Floris-Moore, Michelle Edmonds, Andrew Napravnik, Sonia Adimora, Adaora A
Published in
AIDS research and human retroviruses
This pilot study assessed feasibility of computer-assisted electronic medical record (EMR) abstraction to ascertain coronary heart disease (CHD) event hospitalizations. We included a sample of 87 hospitalization records from participants the University of North Carolina (UNC) site of the Women's Interagency HIV Study (WIHS) and UNC Center for AIDS ...
Castillo-Mancilla, Jose R Coyle, Ryan P Coleman, Stacey S Morrow, Mary Gardner, Edward M Zheng, Jia-Hua Ellison, Lucas Bushman, Lane R Kiser, Jennifer J MaWhinney, Samantha
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Published in
AIDS research and human retroviruses
Variable adherence to antiretroviral therapy (ART) can maintain HIV viral suppression, but our understanding of the ART adherence continuum remains limited. In a clinical cohort of adult persons living with HIV treated with a tenofovir (TFV) disoproxil fumarate/emtricitabine (TDF/FTC)-based regimen, data on 3-month self-reported adherence and dried...
Erlandson, Kristine M Bradford, Yuki Samuels, David C Brown, Todd T Sun, Jing Wu, Kunling Tassiopoulos, Katherine Ritchie, Marylyn D Haas, David W Hulgan, Todd
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Published in
AIDS research and human retroviruses
Mitochondrial DNA (mtDNA) haplogroup has been associated with disease risk and longevity. Among persons with HIV (PWH), mtDNA haplogroup has been associated with AIDS progression, neuropathy, cognitive impairment, and gait speed decline. We sought to determine whether haplogroup is associated with frailty and its components among older PWH. A cross...
Boffito, Marta Waters, Laura Cahn, Pedro Paredes, Roger Koteff, Justin Van Wyk, Jean Vincent, Tia Demarest, James Adkison, Kimberly Quercia, Romina
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Published in
AIDS research and human retroviruses
In HIV-1-infected patients, virological failure can occur as a consequence of the mutations that accumulate in the viral genome that allow replication to continue in the presence of antiretrovirals (ARVs). The development of treatment-emergent resistance to an ARV can limit a patient's options for future therapy, prompting the need for ARV regimens...
Paim, Ana C Badley, Andrew D Cummins, Nathan W
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AIDS research and human retroviruses
Human immunodeficiency virus-1 (HIV-1) causes CD4 T cell depletion through a number of mechanisms, including programmed cell death pathways (both apoptotic and nonapoptotic). In the setting of HIV-1 infection, the enhanced lymphocyte cell death occurs as a consequence of complex interactions between the host immune system and viral factors, which a...
Schneider, Edward Sarkar, Sudipa Margolick, Joseph B Martin, Seth Post, Wendy Brown, Todd
Published in
AIDS research and human retroviruses
Compared to those without human immunodeficiency virus (HIV) -infection, those that are HIV-infected are 1.5 to 2 times more likely to develop atherosclerotic cardiovascular disease (ASCVD) and to do so at a younger age. This increased risk is due to traditional risk factors (e.g., hypertension, diabetes, smoking and dyslipidemia), but also to fact...
Sauermilch, Daniel
Published in
AIDS research and human retroviruses
Researchers studying the mental health implications of HIV continue to conflate institutional mistrust (i.e., medical and/or governmental) with HIV conspiracy theory belief in spite of a multitude of existing scales that measure both independently. While this conflation is made frequently, measuring for HIV conspiracy theory belief in select (large...
Sellier, Pierre Hamet, Gwenn Brun, Alexandre Ponscarme, Diane De Castro, Nathalie Alexandre, Guylaine Rozenbaum, Willy Molina, Jean-Michel Abgrall, Sophie
Published in
AIDS research and human retroviruses
In high-income countries, causes of death in people living with HIV (PLHIV) have changed. Three French national surveys from 2000 to 2010 showed a decrease in AIDS-related and an increase in non-AIDS-related deaths. Deaths notified in PLHIV followed between January 1, 2011 and December 31, 2015 in 1 of 13 participating hospitals northeast of Paris ...
Temereanca, Aura Ene, Luminita Rosca, Adelina Diaconu, Carmen C Luca, Anca Burlacu, Ruxandra Radoi, Roxana Bulacu-Talnariu, Adina Marcotte, Thomas D Achim, Cristian L
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Published in
AIDS research and human retroviruses
HIV-associated neurocognitive disorders (HAND) continue to be reported even in patients with successful antiretroviral treatment. We investigated the prevalence of neurocognitive impairment and possible HIV-associated determinants of cognition in a Romanian cohort of young adults, parenterally infected with HIV during their first years of life. Two...
Brickman, Cristina E Propert, Kathleen J Merlin, Jessica S Liu, Jeffrey C Eady, Sequoya Mcghee-Jez, Amy Ragin, Camille Grover, Surbhi Cohen, Roger B Gross, Robert
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Published in
AIDS research and human retroviruses
HIV-positive people are at increased risk for malignancies associated with human papillomavirus (HPV) infection, including oropharyngeal squamous cell carcinoma (OPSCC). The purpose of this study was to determine whether cancer treatment disparities exist between HIV-positive and HIV-negative people with OPSCC. We conducted a retrospective cohort s...
