Lambert, E Hollebosch, S van Praet, C Van Bruwaene, S Duck, L De Roock, W van Wambeke, S Ghysel, C Ameye, F Schatteman, P
...
Published in
Acta clinica Belgica
Abiraterone acetate + prednisone (AAP) and docetaxel have proven their efficacy in the treatment of patients with newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC) in clinical trials. However, real-world data are scarce. The goal of this study is to evaluate real-world data on the efficacy and safety of these therapies in mHSPC p...
Boogaerts, Hélène L F Smits, Patrick Hans, Guy Bouly, Liza Coeck, Eline Vandamme, Sarah Jansens, Hilde Goossens, Herman Matheeussen, Veerle
Published in
Acta clinica Belgica
The B.1.617.2 SARS-CoV-2 or Delta variant, first detected in India, has shown a rapid global spread due to its high transmissibility and now represents more than 99% of the currently circulating variants in Europe. In May 2021, two ships that had recently arrived in the Port of Antwerp reported crew members with COVID-like symptoms. SARS-CoV-2 RNA ...
Wauthier, Loris Delefortrie, Quentin Eppe, Nicolas Vankerkhoven, Patrick Wolff, Eva Dekeyser, Mélanie Cirriez, Jean-Michel Grimmelprez, Alexandre
Published in
Acta clinica Belgica
Health care workers (HCWs) are at the frontline for combatting the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To describe recent or past infections, the novel development of serological assays enabled the assessment of the immune response developed in coronavirus disease (COVID-19). Here, we investigate SARS-CoV-...
Van Leeuwen, Ellen Anthierens, Sibyl van Driel, Mieke L De Sutter, An De Beir, Rani Christiaens, Thierry
Published in
Acta clinica Belgica
The rise in long-term antidepressant use is concerning. Long-term antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of adverse events and generate unnecessary costs. In order to mitigate these risks, patients views about their antidepressants and how to discontinue need to be taken into account. We aimed to exp...
Jorissen, Winde Annemans, Lieven Louis, Nicolas Nilsson, Andreas Willis, Michael
Published in
Acta clinica Belgica
The Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial showed reduced renal and cardiovascular (CV) events in patients with type 2 diabetes (T2D) and diabetic kidney disease (DKD) treated with canagliflozin 100 mg added to Standard of Care (SoC) versus SoC alone. This led to an extension of ...
Dupon, Valérie Arnaert, Stijn Van Haute, Eline Vulsteke, Friedel Diet, Günter De Schoenmakere, Gert
Published in
Acta clinica Belgica
Aseptic meningitis is a rare, but possible severe side effect after SARS-CoV-2 Pfizer/BioNTech vaccination. Recently, a first case of aseptic meningitis after the first shot of mRNA-BNT162b2 SARS-CoV-2 (Pfizer/BioNTech) vaccine was reported. We present the first case of a 34-year-old woman without relevant medical history developing aseptic meningi...
Fraeyman, Norbert de Bacquer, Dirk Clays, Els Fiers, Tom Godderis, Lode Verhaeghe, Rik Viaene, Leen Mortier, Eric
Published in
Acta clinica Belgica
Health-care organizations are facing a high burden of ergonomic occupational accidents, and prevention is a continuous point of interest. In this manuscript, we describe the characteristics of ergonomic accidents in a large Belgian university hospital and discuss the value of near misses. Combining databases, we identified the frequency [number of ...
Vincken, Stefanie Verbanck, Sylvia Hanon, Shane Vanderhelst, Eef
Published in
Acta clinica Belgica
Prevalence of MRSA in patients with CF has risen over the past decades, and chronic infection with MRSA is associated with worse outcome in this patient group. This retrospective observational study investigated long-term eradication rate in pediatric and adult CF patients with chronic MRSA infection, using a 6-month eradication regimen containing ...
Goñi Ros, Nuria González-Tarancón, Ricardo Sienes Bailo, Paula Salvador-Ruperez, Elvira Puzo Bayod, Martín Puzo Foncillas, José
Published in
Acta clinica Belgica
Fish-eye disease (FED) is due to a partial deficiency in LCAT activity. Nevertheless, Familial lecithin-cholesterol acyltransferase deficiency (FLD), also called Norum disease, appears when the deficiency is complete. They are both rare genetic disorders inherited in an autosomal recessive manner. Clinical signs include decreased circulating HDL ch...
Sluyts, Yasmine Vanherpe, Pieternel Amir, Rizvana Vanhoenacker, Filip Vermeersch, Pieter
Published in
Acta clinica Belgica
It is well recognized that nitrous oxide abuse can lead to vitamin B12 deficiency presenting with neurological complications. Nevertheless, establishing this diagnosis can be challenging, and treatment guidelines are lacking. In this paper, we present a case series of eight patients and discuss the diagnostic challenges and treatment options for vi...
