Zhang, Jing Ma, Yan-Xia Zeng, Yu-Qiang Zhang, Shuang-Feng Teng, Zhao-Qian Gao, Jun Liu, Chang-Mei
Published in
Acta Biochimica et Biophysica Sinica
The permanent disability after the central nervous system (CNS) injury is due to the weakened regeneration ability of the damaged axon, resulting in the loss of the rebuilding functional relationship with the original targets. One determinant of successful axon regeneration is the activation of intrinsic axon growth ability of injured neurons. Micr...
Li, Chunyan Zhang, Hongliang Xie, Yuanyuan Liu, Shenghua Zhao, Ranxu Huang, Jian Huang, Jie Wei, Yingjie
Published in
Acta Biochimica et Biophysica Sinica
CMYA1 (cardiomyopathy-associated protein 1, also termed Xin) localizes to the intercalated disks (ICDs) of the myocardium and functions to maintain ICD structural integrity and support signal transduction among cardiomyocytes. Our previous study showed that CMYA1 overexpression impairs the function of gap junction intercellular communication proces...
Deng, Zhiqin Lin, Zicong Zhong, Qing Lu, Minqiang Fang, Huankun Liu, Jianquan Duan, Li Chen, Lixin Wang, Liwei Wang, Daping
...
Published in
Acta Biochimica et Biophysica Sinica
Persistent hypotonic and inflammatory conditions in the joint cavity can lead to the loss of cartilage matrix and cell death, which are the important mechanisms of osteoarthritis (OA) onset. Previous studies have confirmed that the existence of a hypotonic environment is a red flag for inflammation, as hypotonic environment induces the opening of t...
Luo, Jinwen Zhu, Xiao Jian, Jie Chen, X u Yin, Kai
Published in
Acta Biochimica et Biophysica Sinica
The coronavirus disease-2019 (COVID-19) caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly developed into a global pneumonia pandemic. At present, COVID-19 has caused more than 70,000,000 confirmed cases with over 1,500,000 deaths worldwide, as reported by WHO. Cardiovascular disease is the majo...
Qi, Huan Ma, Mingliang Lai, Danyun Li, Yang Zhang, Fucheng Tao, Sheng-ce
Published in
Acta Biochimica et Biophysica Sinica
Zhao, Zhijuan Cui, Xiaodong Ma, Xiaoli Wang, Zhuanhua
Published in
Acta Biochimica et Biophysica Sinica
The self-nanoemulsifying drug delivery system has shown many advantages in drug delivery. In this study, a self-nanoemulsifying drug delivery system of buckwheat flavonoids was prepared for enhancing its antioxidant activity and oral bioavailability. A nanoemulsion of buckwheat flavonoids was developed and characterized, and its antioxidant, in vit...
Bosevski, Marijan Krstevski, Gorjan Bosevska, Golubinka Kapsarov, Kosta Dodic, Emilija Feehan, Jack Stojanoska, Lily Apostolopoulos, Vasso
Published in
Acta Biochimica et Biophysica Sinica
Shi, Rongfeng Lian, Weishuai Jin, Yinpeng Cao, Chuanwu Han, Shilong Yang, Xiaohu Zhao, Suming Li, Maoquan Zhao, Hui
Published in
Acta Biochimica et Biophysica Sinica
Diabetic foot ulcer (DFU) is one of diabetic complications, which is frequently present and tormented in diabetes mellitus. Most multipotent mesenchymal stromal cells (MSCs) are capable of immune evasion, providing an allogeneic, ready-to-use, cell product option for therapeutic applications. The beneficial effect of MSCs for the treatment of a var...
Xu, Guangmeng Sun, Yajuan He, Huaiqiang Xue, Qiuli Liu, Yajie Dong, Lihua
Published in
Acta Biochimica et Biophysica Sinica
In this study, we aimed to explore the effect of TrkB-PLC/IP3 pathway on intestinal inflammatory factors and enterocyte apoptosis in mice with colitis. The mouse model of ulcerative colitis was established by medication, and 40 SPF C57BL/6J mice (8 weeks old) were randomly divided into normal group (healthy mice, n = 10), control group (sham-operat...
Zhang, Yiwen Zhang, Xiaoxia Xing, Zumin Tang, Shuyi Chen, Hanwen Zhang, Zhongqi Li, Jiyuan Li, Yalan
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Acta Biochimica et Biophysica Sinica
Bone cancer pain (BCP) is a common chronic pain that is caused by a primary or metastatic bone tumor. More detailed molecular mechanisms of BCP are warranted. In this study, we established a BCP rat model. The von Frey hair test, body weight, and hematoxylin and eosin staining were employed. We screened differentially expressed circRNAs (DECs) betw...
