Bhattarai, Chacchu Poudel, Phanindra Prasad Ghosh, Arnab Kalthur, Sneha Guruprasad
Published in
AIMS Neuroscience
Enteric neurons and ganglia are derived from vagal and sacral neural crest cells, which undergo migration from the neural tube to the gut wall. In the gut wall, they first undergo rostrocaudal migration followed by migration from the superficial to deep layers. After migration, they proliferate and differentiate into the enteric plexus. Expression ...
Das, Ritwik Luczak, Artur
Published in
AIMS Neuroscience
Epileptogenesis is a complex and not well understood phenomenon. Here, we explore the hypothesis that epileptogenesis could be “hijacking” normal memory processes, and how this hypothesis may provide new directions for epilepsy treatment. First, we review similarities between the hypersynchronous circuits observed in epilepsy and memory consolidati...
Lorenzo, Jhunlyn Binczak, Stéphane Jacquir, Sabir
Published in
AIMS Neuroscience
Advances in neuronal studies suggest that a single neuron can perform integration functions previously associated only with neuronal networks. Here, we proposed a dendritic abstraction employing a dynamic thresholding function that models the spatiotemporal dendritic integration process of a CA3 pyramidal neuron. First, we developed an input-output...
Chaoui, Nouhaila Anarghou, Hammou Laaroussi, Meriem Essaidi, Oumaima Najimi, Mohamed Chigr, Fatiha
Published in
AIMS Neuroscience
Exposure to certain acute stressors results in an immediate behavioral and physiological response to these situations during a significant period of days. The goal of the current study is to evaluate the long-lasting effect of single exposure of restraint stress among mice after 0 h, 24 h, 48 h and 72 h. Five groups of mice are under experiment: a ...
Al-Amin, Md Mamun Sullivan, Robert K P Alexander, Suzy Carter, David A Bradford, DanaKai Burne, Thomas H J
Published in
AIMS neuroscience
Vitamin D deficiency is prevalent in adults and is associated with cognitive impairment. However, the mechanism by which adult vitamin D (AVD) deficiency affects cognitive function remains unclear. We examined spatial memory impairment in AVD-deficient BALB/c mice and its underlying mechanism by measuring spine density, long term potentiation (LTP)...
Park, Chan Hong Lee, Sang Ho
Published in
AIMS Neuroscience
Background Low back pain (LBP) is caused by disc herniation, spinal stenosis, facet syndrome or etc. This LBP could be either nociceptive or neuropathic pain (NP). In addition, these neuropathic pain is a major contributor to chronic low back pain. It is already known that lumbar epidural steroid injection (ESI) is effective for low back pain, but ...
Tevzadze, Gigi Barbakadze, Tamar Kvergelidze, Elisabed Zhuravliova, Elene Shanshiashvili, Lali Mikeladze, David
Published in
AIMS Neuroscience
Increased p-cresol levels reportedly alter brain dopamine metabolism and exacerbate neurological disorders in experimental animals. In contrast to toxic concentrations, low doses of p-cresol may have distinct effects on neuronal metabolism. However, the role of p-cresol in synapse remodeling, neurite outgrowth, and other anabolic processes in neuro...
Obayashi, Shigeru
Published in
AIMS Neuroscience
Thalamic stroke may result in cognitive and linguistic problems, but the underlying mechanism remains unknown. Especially, it is still a matter of debate why thalamic aphasia occasionally occurs and then mostly recovers to some degree. We begin with a brief overview of the cognitive dysfunction and aphasia, and then review previous hypotheses of th...
Abd-El-Basset, Ebtesam M Rao, Muddanna Sakkattu Alshawaf, Solaiman M Ashkanani, Hasan Kh Kabli, Abdulaziz H
Published in
AIMS Neuroscience
Objectives Neuro-inflammation occurs as a sequence of brain injury and is associated with production of cytokines. Cytokines can modulate the function and survival of neurons, microglia and astrocytes. The objective of this study is to examine the effect of TNF on the neurons, microglia and astrocytes in normal brain and stab wound brain injury. Me...
Nguyen, Khue Vu PhD
Published in
AIMS Neuroscience
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorders of purine metabolic in which the cytoplasmic enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. Despite having been characterized over 60 years ago, however, up to now, there is no satisfactory explanation of how deficits in enzyme HGprt can lead...
