Sherman, Brad T. Hu, Xiaojun Singh, Kanal Haine, Lillian Rupert, Adam W. Neaton, James D. Lundgren, Jens D. Imamichi, Tomozumi Chang, Weizhong Lane, H. Clifford
...
Published in
AIDS (London, England)
Elevated levels of interleukin-6 (IL-6), D-dimer, and C-reactive protein (hsCRP) are associated with increased incidence of comorbid disease and mortality among people living with HIV (PLWH). Prior studies suggest a genetic basis for these biomarker elevations in the general population. The study objectives are to identify the genetic basis for the...
Rein, Sophia M Lampe, Fiona C Johnson, Margaret A Bhagani, Sanjay Miller, Robert F Chaloner, Clinton Phillips, Andrew N Burns, Fiona M Smith, Colette J
Published in
AIDS (London, England)
We investigated differences in all-cause hospitalisation between key demographic groups among people with HIV in the UK in the current ART era. We used data from the Royal Free HIV Cohort study between 2007 and 2018. Individuals were classified into five groups: men who have sex with men (MSM), Black African men who have sex with women (MSW), MSW o...
Shanaube, Kwame Schaap, Ab Hoddinott, Graeme Mubekapi-Musadaidzwa, Constance Floyd, Sian Bock, Peter Hayes, Richard Fidler, Sarah Ayles, Helen
Published in
AIDS (London, England)
To determine the impact of a community-wide combination HIV-prevention package (PopART Intervention) that includes universal testing and treatment (UTT) on knowledge of HIV-status, among adolescents aged 15-19 years. The HPTN 071 (PopART) for Youth (P-ART-Y) study was nested within HPTN 071 (PopART), a 3-arm, cluster-randomized trial conducted from...
Nichols, Brooke E Cele, Refiloe Jamieson, Lise Long, Lawrence C Siwale, Zumbe Banda, Patrick Moyo, Crispin Rosen, Sydney
Published in
AIDS (London, England)
To determine the total annual cost per patient treated and total cost per patient retained on antiretroviral therapy in Zambia in conventional care in facilities and across community-based differentiated service delivery (DSD) models. Economic evaluation using retrospective electronic record review. Twenty healthcare facilities (13 with DSD models ...
Pasvol, Thomas J. Teh, Jhia Balfoussia, Danai Hall, Rebecca Petersen, Claire Khan, Maryam Ayres, Sara Jayasena, Channa N. Foster, Caroline Fidler, Sarah
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Published in
AIDS (London, England)
There are no published studies of fertility measurements in people living with perinatally acquired HIV (PaHIV). We performed fertility investigations in 25 adults with PaHIV. Seven (78%) men had sperm morphology normal forms (%) below the fifth centile for the general population with four (44%) having no normal forms. Mean (SD) serum anti-Mülleria...
Chandiwana, Nomathemba C. Chersich, Matthew Venter, W.D. François Akpomiemie, Godspower Hill, Andrew Simmons, Bryony Lockman, Shahin Serenata, Celicia M. Fairlie, Lee Moorhouse, Michelle A.
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Published in
AIDS (London, England)
Dolutegravir exposure at conception was associated with a preliminary signal of increased infant neural tube defect risk. As low maternal folate levels are linked with neural tube defects, we aimed to assess serum folate concentrations in women starting dolutegravir. Design: We analysed serum folate concentrations from stored plasma among women enr...
Hsu, Ricky Brunet, Laurence Fusco, Jennifer S Mounzer, Karam Vannappagari, Vani Henegar, Cassidy E Van Wyk, Jean Curtis, Lloyd Lo, Janet Fusco, Gregory P
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Published in
AIDS (London, England)
To describe the prevalence and incidence of prediabetes and type 2 diabetes mellitus (T2DM) among people living with HIV (PLHIV) and evaluate the association between antiretroviral therapy (ART) initiation with dolutegravir (DTG), elvitegravir/cobicistat (EVG/c), raltegravir (RAL), or boosted darunavir (bDRV) and incident T2DM. Longitudinal study b...
Whiteman, Ari Baugher, Amy Sionean, Catlainn
Published in
AIDS (London, England)
To determine the prevalence of four forms of sexual identity discrimination among MSM in 23 US metropolitan statistical areas, examine racial/ethnic and socioeconomic disparities in each form of discrimination. We examined interview data collected during 2017 for National HIV Behavioral Surveillance (n = 10 029 respondents) and used generalized lin...
Jones, Chloe I Rose, Suzanne L Shutt, Ashley Cairo, Cristiana Bourgeois, Natasha M Charurat, Manhattan Sodora, Donald L Wood, Matthew P
Published in
AIDS (London, England)
HIV-exposed uninfected (HEU) infants exhibit altered vaccine responses and an increased mortality compared with HIV-unexposed infants. Here, vaccine responses in HEU and HIV-unexposed cord blood monocytes (CBMs) were assessed following Bacillus Calmette--Guerín (BCG) treatment. Innate responses to in-vitro BCG treatment were assessed through transc...
Orkin, Chloe Elion, Richard Thompson, Melanie Rockstroh, Juergen K Alvarez Bognar, Fernando Xu, Zhi J Hwang, Carey Sklar, Peter Martin, Elizabeth A
Published in
AIDS (London, England)
To evaluate changes in weight and BMI in adults with HIV-1 at 1 and 2 years after starting an antiretroviral regimen that included doravirine, ritonavir-boosted darunavir, or efavirenz. Post-hoc analysis of pooled data from three randomized controlled trials. We evaluated weight change from baseline, weight gain at least 10%, and increase in BMI af...
