Yazdian, Aaron Minuk, Jeffrey Hemenway, Gregory Upadhyaya, Neelam Vaz, Cherie Lisa
Published in
AACE clinical case reports
Ectopic tumoral production of parathyroid hormone (PTH) is rare. The incidence of hyperparathyroidism and osteitis fibrosa cystica (OFC) secondary to ectopic PTH secretion has only been reported in case reports, although infrequent. We report a case of a well-differentiated pulmonary neuroendocrine tumor (NET) producing PTH that presented with seve...
Jasim, Sina
Published in
AACE clinical case reports
Rajamani, Krishnakumar Moore, Richard G Stanard, Sheena M Astapova, Olga
Published in
AACE clinical case reports
Epithelial cell ovarian carcinomas rarely secrete steroid hormones, while sex cord and stromal cell ovarian carcinomas often do so. The objective of this report is to describe a patient with endometrioid ovarian carcinoma, an epithelial cell tumor, who presented with hyperandrogenism due to testosterone production by the tumor. A 67-year-old postme...
Jasim, Sina
Published in
AACE clinical case reports
Karalis, John D Jia, Liwei Murvelashvili, Natia Vora, Amy Tessnow, Alex Dackiw, Alan P B
Published in
AACE clinical case reports
Distant metastases from papillary thyroid carcinoma (PTC) are relatively rare and may be associated with a poor prognosis. The adrenal gland is a highly unusual site of metastasis in the natural course of PTC. Herein, we describe a case of an incidentally detected metastatic solid variant of PTC in the adrenal gland of an asymptomatic patient as th...
Silvestri, Francesca Tromba, Valeria Costantino, Francesco Palaniappan, Nila Urano, Fumihiko
Published in
AACE clinical case reports
Early diagnosis of syndromic monogenic diabetes allows for proper management and can lead to improved quality of life in the long term. This report aimed to describe 2 genetically confirmed cases of Wolfram syndrome, a rare endoplasmic reticulum disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy, and progressive neur...
Zimmerman, Chelsea F Ilstad-Minnihan, Alexandra B Bruggeman, Brittany S Bruggeman, Bradley J Dayton, Kristin J Joseph, Nancy Moas, Daniel I Rohrs, Henry J
Published in
AACE clinical case reports
Transient thyrotoxicosis has been documented in the setting of hyperemesis gravidarum (HG) with elevated human chorionic gonadotropin (hCG) levels. Thyroid storm in pregnancy is rarer and typically associated with autoimmune hyperthyroidism. We described thyroid storm in a primigravid 18-year-old patient due to hCG level elevation secondary to HG, ...
Folick, Andrew Cheng, Cheng Chu, Simon N Rick, Jonathan W Rushakoff, Robert J
Published in
AACE clinical case reports
Oral hypoglycemic agents are a frequent cause of hypoglycemia in nondiabetic people. Here, we report a case of recurrent hypoglycemia caused by glipizide, in which diagnosis was delayed because of a combination of delayed hypoglycemic agent screening and low sensitivity of the hypoglycemic agent screening panel used. A 66-year-old woman repeatedly ...
Parksook, Wasita Warachit Porntharukchareon, Thachanun Sunthornyothin, Sarat
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AACE clinical case reports
Hypothalamic-pituitary-adrenal axis stimulation during pregnancy complicates the investigation of Cushing's syndrome (CS). Our objective was to present the case of a pregnant patient with CS caused by a pituitary tumor in whom the desmopressin stimulation test helped in the diagnosis and led to appropriate management. A 27-year-old woman with 9-wee...
Ochoa Molina, Maria Fernanda Poggi, Helena De Toro, Valeria Mendoza, Carolina Hussain, Khalid
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AACE clinical case reports
AKT2 is a serine/threonine kinase that plays a key role in regulating insulin signaling. The phenotype related to the gain-of-function alteration in the AKT2 gene (c.49G>A, p.Glu17Lys) has been described in 5 patients with clinical findings that mimic hyperinsulinemic hypoglycemia but with undetectable levels of insulin and C-peptide. One of the re...
