Zhu, Dan Xu, Jilin Chen, Hui Wang, Saibin Yu, Long
Published in
AIDS research and human retroviruses
Advanced age is a high-risk factor for exacerbation of coronavirus disease 2019 (COVID-19), which causes a high rate of mortality. Therefore, it is important to strengthen the warning and monitoring of severe patients, and early identify the severe and critically severe types in time in the clinical treatment of COVID-19. Moreover, it is necessary ...
Farinacci, Damiano Ciccullo, Arturo Borghetti, Alberto Visconti, Elena Tamburrini, Enrica Izzi, Immacolata Maria Cauda, Roberto Di Giambenedetto, Simona Pallavicini, Federico
Published in
AIDS research and human retroviruses
Al-Harthi, Lena Campbell, Edward Schneider, Julie A Bennett, David A
Published in
AIDS research and human retroviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of COVID-19, a disease that as of July 10, 2020, has infected >12 million people and killed >500,000. COVID-19 infection leads to acute respiratory distress syndrome in a subset of patients and is a primary driver of acute morbidity in infected persons. However, it ...
Staitieh, Bashar S Auld, Sara C Ahmed, Mariam Fan, Xian Smirnova, Natalia Yeligar, Samantha M
Published in
AIDS research and human retroviruses
Despite the advent of antiretroviral therapy, people living with HIV suffer from a range of infectious and noninfectious pulmonary complications. HIV impairs antioxidant defenses and innate immune function of the alveolar macrophage by diminishing granulocyte macrophage-colony stimulating factor (GM-CSF) signaling. Since GM-CSF may be linked to mit...
Lan, Yun He, Xiang Xin, Ruolei Li, Linghua Huang, Xuhe Deng, Xizi Tang, Xiaoping Jia, Weidong Cai, Weiping Hu, Fengyu
...
Published in
AIDS research and human retroviruses
Multiple HIV-1 genotypes were found circulating in Guangdong Province, China, as this province is located in South China and has a high frequency of international trade. In this study, we report the near full-length genome (NFLG) of CRF12_BF that was identified from a male patient in Guangzhou city, Guangdong Province; this is the first time CRF12_...
Song, Xiao Zhou, Jiajia Li, Miaomiao Feng, Yi Xing, Hui Wei, Sun
Published in
AIDS research and human retroviruses
We reported a novel human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) among four epidemiologically unlinked patients through men having sex with men in Heilongjiang Province, China. It was named CRF107_01B (this is temporary as we have not received the CRF number from HIV databases). A near full-length genome phylogenet...
Xie, Ying-Na Zhang, Yu-Ning Cheng, Si-Wei Huang, Dan-Dan Xie, Bing-Yu Huang, Zhen Zhou, Yan-Heng Zhu, Da-Qing Chen, Xin
Published in
AIDS research and human retroviruses
To explore the molecular epidemiological status of human immunodeficiency virus type 1 (HIV-1) in Ganzhou, China, eight HIV-1-positive outpatients were recruited from July 5 to 21, 2018. Six HIV-1 near-full-length sequences were amplified and sequenced from the plasma samples that were collected before the patients' antiretroviral treatments. Phylo...
Al-Khouja, Amer Shieh, Eugenie Fuchs, Edward J Marzinke, Mark A Bakshi, Rahul P Hummert, Pamela Ham, Anthony S Buckheit, Karen W Breakey, Jennifer Weld, Ethel D
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Published in
AIDS research and human retroviruses
A lubricating microbicide gel designed for rectal and vaginal use would provide a behaviorally congruent strategy to enhance pre-exposure prophylaxis adherence and reduce HIV infection risk. In this study, we report the first-in-human evaluation of such a gel containing 1% IQP-0528, an investigational antiretroviral. Seven HIV-1-negative participan...
Dabitao, Djeneba Dembele, Mamadou Urbanowski, Michael Kone, Bourahima Wague, Mamadou Coulibaly, Nadie Sarro, Yeya Dit Sadio Baya, Bocar Goita, Drissa Dao, Sounkalo
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Published in
AIDS research and human retroviruses
It is now recognized that to fully understand the role of host genetic variation on susceptibility to HIV-1 infection, investigations must be extended to African populations. We sought to determine if genetic variation in IL10 are associated with HIV-1 infection in a West African cohort in Mali. HIV-infected and -uninfected individuals were genotyp...
Ragonnet-Cronin, Manon Benbow, Nanette Hayford, Christina Poortinga, Kathleen Ma, Fangchao Forgione, Lisa A Sheng, Zhijuan Hu, Yunyin Torian, Lucia Wertheim, Joel O
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Published in
AIDS research and human retroviruses
An important component underlying the disparity in HIV risk between race/ ethnic groups is the preferential transmission between individuals in the same group. We sought to quantify transmission between different race/ethnicity groups and measure racial assortativity in HIV transmission networks in major metropolitan areas in the United States. We ...
