Luo, Jinwen Zhu, Xiao Jian, Jie Chen, X u Yin, Kai
Published in
Acta Biochimica et Biophysica Sinica
The coronavirus disease-2019 (COVID-19) caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly developed into a global pneumonia pandemic. At present, COVID-19 has caused more than 70,000,000 confirmed cases with over 1,500,000 deaths worldwide, as reported by WHO. Cardiovascular disease is the majo...
Qi, Huan Ma, Mingliang Lai, Danyun Li, Yang Zhang, Fucheng Tao, Sheng-ce
Published in
Acta Biochimica et Biophysica Sinica
Zhao, Zhijuan Cui, Xiaodong Ma, Xiaoli Wang, Zhuanhua
Published in
Acta Biochimica et Biophysica Sinica
The self-nanoemulsifying drug delivery system has shown many advantages in drug delivery. In this study, a self-nanoemulsifying drug delivery system of buckwheat flavonoids was prepared for enhancing its antioxidant activity and oral bioavailability. A nanoemulsion of buckwheat flavonoids was developed and characterized, and its antioxidant, in vit...
Bosevski, Marijan Krstevski, Gorjan Bosevska, Golubinka Kapsarov, Kosta Dodic, Emilija Feehan, Jack Stojanoska, Lily Apostolopoulos, Vasso
Published in
Acta Biochimica et Biophysica Sinica
Shi, Rongfeng Lian, Weishuai Jin, Yinpeng Cao, Chuanwu Han, Shilong Yang, Xiaohu Zhao, Suming Li, Maoquan Zhao, Hui
Published in
Acta Biochimica et Biophysica Sinica
Diabetic foot ulcer (DFU) is one of diabetic complications, which is frequently present and tormented in diabetes mellitus. Most multipotent mesenchymal stromal cells (MSCs) are capable of immune evasion, providing an allogeneic, ready-to-use, cell product option for therapeutic applications. The beneficial effect of MSCs for the treatment of a var...
Xu, Guangmeng Sun, Yajuan He, Huaiqiang Xue, Qiuli Liu, Yajie Dong, Lihua
Published in
Acta Biochimica et Biophysica Sinica
In this study, we aimed to explore the effect of TrkB-PLC/IP3 pathway on intestinal inflammatory factors and enterocyte apoptosis in mice with colitis. The mouse model of ulcerative colitis was established by medication, and 40 SPF C57BL/6J mice (8 weeks old) were randomly divided into normal group (healthy mice, n = 10), control group (sham-operat...
Zhang, Yiwen Zhang, Xiaoxia Xing, Zumin Tang, Shuyi Chen, Hanwen Zhang, Zhongqi Li, Jiyuan Li, Yalan
Published in
Acta Biochimica et Biophysica Sinica
Bone cancer pain (BCP) is a common chronic pain that is caused by a primary or metastatic bone tumor. More detailed molecular mechanisms of BCP are warranted. In this study, we established a BCP rat model. The von Frey hair test, body weight, and hematoxylin and eosin staining were employed. We screened differentially expressed circRNAs (DECs) betw...
Yang, Xin Arslan, Mehboob Liu, Xingjian Song, Haozhi Du, Mengtan Li, Yinü Zhang, Zhifang
Published in
Acta Biochimica et Biophysica Sinica
Newcastle disease virus (NDV) causes severe economic losses through severe morbidity and mortality and poses a significant threat to the global poultry industry. Significant efforts have been made to develop novel vaccines and therapeutics; however, the interaction of NDV with the host is not yet fully understood. Interferons (IFNs), an integral co...
Saremi, Kamelia Rad, Sima Kianpour Khalilzadeh, Maryam Hussaini, Jamal Majid, Nazia Abdul
Published in
Acta Biochimica et Biophysica Sinica
Chlorine is shown to possess anti-gastric ulcer activity, since it can inactivate Helicobacter pylori , which is regarded as one of the most common risk factors for causing gastric problems. In the current study, the gastroprotective property of a novel dichloro-substituted Schiff base complex, 2, 2′- [−1, 2-cyclohexanediylbis(nitriloethylidyne)] b...
Hao, Pan Cui, Xia Liu, Jing Li, Muzi Fu, Yong Liu, Qun
Published in
Acta biochimica et biophysica Sinica
Few information of the function of stearoyl-coenzyme A (CoA) desaturase (SCD) in apicomplaxan parasite has been obtained. In this study, we retrieved a putative fatty acyl-CoA desaturase (TGGT1_238950) by a protein alignment with Plasmodium falciparum SCD in ToxoDB. A typical Δ9-desaturase domain was revealed in this protein. The putative desaturas...
