Nuytemans, Laure Sys, Gwen Creytens, David Lapeire, Lore
Published in
Acta clinica Belgica
Background: The prognosis and treatment of metastatic osteosarcoma have not changed in the last decades and the responses to chemotherapy in this setting are disappointing. In the past years, immunotherapy has found its place in the treatment of different tumor types. Its role in the treatment of sarcomas, and in particular osteosarcoma, is less cl...
Decalf, Veerle Bower, Wendy Rose, Georgie Petrovic, Mirko Pieters, Ronny Eeckloo, Kristof Everaert, Karel
Published in
Acta clinica Belgica
Objectives: Although nocturia is a risk factor for incident falls in the community, studies are required to gain an understanding of incident falls related to nocturnal toileting in hospitals. The aim of this study is to describe the prevalence and characteristics of incident falls in adult hospitalized patients related to nocturnal toileting.Metho...
Cattoir, Lien Vercauteren, Koen O A Padalko, Elizaveta De Beenhouwer, Hans Van Vaerenbergh, Kristien Boel, An
Published in
Acta clinica Belgica
Objectives: Hepatitis E virus (HEV) genotype 3 is an emerging pathogen in developed countries. We evaluated the performance of two new serological assays for the detection of HEV, VIDAS® anti-HEV IgM and IgG. Methods: VIDAS® assays were performed on 77 clinical samples: 68 samples from patients suspected for HEV infection and 9 samples which previo...
Coche, Sophie Cornet, Georges Morelle, Johann Labriola, Laura Kanaan, Nada Demoulin, Nathalie
Published in
Acta clinica Belgica
Background: Pneumocystis jirovecii associated pneumonia is a potentially life-threatening opportunistic infection, occurring most frequently in the first year after renal transplantation, and may be associated with hypercalcemia. Clinical presentation:We report the case of a renal transplant recipient presenting with Pneumocystis jirovecii associat...
Abdelwahed, Mayssa Maaloul, Ines Benoit, Valerie Hilbert, Pascale Hachicha, Mongia Kamoun, Hassen Keskes-Ammar, Leila Belguith, Neila
Published in
Acta clinica Belgica
Objective: Juvenile nephronophthisis (NPHP) is an autosomal recessive cystic disease of the kidney. It represents the most frequent genetic cause of chronic renal failure in children. Methods: we investigated clinical and molecular features in two children with Juvenile nephronophthisis using firstly Multiplex ligation-dependent probe amplification...
Van Ham, Jonas Janssens, Ann Raddoux, Jolien Raets, Els Delforge, Michel
Published in
Acta clinica Belgica
Objective: The aim of this study was to evaluate the administration of intravenous immunoglobulin (IVIg) solutions (5% vs. 10%) in hematological patients suffering from a secondary immunodeficiency (SID) to optimize infusion duration and hospitalization time. Design: A monocentric, observational study in 30 patients with secondary hypogammaglobulin...
Răcătăianu, Nicoleta Leach, Nicoleta V Bolboacă, Sorana D Soran, Maria Loredana Opriş, Ocsana Dronca, Eleonora Valea, Ana Ghervan, Cristina
Published in
Acta clinica Belgica
Objectives: The mechanisms of obesity-associated thyroid dysfunction in children are incompletely deciphered. We aimed to evaluate whether visceral adipose tissue (VAT), insulin resistance (IR), inflammation, oxidative stress (OS) are involved in thyroid morpho-functional changes in pubertal obese children. Methods: We recruited 43 obese pubertal c...
Ulpiano Trillig, Antonio Miendje Deyi, Véronique Y Youatou, Pierre Konopnicki, Deborah
Published in
Acta clinica Belgica
Ecthyma gangrenosum (EG) is a potentially lethal skin infection, most commonly due to Pseudomonas aeruginosa with bacteremic dissemination and affecting mostly immunocompromised patients. We present two cases of EG in two men in Belgium recently admitted to our hospital, caused by a suspected coinfection by group A Streptococcus and Staphylococcus ...
Vanwonterghem, Yuran Shadid, Samyah
Published in
Acta clinica Belgica
We describe a case of a woman with uncomplicated Type 2 diabetes mellitus, presenting with severe burning pains and intense redness of the legs, for which only cooling could provide relief. Although the description was classic of erythromelalgia, the lack of familiarity of the disorder caused considerable doctor's delay as well as the erroneous adv...
Fontaine, Christel Claes, Nele Graas, Marie-Pascale Samani, Khalil Kargar Vuylsteke, Peter Vulsteke, Christof
Published in
Acta clinica Belgica
Objectives: This study evaluated the effect of lipegfilgrastim, a glycopegylated granulocyte-colony stimulating factor, used as primary (PP) or secondary prophylaxis (SP) on chemotherapy (CT) treatment modifications, as well as the incidence of CT-induced neutropenic events in adult patients receiving cytotoxic CT with or without biological therapy...