvents has been associated with encephalopathy. Styrene is a neurotoxic industrial solvent, and we investigated the long-term risk of encephalopathy and unspecified dementia following styrene exposure. We followed 72,465 workers in the reinforced plastics industry in Denmark (1977-2011) and identified incident cases of ence...
Labrecque, Jeremy A Hunink, Myriam M G Ikram, M Arfan Ikram, M Kamran
Published in
American journal of epidemiology
Case-control studies are an important part of the epidemiologic literature, yet confusion remains about how to interpret estimates from different case-control study designs. We demonstrate that not all case-control study designs estimate odds ratios. On the contrary, case-control studies in the literature often report odds ratios as their main para...
Kahn, Rebecca Kennedy-Shaffer, Lee Grad, Yonatan H Robins, James M Lipsitch, Marc
Published in
American journal of epidemiology
The extent and duration of immunity following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are critical outstanding questions about the epidemiology of this novel virus, and studies are needed to evaluate the effects of serostatus on reinfection. Understanding the potential sources of bias and methods for alleviating ...
Gail, Mitchell H Wan, Yunhu Shi, Jianxin
Published in
American journal of epidemiology
A simple method to analyze microbiome beta-diversity computes mean beta-diversity distances from a test sample to standard reference samples. We used reference stool and nasal samples from the Human Microbiome Project and regressed an outcome on mean distances (2 degrees-of-freedom (df) test) or additionally on squares and cross-product of mean dis...
