Azevedo, Maira de Robertis de-Lima-Oliveira, Marcelo Belon, Alessandro Rodrigo Brasil, Sérgio Teixeira, Manoel Jacobsen Paiva, Wellingson Silva Bor-Seng-Shu, Edson
Published in
Acta Cirúrgica Brasileira
Purpose: To determine the normal optical nerve sheath (ONS) diameter ultrasonography (ONSUS) and evaluate the possible effects of drugs on ONS diameter during anesthetic induction in healthy pigs. Methods: Healthy piglets were divided into three groups: a control group, that received xylazine and ketamine (X/K); other that received xylazine, ketami...
Wang, Jiyuan Chen, Yu
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Acta Cirúrgica Brasileira
Purpose: To explore the mechanism and investigate the protective effect of hydroxysafflor yellow A (HSYA) on renal oxidative stress, which cyclosporine A (CsA) induces. Methods: HK-2 cells were treated with CsA to get CsA-induced oxidative stress. The effects on oxidative stress and apoptosis of HK-2 cells were detected. The contents of SOD, MDA, G...
Chen, Rongchang Xu, Lijiao Zhang, Xu Sun, Guibo Zeng, Wenying Sun, Xiaobo
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Acta Cirúrgica Brasileira
Purpose: To investigate the protective effects of Shenkang injection (SKI) on adenine-induced chronic renal failure (CRF) in rat. Methods: Sprague Dawley rats were randomly divided into five groups: control, model, and SKI groups (5, 10, 20 mL/kg). Rats in model and SKI groups were treated with adenine i.g. at a dose of 150 mg/kg every day for 12 w...
dos Santos, Deivid Ramos de Araújo, Nayara Pontes Teixeira, Renan Kleber Costa Bentes, Lívia Guerreiro de Barros Giubilei, Dante Bernardes Chaves, Rosa Helena de Figueiredo Gonçalves, Arnaldo Algaranhar Yasojima, Edson Yuzur de Barros, Rui Sergio Monteiro
Published in
Acta Cirúrgica Brasileira
Purpose: To describe the anatomical aspects of the cervical rootlets and to quantify the number of rootlets that compose C1 to T1. Methods: Twenty male rats were used in this study. The dorsal rootlets from C1 to T1 were analyzed. To study the ventral rootlets, the posterior root avulsion was performed using a microhook, allowing exposure of the ve...
Tao, Lijun Xu, Hongbo He, Qianggui
Published in
Acta Cirúrgica Brasileira
Purpose: To explore the influence of milk fat globule-EGF factor 8 protein (MFGE8) on blunt abdominal injury in Sprague Dawley (SD) rats through the RhoA/ROCK signaling pathway. Methods: The blunt abdominal injury model was generated in SD rats. A total of 44 rats was randomly assigned into three groups. Rat blunt abdominal injury was assessed by t...
Borges, Eline Lima Amorim, Gilmara Lopes de Miranda, Marina Barcelos Martins, Flaviano dos Santos Guedes, Antônio Carlos Martins Sampaio, Kinulpe Honorato Spira, Josimare Aparecida Otoni Barcelos, Lucíola da Silva
Published in
Acta Cirúrgica Brasileira
Purpose: To evaluate a biofilm model of Pseudomonas aeruginosa in excisional cutaneous wound in mice. Methods: Preclinical, translational study conducted with 64 C57BL/6 mice randomly assigned to control and intervention groups. Evaluation was on days D0, D3, D5, D7 and D10 of wound making. The profile of biofilm formation and induction was evaluat...
Wang, Li Jiao, Wei Wu, Jiayu Zhang, Jing Tang, Min Chen, Yang
Published in
Acta Cirúrgica Brasileira
Purpose: Spontaneous intracerebral hemorrhage (ICH) is a major public health problem with a huge economic burden worldwide. Ulinastatin (UTI), a serine protease inhibitor, has been reported to be anti-inflammatory, immune regulation, and organ protection by reducing reactive oxygen species production, and inflammation. Necroptosis is a programmed c...
de Souza, Francisco Fábio Pereira Pérez-Guerrero, Jesús Alberto Gomes, Maria Janaína Paula Cavalcante, Fábio Lima de Souza, Men de Sá Moreira Filho Castro-Silva, Igor Iuco
Published in
Acta Cirúrgica Brasileira
Purpose: Poultry by-products can contribute as an innovative natural source for the development of composites based on polymers and minerals aiming at bone regeneration. The objective of this study was the physicochemical and biological characterization of collagen-based hydrogels crosslinked with ultraviolet (UV)-riboflavin. Methods: Pure hydrogel...
Barros, Rui Sergio Monteiro de Santos, Deivid Ramos Dos Teixeira, Renan Kleber Costa Araújo, Nayara Pontes de Somensi, Danusa Neves Candido, Atylla de Andrade
Published in
Acta cirurgica brasileira
To study the anatomorphometry of the plexus brachialis (PB) of rats under a high-definition video system. Ten male Wistar rats discarded from other research that did not interfere in the morphology of the animal, respecting the principle of reduction, were used. All animals were submitted to the same protocol. Initially, the cervical region was sha...
Ji, Yanzhao Zhou, Weidong Tan, Wei Chen, Zewei Lu, Hanqi You, Yanting Tian, Chunyang Zhou, Xinghong Zhou, Lin Luo, Ren
...
Published in
Acta Cirúrgica Brasileira
Purpose: To evaluate the protective effect of Cuscuta chinensis Lam. polysaccharides (PCCL) on 5-fluorouracil-(5-FU)-induced intestinal mucositis (IM) in mice. Methods: PCCL was orally administered at a dose of 20 mg·kg–1 for 7 days and its protective effect on 5-FU-induced IM (5-FU, 50 mg·kg–1 for 5 days) was evaluated by monitoring changes in bod...
