Devi, Ratna Kanitkar, Komal Narendhar, R. Sehmi, Kawaldip Subramaniam, Kannan
Published in
Advances in Therapy
Low- and middle-income countries (LMICs) are challenged with a disproportionately high burden of noncommunicable diseases (NCDs) and limited healthcare resources at their disposal to tackle the NCD epidemic. Understanding the patient journey for NCDs from the patients’ perspective can help healthcare systems in these settings evolve their NCD care ...
Reda, Ashraf Almahmeed, Wael Dobrecky-Mery, Idit Huang, Po-Hsun Juarez-Herrera, Ursulo Ranjith, Naresh Sayre, Tobias Urina-Triana, Miguel
Published in
Advances in therapy
Patients who have experienced an acute coronary syndrome (ACS) are at very high risk of recurrent atherosclerotic cardiovascular disease (CVD) events. Dyslipidaemia, a major risk factor for CVD, is poorly controlled post ACS in countries outside Western Europe and North America, despite the availability of effective lipid-modifying therapies (LMTs)...
Best, Jennie H. Mohan, Shalini V. Kong, Amanda M. Patel, Krish Pagel, John M. Ivanov, Boris Brawley, Otis W. Jariwala-Parikh, Krutika Zazzali, James L. Pauk, John
...
Published in
Advances in Therapy
Introduction Coronavirus disease 2019 (COVID-19) can present as a range of symptoms, from mild to critical; lower pulmonary involvement, including pneumonia, is often associated with severe and critical cases. Understanding the baseline characteristics of patients hospitalized with COVID-19 illness is essential for effectively targeting clinical ca...
Webster, Lynn R. Hansen, Erik Cater, Jacqueline Smith, Thomas
Published in
Advances in Therapy
Introduction Buprenorphine is a partial μ-opioid receptor agonist that, unlike full μ-opioid receptor agonists, has been shown to have a ceiling effect on respiratory depression. Buprenorphine buccal film (BBF) is approved by the US Food and Drug Administration for use in patients with chronic pain severe enough to require daily, around-the-clock, ...
Taheri, Hoda Malek, Mojtaba Ismail-Beigi, Faramarz Zamani, Farhad Sohrabi, Masoudreza Reza babaei, Mohammad Khamseh, Mohammad E.
Published in
Advances in Therapy
Introduction Despite the high prevalence of non-alcoholic fatty liver disease (NAFLD) and its associated co-morbidities, no efficient treatment in a high percentage of individuals is available. Beneficial effects of sodium–glucose co-transporter 2 inhibitors on fatty liver have been investigated in people with type 2 diabetes (T2DM). The aim of thi...
Li, Yan Ming, Jeffrey E. Kong, Fangyuan Yin, Huiqiu Zhang, Linlin Bai, Haihong Liu, Huijuan Qi, Lu Wang, Yu Xie, Fang
...
Published in
Advances in Therapy
Introduction Simultaneous administration of acetylsalicylic acid (ASA) and clopidogrel has demonstrated efficacy in the treatment of acute coronary syndrome. Clopidogrel + ASA in a fixed-dose combination (FDC) provides a pharmaceutical option to enhance adherence to the coadministration of dual antiplatelet therapy (DAPT). Herein, we evaluate the b...
Minnella, Angelo Maria Maceroni, Martina Picardi, Stefano Maria Placidi, Giorgio De Siena, Elisa Rizzo, Stanislao Falsini, Benedetto
Published in
Advances in Therapy
Introduction Cataract surgery can be associated with vision-threatening complications in patients with diabetes. This study aimed to assess the functional and anatomic outcomes of the intravitreal dexamethasone (DEX) implant, administered at the time as cataract surgery, in patients with diabetic retinopathy and diabetic macular edema (DME). Method...
Stein Gold, Linda Alonso-Llamazares, Javier Lacour, Jean-Philippe Warren, Richard B. Tyring, Stephen K. Kircik, Leon Yamauchi, Paul Lebwohl, Mark
Published in
Advances in Therapy
Background Psoriasis vulgaris is commonly treated with topical corticosteroids and vitamin D analogues. Although potent and super-potent topical corticosteroids are very effective at clearing psoriasis, with short-term reactive treatment durations, symptoms usually recur after treatment discontinuation, necessitating long-term disease management st...
Stolle, Lucas B Nalamasu, Rohit Pergolizzi, Joseph V Jr Varrassi, Giustino Magnusson, Peter LeQuang, JoAnn Breve, Frank
Published in
Advances in therapy
In the light of the COVID-19 pandemic, anti-vaccine sentiments have been on the rise, with a recent seminal study on the development of anti-vaccine views in social media even making its way into Nature Communications. Yet, with the current scientific consensus being in overwhelming agreement over the safety and efficacy of vaccines, many scientist...
Bruyère, Olivier Dardenne, Nadia Donneau, Anne-Françoise Reginster, Jean-Yves
Published in
Advances in Therapy
Introduction The recent CONCEPT study showed that 800 mg/day of pharmaceutical-grade chondroitin sulfate (CS) was superior to placebo and similar to celecoxib in reducing pain and improving function over 6 months in patients with symptomatic knee osteoarthritis (OA). We investigate, in the present study, whether a responder profile to CS could be d...
