Published in AIDS research and human retroviruses
Multiple HIV-1 genotypes were found circulating in Guangdong Province, China, as this province is located in South China and has a high frequency of international trade. In this study, we report the near full-length genome (NFLG) of CRF12_BF that was identified from a male patient in Guangzhou city, Guangdong Province; this is the first time CRF12_...
Published in AIDS research and human retroviruses
We reported a novel human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) among four epidemiologically unlinked patients through men having sex with men in Heilongjiang Province, China. It was named CRF107_01B (this is temporary as we have not received the CRF number from HIV databases). A near full-length genome phylogenet...
Published in AIDS research and human retroviruses
To explore the molecular epidemiological status of human immunodeficiency virus type 1 (HIV-1) in Ganzhou, China, eight HIV-1-positive outpatients were recruited from July 5 to 21, 2018. Six HIV-1 near-full-length sequences were amplified and sequenced from the plasma samples that were collected before the patients' antiretroviral treatments. Phylo...
Published in AIDS research and human retroviruses
A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigational antiretroviral. Seven HIV-1-negative participan...
Published in AIDS research and human retroviruses
It is now recognized that to fully understand the role of host genetic variation on susceptibility to HIV-1 infection, investigations must be extended to African populations. We sought to determine if genetic variation in IL10 are associated with HIV-1 infection in a West African cohort in Mali. HIV-infected and -uninfected individuals were genotyp...
Published in AIDS research and human retroviruses
An important component underlying the disparity in HIV risk between race/ ethnic groups is the preferential transmission between individuals in the same group. We sought to quantify transmission between different race/ethnicity groups and measure racial assortativity in HIV transmission networks in major metropolitan areas in the United States. We ...
Published in AIDS research and human retroviruses
Human Immunodeficiency Virus-1 (HIV-1) causes millions of deaths around the world. Higher disease progression and mortality is seen in HIV positive individuals with co-morbidities. Two of the most pertinent conditions are co-infection with Mycobacterium tuberculosis (Mtb) and Intravenous Drug abuse. The mechanisms involved however, still remain unr...
Published in AIDS research and human retroviruses
To explore the molecular epidemiological status of human immunodeficiency virus type 1 (HIV-1) in Yunnan, China, three HIV-1 near-full-length genomes were amplified and sequenced from plasma samples that were collected from Burmese patients newly diagnosed with HIV-1 in Dehong Prefecture in Yunnan Province in 2017. Phylogenetic and bootscanning ana...
Published in AIDS research and human retroviruses
The HIV-1 CRF07_BC strain has been increasing in frequency in China, is now the major recombination subtype in the men who have sex with men (MSM) population. However, to date, the evolutionary history of CRF07_BC in MSM in China has not been explored in greater detail. All available partial gag, pol and env segments of CRF07_BC were obtained from ...
Published in AIDS research and human retroviruses
Isolation and culture of HIV is an important basis for AIDS etiology, immunolo-gy, drug screening, clinical treatment, and vaccine research. CRF01_AE is one of the predominant strains of HIV-1 in China. However, there are few HIV-1 CRF01_AE isolates that have been reported. In this study, sixteen HIV-1 CRF01_AE strains from Guangxi, China were isol...
