Akhtar, Nabeel H. Khosravi-Hafshejani, Touraj Akhtar, Daud Dhadwal, Gurbir Kanani, Amin
Published in
Allergy, Asthma & Clinical Immunology
BackgroundAtopic dermatitis is a common chronic skin disease that can occur in pregnancy. Current treatments include topical and systemic glucocorticoids and cyclosporine. Presently, the only biologic approved for atopic dermatitis is dupilumab with limited data available regarding its safety profile in pregnancy.Case presentationWe report a case o...
Cyr, Chloe Cyr, Michael Quirt, Jaclyn Connors, Lori
Published in
Allergy, Asthma & Clinical Immunology
BackgroundThere is currently little Canadian data to assess how well traditional time-based residency training programs have prepared residents for careers in Clinical Immunology and Allergy (CIA). This study aims to identify the perceived preparedness of residents in various areas of practice upon the completion of a Canadian CIA residency trainin...
Park, Han-Ki Yoo, Seok-Ju Kim, Taek Soo Kim, Byung-Keun Jang, Sekyung Kim, Sung Yeon Lee, Kwan
Published in
Allergy, Asthma & Clinical Immunology
BackgroundStaphylococcus aureus (SA) nasal carriage (SA carriage) and IgE-sensitization to SA enterotoxin (SE IgE-sensitization) are known to be associated with chronic airway disease.ObjectiveThis study aimed to evaluate the differences in risk factors, type 2 inflammation and respiratory symptoms between SA carriage and SE IgE-sensitization.Metho...
Sultafa, Jessica McKibbon, Lundy Roberts, Hannah Sarraj, Jumana Kim, Harold
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Allergy, Asthma & Clinical Immunology
BackgroundFood Protein-Induced Enterocolitis Syndrome (FPIES) is a non-IgE mediated food allergy most commonly presenting in infants. The most common food triggers include soy, cow’s milk and grains. Symptoms may include intractable vomiting, diarrhea, lethargy, pallor, abdominal distention, hypotension and/or shock. Oral food challenges (OFCs) giv...
Khani, Leila Jazayeri, Mir Hadi Nedaeinia, Reza Bozorgmehr, Mahmood Nabavi, Seyed Masood Ferns, Gordon A.
Published in
Allergy, Asthma & Clinical Immunology
BackgroundMultiple sclerosis (MS) and neuromyelitis optica syndrome disease (NMOSD) are inflammatory diseases of the central nervous system. The pathogenesis and treatments for these two conditions are very different. Natural killer (NK) and natural killer T (NKT) cells are immune cells with an important role in shaping the immune response. B cells...
Maurer, Marcus Magerl, Markus Aygören-Pürsün, Emel Bork, Konrad Farkas, Henriette Longhurst, Hilary Kiani‑Alikhan, Sorena Bouillet, Laurence Boccon-Gibod, Isabelle Cancian, Mauro
...
Published in
Allergy, Asthma & Clinical Immunology
BackgroundHereditary angioedema (HAE) is characterized by potentially severe and life-threatening attacks of localized swelling. Prophylactic therapies are available, including attenuated androgens. Efficacy of attenuated androgens has not been assessed in large, randomized, placebo-controlled trials and can be associated with frequent, and sometim...
Álvarez-Santos, Mayra D. Álvarez-González, Marisol Eslava-De-Jesus, Elizabeth González-López, Angel Pacheco-Alba, Ivonne Pérez-Del-Valle, Yazmín Rojas-Madrid, Rodrigo Bazán-Perkins, Blanca
Published in
Allergy, Asthma & Clinical Immunology
BackgroundAirway obstruction (AO) in asthma is driven by airway smooth muscle (ASM) contraction. AO can be induced extrinsically by direct stimulation of ASM with contractile agonists as histamine, or by indirect provocation with antigens as ovalbumin, while the airway tone is dependent on intrinsic mechanisms. The association of the ASM phenotypes...
Sompornrattanaphan, Mongkhon Tongdee, Ranista Wongsa, Chamard Jitmuang, Anupop Thongngarm, Torpong
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Allergy, Asthma & Clinical Immunology
BackgroundNodular regenerating hyperplasia (NRH) is the most common liver involvement in common variable immunodeficiency (CVID). Most patients are asymptomatic with gradually increasing alkaline phosphatase (ALP) and mildly elevated transaminase enzymes over the years. We report the first case of fatal liver mass rupture in a CVID patient with pro...
Wang, Jingjing Zhang, Zeyi Chen, Ou
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Allergy, Asthma & Clinical Immunology
BackgroundAsthma is a common multifactorial disease affecting millions worldwide. The Barker hypothesis postulates an association between later onset disease risk and energy exposure in utero. Birth weight corrected for gestational age is better for measuring the infant size, which reflects energy exposure in utero. Findings on asthma and birth wei...
Guilarte, Mar Sala-Cunill, Anna Baeza, María Luisa Cabañas, Rosario Hernández, María Dolores Ibañez, Ethel de Larramendi, Carlos Hernando Lleonart, Ramon Lobera, Teófilo Marqués, Luis
...
Published in
Allergy, Asthma & Clinical Immunology
BackgroundThe Icatibant Outcome Survey (IOS) is an international registry monitoring the use of icatibant, a bradykinin B2 receptor antagonist indicated for the acute treatment of hereditary angioedema (HAE) attacks. Our goal was to assess disease characteristics and icatibant treatment outcomes in patients with HAE due to C1 inhibitor deficiency (...
