Boffito, Marta Waters, Laura Cahn, Pedro Paredes, Roger Koteff, Justin Van Wyk, Jean Vincent, Tia Demarest, James Adkison, Kimberly Quercia, Romina
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Published in
AIDS research and human retroviruses
In HIV-1-infected patients, virological failure can occur as a consequence of the mutations that accumulate in the viral genome that allow replication to continue in the presence of antiretrovirals (ARVs). The development of treatment-emergent resistance to an ARV can limit a patient's options for future therapy, prompting the need for ARV regimens...
Wu, Guohui Zhou, Chao Zhang, Xiangjun Zhang, Wei Lu, Rongrong Ouyang, Lin Xing, Hui Shao, Yiming Ruan, Yuhua Qian, Han-Zhu
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Published in
AIDS Research and Human Retroviruses
Older people living with HIV (PLWH) may have delayed diagnosis and access to care and therefore have poorer disease outcomes. Little is known about HIV care and disease outcomes among older PLWH in China. This retrospective cohort study used data from all adult HIV/AIDS cases during 1988–2017 in Chongqing, China from two national databases. We comp...
Kafando, Alexis Serhir, Bouchra Doualla-Bell, Florence Fournier, Eric Sangaré, Mohamed Ndongo Martineau, Christine Sylla, Mohamed Chamberland, Annie El-Far, Mohamed Charest, Hugues
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Published in
AIDS research and human retroviruses
The identification of transmission clusters (TCs) of HIV-1 using phylogenetic analyses can provide insights into viral transmission network and help improve prevention strategies. We compared the use of partial HIV-1 envelope fragment of 1,070 bp with its loop 3 (108 bp) to determine its utility in inferring HIV-1 transmission clustering. Serum sam...
McManus, Kathleen A Debolt, Claire Elwood, Sarah Saint-Surin, Tamara Winstead-Derlega, Christopher Brennan, Robert O Dillingham, Rebecca Flickinger, Tabor E
Published in
AIDS research and human retroviruses
Many AIDS drug assistance programs (ADAPs) purchased Affordable Care Act (ACA) qualified health plans (QHPs) for low-income people living with HIV. To date, little has been written about this from the client perspective. The study's objective was to gain information about the experience of Virginia ADAP-funded QHP enrollment and the impact of this ...
Shacklett, Barbara L Blanco, Julià Hightow-Weidman, Lisa Mgodi, Nyaradzo Alcamí, José Buchbinder, Susan Chirenje, Mike Dabee, Smritee Diallo, Mamadou Dumchev, Kostyantyn
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Published in
AIDS research and human retroviruses
The HIV Research for Prevention (HIVR4P) conference is dedicated to advancing HIV prevention research, responding to a growing consensus that effective and durable prevention will require a combination of approaches as well as unprecedented collaboration among scientists, practitioners, and community workers from different fields and geographic are...
Lamers, Susanna L Fogel, Gary B Nolan, David J Barbier, Andrew E Rose, Rebecca Singer, Elyse J Gonzalez-Perez, Maria Paz McGrath, Michael S
Published in
AIDS research and human retroviruses
The HIV envelope protein contains five hypervariable domains (V1-V5) that are fundamental for cell entry. We contrasted modifications in the variable domains derived from a panel of 24 tissues from 7 subjects with no measurable plasma viral load (NPVL) to variable domains from 76 tissues from 15 subjects who had a detectable plasma viral load (PVL)...
Bull, Marta E. McKernan, Jennifer L. Styrchak, Sheila Kraft, Kelli Hitti, Jane Cohn, Susan E. Tapia, Kenneth Deng, Wenjie Holte, Sarah Mullins, James I.
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Published in
AIDS Research and Human Retroviruses
Identifying tissue sources of HIV that rebound following “failure” of antiretroviral therapy (ART) is critical to evaluating cure strategies. To assess the role of the uterine cervix and peripheral blood mononuclear cells (PBMC) as viral reservoirs, nearest-neighbor phylogenetic analyses compared genetic relatedness of tissue sequences during ART s...
Furler, Robert L Nixon, Douglas F
Published in
AIDS research and human retroviruses
Summers, Nathan A Kelley, Colleen F Armstrong, Wendy Marconi, Vincent C Nguyen, Minh Ly
Published in
AIDS research and human retroviruses
Progressive multifocal leukoencephalopathy (PML) and PML immune reconstitution inflammatory syndrome (PML-IRIS) can be devastating neurological processes associated with HIV, but limited knowledge of their characteristics in the established antiretroviral therapy (ART) era is available. We conducted a case series to evaluate the clinical course of ...
Weiner, Lukasz D Retuerto, Mauricio Hager, Christopher L El Kamari, Vanessa Shan, Lingpeng Sattar, Abdus Kulkarni, Manjusha Funderburg, Nicholas Ghannoum, Mahmoud A Dirajlal-Fargo, Sahera
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Published in
AIDS research and human retroviruses
The mechanisms causing HIV-associated immune activation remain incompletely understood. Alteration of intestinal integrity with subsequent translocation of bacterial products appears to play an important role; however, little is known about the impact of fungal translocation. We assessed the effect of fungal translocation and its association with i...
